Results 31 to 40 of about 8,591 (223)

Nrf2 Is a Key Regulator on Puerarin Preventing Cardiac Fibrosis and Upregulating Metabolic Enzymes UGT1A1 in Rats

open access: yesFrontiers in Pharmacology, 2018
Puerarin is an isoflavone isolated from Radix puerariae. Emerging evidence shown that puerarin possesses therapeutic benefits that aid in the prevention of cardiovascular diseases.
Shao-Ai Cai   +12 more
doaj   +1 more source

Puerarin specifically disrupts osteoclast activation via blocking integrin-β3 Pyk2/Src/Cbl signaling pathway

open access: yesJournal of Orthopaedic Translation, 2022
Objective: Given the limitations of current anti-resorption agents for postmenopausal osteoporosis, there is a need for alternatives without impairing coupling crosstalk between bone resorption and bone formation ie. osteoclastogenesis.
Zuocheng Qiu   +11 more
doaj   +1 more source

Samsoeum, a traditional herbal medicine, elicits apoptotic and autophagic cell death by inhibiting Akt/mTOR and activating the JNK pathway in cancer cells [PDF]

open access: yes, 2013
BACKGROUND: Samsoeum (SSE), a traditional herbal formula, has been widely used to treat cough, fever, congestion, and emesis for centuries. Recent studies have demonstrated that SSE retains potent pharmacological efficiency in anti-allergic and anti ...
Aeyung Kim, Jin Yeul Ma, Nam-Hui Yim
core   +1 more source

Chronopharmacokinetics of puerarin in diabetic rats

open access: yesIndian Journal of Pharmaceutical Sciences, 2013
Puerarin injection has been widely used for clinic treatment of diabetes recently. To assess the relationship between the administration time of puerarin and the blood concentration of puerarin as well as its pharmacokinetic parameters, the diabetic rat model was used in current study.
Zhang, C. T.   +4 more
openaire   +3 more sources

Puerarin attenuates pressure overload-induced cardiac hypertrophy [PDF]

open access: yesJournal of Cardiology, 2014
Puerarin is the most abundant isoflavonoid in kudzu root. It has been used to treat angina pectoris and myocardial infarction clinically. However, little is known about the effect of puerarin on cardiac hypertrophy.Aortic banding (AB) was performed to induce cardiac hypertrophy in mice. Puerarin premixed in diets was administered to mice after one week
Yuan, Yuan   +9 more
openaire   +2 more sources

Puerarin-Hericium Insoluble Dietary Fiber Compound Preparation of Microcapsule and Study of the Physical and Chemical Properties

open access: yesShipin gongye ke-ji
Objective: To prepare puerarin-Hericium insoluble dietary fiber composite microcapsules, and promote the research and development of puerarin related products by improving its embedding rate, antioxidant properties and bioaccessibility. Methods: Puerarin
Maolin LI   +6 more
doaj   +1 more source

Puerarin attenuates hypoxia-resulted damages in neural stem cells by up-regulating microRNA-214

open access: yesArtificial Cells, Nanomedicine, and Biotechnology, 2019
Puerarin has been reported to be useful in protection against hypoxia-induced injury. In our current study, we attempted to explore the protective effects of puerarin against hypoxia-caused damages in neural stem cells (NSCs).
Baoying Wang, Wenna Ma, Huiyu Yang
doaj   +1 more source

Advances in isoflavone profile characterisation using matrix solid-phase dispersion coupled to HPLC/DAD in medicago species [PDF]

open access: yes, 2015
Analytical methods used in phytochemistry analysis are limited by the sample preparation step, which should ideally be fast, accurate, ecofriendly and achievable using low quantities of the sample.
Barreira, João C.M.   +5 more
core   +1 more source

Effects of dietary puerarin on growth, digestive enzyme, antioxidant capacity, immune and liver health of Acanthopagrus latus

open access: yesAquaculture Reports
This study was conducted to investigate the effects of puerarin on growth, digestive enzymes, antioxidant capacity, immunity and liver health of Acanthopagrus latus. Four diets were formulated: a control diet (C) and C supplemented with 200, 400, and 600 
Jianrong Ma   +12 more
doaj   +1 more source

Current Status of Herbal Medicines in Chronic Liver Disease Therapy: The Biological Effects, Molecular Targets and Future Prospects [PDF]

open access: yes, 2015
Chronic liver dysfunction or injury is a serious health problem worldwide. Chronic liver disease involves a wide range of liver pathologies that include fatty liver, hepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma.
Feng, Y   +5 more
core   +2 more sources

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