Results 21 to 30 of about 8,591 (223)
Molecules, 2022 Puerarin (daidzein-8-C-glucoside) is an isoflavone isolated from several leguminous plants of the genus Pueraria. Puerarin possesses several pharmacological properties; however, the poor solubility of puerarin limits its applications.
Hsiou-Yu Ding +4 more
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Human Gut Microbial Degradation of Flavonoids: Structure−Function Relationships [PDF]
, 2005 The relationship between chemical structure and gut microbial degradation rates of 14 flavonoids, flavone, apigenin, chrysin, naringenin, kaempferol, genistein, daidzein, daidzin, puerarin, 7,4‘-dihydroxyflavone, 6,4‘-dihydroxyflavone, 5,4 ...
Hendrich, Suzanne +4 more
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BMC Complementary and Alternative Medicine, 2019 Background Puerarin exerts therapeutic effect on osteoporosis due to its inhibitory effect on the formation of osteoclasts. Puerarin is also widely established as an autophagy inhibitor.
Guoyou Zhang +3 more
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Effects of puerarin on the pharmacokinetics of astragaloside IV in rats and its potential mechanism
Pharmaceutical Biology, 2020 Context Puerarin and astragaloside IV (AS-IV) are sometimes used together for the treatment of disease in Chinese clinics, however, the drug–drug interaction between puerarin and AS-IV is still unknown.
Huan Zhang +4 more
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Plants-derived neuroprotective agents: Cutting the cycle of cell death through multiple mechanisms [PDF]
, 2017 Neuroprotection is the preservation of the structure and function of neurons from insults arising from cellular injuries induced by a variety of agents or neurodegenerative diseases (NDs).
Berida, Tomayo Ireti +2 more
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Puerarin Suppress Apoptosis of Human Osteoblasts via ERK Signaling Pathway
International Journal of Endocrinology, 2013 Puerarin, the main isoflavone glycoside extracted from Radix Puerariae, is an isoflavone traditional Chinese herb. Previous studies have demonstrated that puerarin could regulate osteoblast proliferation and differentiation to promote bone formation ...
Ling-juan Liu +6 more
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Medicago spp. as potential sources of bioactive isoflavones: Characterization according to phylogenetic and phenologic factors [PDF]
, 2015 A high variety of plant species are often proposed as potential natural sources of specific bioactive components, with emphasis in phenolic compounds. However, the ability to produce a determined phytochemical might be variable, even among species with ...
Barreira, João C.M. +5 more
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Contrast Media & Molecular Imaging, 2022 In order to evaluate the effects of puerarin combined with poly lactic‐co‐glycolic acid (PLGA)/tricalcium phosphate (TCP)/puerarin on osteocalcin and sialoprotein of mandibular defects, the obtained rat jaw cells are analyzed. The surface morphology of osteoblast complex in the scaffold material group and puerarin combined scaffold material group is ...
Ying Guo +5 more
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Effects of Puerariae Radix Extract on Endotoxin Receptors and TNF-α Expression Induced by Gut-Derived Endotoxin in Chronic Alcoholic Liver Injury [PDF]
, 2012 Kudzu (Pueraria lobata) is one of the earliest medicinal plants used to treat alcohol abuse in traditional Chinese medicine for more than a millennium. However, little is known about its effects on chronic alcoholic liver injury.
Fu Huang +7 more
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Immobilization of puerarin glycosidase from Microbacterium oxydans CGMCC 1788 increases puerarin transformation efficiency [PDF]
Brazilian Journal of Chemical Engineering, 2014 For immobilization of puerarin glycosidase from Microbacterium oxydans CGMCC 1788 on DEAE-52 cellulose, the optimal amount of enzyme protein was 12 mg protein: 1 g DEAE-52 cellulose; the optimal pH was 6.5; and the optimal immobilization time was 6 hr. The specific activity of immobilized enzyme was 36.67 mU.g-1 carrier with an immobilization yield of ...
Liu, Guiyou +9 more
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