Results 51 to 60 of about 1,595 (174)

The pterin molybdenum cofactors.

Journal of Biological Chemistry, 1992
crassa, demonstrated that the inactive apoprotein of nitrate reductase in extracts of the mutant could be reconstituted by the addition of denatured preparations of purified molybdoenzymes from animal, fungal, or bacterial origin. This crucial finding showed that mol- ybdoenzymes contain a dissociable entity fitting the description of a cofactor and ...
K V, Rajagopalan, J L, Johnson
openaire   +2 more sources

In Vivo Biosynthesis and Direct Incorporation of Noncanonical Amino Acids into Proteins

ChemBioChem, Volume 26, Issue 22, November 17, 2025.
This review evaluates engineered (semi)autonomous cell systems for the biosynthesis and incorporation of noncanonical amino acids (ncAAs) into proteins. While semi‐autonomous cells convert supplied precursors into ncAAs autonomous cells integrate biosynthetic pathways that produce these building blocks intracellularly.
Jan Hendrik Illies, Tim Moritz Weber, Ivana Drienovská   +2 more
wiley   +1 more source

A concise treatment of pterins: some recent synthetic and methodology aspects and their applications in molecular sensors

Pteridines, 2018
A concise account of pterins in chemistry and biology and their applications in molecular sensors including their optical spectroscopic properties are described.
Goswami Shyamaprosad, Das Manas Kumar, Sain Dibyendu, Goswami Bhaswati   +3 more
doaj   +1 more source

Identification of Novel Potential Inhibitors of Pteridine Reductase 1 in Trypanosoma brucei via Computational Structure-Based Approaches and in Vitro Inhibition Assays

Molecules, 2019
Pteridine reductase 1 (PTR1) is a trypanosomatid multifunctional enzyme that provides a mechanism for escape of dihydrofolate reductase (DHFR) inhibition. This is because PTR1 can reduce pterins and folates.
Magambo Phillip Kimuda, Dustin Laming, Heinrich C. Hoppe, Özlem Tastan Bishop   +3 more
doaj   +1 more source

Applications of QSPR and Machine Learning in Molecular Photonics

Advanced Optical Materials, Volume 13, Issue 33, November 25, 2025.
Quantitative structureproperty relationships (QSPR) and machine learning (ML) are transforming photochemistry by enabling pre‐synthetic screening of photoactive molecules. This review outlines advances in data‐driven discovery of optical materials and functional dyes, identifies effective descriptors and models for photophysical processes, and provides
Andrey A. Buglak, Platon P. Chebotaev, Mikhail A. Filatov   +2 more
wiley   +1 more source

An Allele of Glutamate Formiminotransferase Triggers 5‐Methyl‐Tetrahydrofolate‐to‐MeFox Conversion and Facilitates Folate Biofortification in Maize

Advanced Science, Volume 12, Issue 42, November 13, 2025.
This work demonstrates the distinct roles of the glutamate formiminotransferase (GFT) enzyme in plants. The GFT triggers the conversion of 5‐methyl‐tetrahydrofolate to MeFox in plants, a process distinct from its role as a formiminotransferase in mammals.
Tong Lian, Wenzhu Guo, Yanjing Wang, Weiwei Wen, Weixuan Wang, Ling Jiang, Qiuju Liang, Ji'an Liu, Haijun Liu, Yuan Xue, Lixu Pan, Qiaoquan Liu, Ping Yin, Delin Zhang, Jianbing Yan, Chunyi Zhang   +15 more
wiley   +1 more source

Metabolic Origin, Role and Fate of the Denaturant Guanidine

Microbial Biotechnology, Volume 18, Issue 11, November 2025.
The origin of metabolic guanidine is largely a mystery. We suggest it is created when guanine‐containing nucleotides are oxidised by molecular oxygen instead of being broken down into urea as purines normally would. Guanidine may act as a signal to help cells control the level of reactive oxygen species.
Antoine Danchin, Victor de Lorenzo, Pablo Iván Nikel, Conghui You   +3 more
wiley   +1 more source

Replicated Differential Expression Analysis in a Green‐Brown Polymorphic Grasshopper Reveals Role of Beta‐Carotene‐Binding Protein in Body Coloration

Molecular Ecology, Volume 34, Issue 22, November 2025.
ABSTRACT Orthoptera provide a well‐documented case of transspecies colour polymorphism, with green and brown morphs coexisting in many species. This colour polymorphism is likely under long‐term balancing selection, but the genetic and molecular mechanisms underlying the variation remain poorly understood.
Chongyi Jiang, Mahendra Varma, Abhijeet Shah, Octavio M. Palacios‐Gimenez, Holger Schielzeth   +4 more
wiley   +1 more source

Occurrence of Pterin Pigments in Hymenoptera [PDF]

Nature, 1950
IT has been found that pterins exist in tissues of animals belonging to nearly all groups; their occurrence as pigments, however, is restricted to insects and cold-blooded vertebrates1,2. Among Lepidoptera, they are always present in the wing-scales of the Pieridae and appear to be a biochemical characteristic of that natural family3,4.
openaire   +2 more sources

Neopterin as a Tool for Primate Ecoimmunology: Current Knowledge, Practical Application, and New Directions From Captivity to the Wild

American Journal of Primatology, Volume 87, Issue 10, October 2025.
Neopterin is a sensitive and specific biomarker of intracellular pathogen infection and chronic inflammation, and affected by environmental, life‐history, and sex‐contextual factors. This review offers best‐practice guidelines and practical advice on sample collection, storage, and analysis in primates when used for ecoimmunological conservation and ...
Verena Behringer, Caroline Deimel
wiley   +1 more source