Results 31 to 40 of about 4,302 (241)

The pterin molybdenum cofactors.

Journal of Biological Chemistry, 1992
crassa, demonstrated that the inactive apoprotein of nitrate reductase in extracts of the mutant could be reconstituted by the addition of denatured preparations of purified molybdoenzymes from animal, fungal, or bacterial origin. This crucial finding showed that mol- ybdoenzymes contain a dissociable entity fitting the description of a cofactor and ...
K.V. Rajagopalan, Jean L. Johnson
openaire   +3 more sources

Exploring the scope of DBU-promoted amidations of 7-methoxycarbonylpterin

Beilstein Journal of Organic Chemistry, 2020
The synthetic utility of pterins is often hampered by the notorious insolubility of this heterocycle, slowing the development of medicinally relevant pteridine derivatives.
Anna R. Bockman, Jeffrey M. Pruet
doaj   +1 more source

Synthetic studies on pterin glycosides: the first synthesis of 2′-O-(α-d-glucopyranosyl)biopterin [PDF]

, 2009
L-Rhamnose was led, in a 14-step-sequence, to N2-(N,N-dimethylaminomethylene)-1′-O-(4-methoxybenzyl)-3-[2-(4-nitrophenyl)ethyl]biopterin (23), an appropriately protected precursor for 2′-O-glycosylation, while 4,6-di-O-acetyl-2,3-di-O-(4-methoxybenzyl)-α-
Cha, Cho, Choi, Coolidge, Crane, Fitzpatrick, Forrest, Gigg, Hanaya, Hanaya, Hanaya, Hanaya, Hanaya, Hanessian, Hatfield, Hiroki Baba, Hiroki Toyota, Hiroshi Yamamoto, Hough, Ibatullin, Ikawa, Kaufman, Kaufman, Kwon, Lee, Lemieux, Lin, Lönn, Marletta, Matsunaga, Ness, Noguchi, Saito, Stewart, Suzuki, Tadashi Hanaya, Taylor, Wolfrom, Wulff, Yin   +39 more
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Soybean phosphatidylcholine liposomes as model membranes to study lipid peroxidation photoinduced by pterin [PDF]

, 2019
Oxidized pterins, efficient photosensitizers under UVA irradiation, accumulate in the skin of patients suffering from vitiligo, a chronic depigmentation disorder.
Catalá, Ángel, Thomas, Andrés Héctor, Vignoni, Mariana   +2 more
core   +3 more sources

Inactivation of tyrosinase photoinduced by pterin

Biochemical and Biophysical Research Communications, 2012
Tyrosinase catalyzes in mammals the first and rate-limiting step in the biosynthesis of the melanin, the main pigment of the skin. Pterins, heterocyclic compounds able to photoinduce oxidation of DNA and its components, accumulate in the skin of patients suffering from vitiligo, a chronic depigmentation disorder in which the protection against UV ...
Dantola, Maria Laura, Gojanovich, Aldana Daniela, Thomas, Andrés Héctor   +2 more
openaire   +4 more sources

Determination of Urinary Pterins by Capillary Electrophoresis Coupled with LED-Induced Fluorescence Detector

Molecules, 2019
Urinary pterins have been found as potential biomarkers in many pathophysiological conditions including inflammation, viral infections, and cancer. However, pterins determination in biological samples is difficult due to their degradation under exposure ...
Wojciech Grochocki, Magdalena Buszewska-Forajta, Szymon Macioszek, Michał J. Markuszewski   +3 more
doaj   +1 more source

Orientation of Pterin-6-Carboxylic Acid on Gold Capped Silicon Nanopillars Platforms: Surface Enhanced Raman Spectroscopy and Density Functional Theory Studies [PDF]

, 2015
The orientation of pterin-6-carboxylic acid on gold nanopillars was investigated by surface enhanced Raman spectroscopy and density functional theory methods.
Bertel, Linda, Boisen, Anja, Castillo, John J., Martinez Ortega, Fernando, Mendez-Sanchez, Stelia C., Rindzevicius, Tomas, Rozo, Ciro E.   +6 more
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Cerebrospinal Fluid Pterins, Pterin-Dependent Neurotransmitters, and Mortality in Pediatric Cerebral Malaria

The Journal of Infectious Diseases, 2021
Abstract Background Cerebral malaria (CM) pathogenesis remains incompletely understood. Having shown low systemic levels of tetrahydrobiopterin (BH4), an enzymatic cofactor for neurotransmitter synthesis, we hypothesized that BH4 and BH4-dependent neurotransmitters would likewise be low in ...
Salvatore M. Florence, Bert K. Lopansri, Bert K. Lopansri, Keith Hyland, Donald L. Granger, Sara Nakielny, Ryan A. Simmons, Tsin W. Yeo, Nicholas M. Anstey, Matthew P. Rubach, Esther D. Mwaikambo, Joseph L. DeRisi, Jackson Mukemba, J. Brice Weinberg, Charles Langelier   +14 more
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Structure of the first representative of Pfam family PF04016 (DUF364) reveals enolase and Rossmann-like folds that combine to form a unique active site with a possible role in heavy-metal chelation. [PDF]

, 2010
The crystal structure of Dhaf4260 from Desulfitobacterium hafniense DCB-2 was determined by single-wavelength anomalous diffraction (SAD) to a resolution of 2.01 Å using the semi-automated high-throughput pipeline of the Joint Center for Structural ...
Abdubek, Polat, Aravind, L, Astakhova, Tamara, Axelrod, Herbert L, Bakolitsa, Constantina, Carlton, Dennis, Chiu, Hsiu Ju, Clayton, Thomas, Deacon, Ashley M, Deller, Marc C, Duan, Lian, Elsliger, Marc André, Feuerhelm, Julie, Godzik, Adam, Grant, Joanna C, Han, Gye Won, Hodgson, Keith O, Jaroszewski, Lukasz, Jin, Kevin K, Klock, Heath E, Knuth, Mark W, Kozbial, Piotr, Krishna, S Sri, Kumar, Abhinav, Lesley, Scott A, Marciano, David, McMullan, Daniel, Miller, Mitchell D, Morse, Andrew T, Nigoghossian, Edward, Okach, Linda, Reyes, Ron, Rife, Christopher L, van den Bedem, Henry, Weekes, Dana, Wilson, Ian A, Wooley, John, Xu, Qingping   +37 more
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Tryptophan oxidation photosensitized by pterin

Free Radical Biology and Medicine, 2013
Pterins are normal components of cells and they have been previously identified as good photosensitizers under UV-A irradiation, inducing DNA damage and oxidation of nucleotides. In this work, we have investigated the ability of pterin (Ptr), the parent compound of oxidized pterins, to photosensitize the oxidation of another class of biomolecules ...
Thomas, Andrés, Serrano, Mariana, Rahal, Virginie, Vicendo, Patricia, Claparols, Catherine, Oliveros, Esther, Lorente, Carolina   +6 more
openaire   +6 more sources