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Long‐chain PUFA supplementation improves PUFA profile in infants with cholestasis

Lipids, 2002
AbstractLong‐chain PUFA (LCP) deficiency is a frequent complication in cholestatic infants. We investigated the effects of LCP‐supplemented formula on EFA status in infants with cholestasis. Twenty‐three infants with cholestasis (biliary atresia after surgery, 8; intrahepatic cholestasis, 15) aged 1.9 to 4.9 mon (median 3.1 mon) were randomized to ...
Piotr, Socha   +7 more
openaire   +2 more sources

n-3 PUFA and lipotoxicity

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2010
Excess lipid accumulation in nonadipose tissues may occur in the setting of high levels of plasma free fatty acids or triglycerides (TGs) in a process called "lipotoxicity". Evidence from human studies and animal models suggests that lipid accumulation in the heart, skeletal muscle, pancreas, and liver play an important role in the pathogenesis of ...
Pablo, Perez-Martinez   +2 more
openaire   +2 more sources

Omega-3-PUFA, Omega-6-PUFA and Mitochondria

2008
Omega-3 and omega-6 polyunsaturated fatty acids (PUFAs) belong to the essential fatty acids because the body cannot synthesize them and they must be obtained from the diet. That is why the role of the diet in prevention of mitochondrial damage and pathogenesis of hypertension, coronary artery disease, type 2 diabetes and atherosclerosis has been ...
Anna Gvozdjáková   +4 more
openaire   +1 more source

Long Chain n-3 PUFA Content and n-6/n-3 PUFA Ratio in Mammal, Poultry and Fish Muscles Largely Explain Differential Protein and Lipid Oxidation Profiles Following in vitro Gastrointestinal Digestion.

Molecular Nutrition & Food Research, 2019
SCOPE Muscle food characteristics (fatty acid profile, heme-Fe, intrinsic antioxidants) that relate to the formation of (patho)physiological oxidation products during gastrointestinal digestion were investigated.
Thomas Van Hecke   +3 more
semanticscholar   +1 more source

Whole‐body utilization of n−3 PUFA in n−6 PUFA‐deficient rats

Lipids, 2003
AbstractWe evaluated the utilization of α‐linolenic acid (18∶3n−3) in growing rats consuming a diet deficient in n−6 PUFA. After 90 d, whole‐body 18∶3n−3 accumulation was 55% lower, total n−3 PUFA accumulation was 21% lower, and 18∶3n−3 disappearance was 14% higher in n−6 PUFA‐deficient rats.
Richard P, Bazinet   +2 more
openaire   +2 more sources

Algae and omega-3 PUFAs

Medical alphabet, 2022
Nutrition plays a critical role in health promotion and disease prevention, while nutrition-related factors are in many cases key risk factors contributing to morbidity and mortality. The “modern” diet is increasingly leading to health problems such as overweight and obesity, type 2 diabetes, some types of cancer, neurodegenerative and other diseases ...
E. V. Prokopenko   +2 more
openaire   +1 more source

n−3 PUFAs in cardiovascular disease

International Journal of Cardiology, 2013
Many large, randomised clinical trials and some meta-analyses have shown that treatment with n-3 polyunsaturated fatty acids (n-3 PUFAs) is associated with consistent benefits on cardiovascular (CV) events, primarily due to a reduction of coronary and CV deaths in patients with coronary heart disease.
Roberto, Marchioli, Giacomo, Levantesi
openaire   +2 more sources

n-3 PUFAs and heart failure

International Journal of Cardiology, 2013
The risk of death of patients with heart failure (HF) is still too high in daily clinical practice despite the many progress that have occurred in the diagnosis and treatment of this syndrome that significantly reduce the mortality of these patients.
Roberto, Marchioli, Giacomo, Levantesi
openaire   +2 more sources

Correlation between PUFA/pufa scores and BMI-for age in rural Indian children

Indian Journal of Oral Sciences, 2014
Context: Dental caries continues to be a major health problem in the developing nations like India. The unmet dental care needs pose an important risk factor for undernutrition prevalence in rural areas. Aims: The present study aimed to investigate the effect of dental caries and its consequences using pulp involvement, ulceration, fistula, abscess ...
Devinderjit Kaur   +3 more
openaire   +1 more source

The Influence of n‐3 PUFA Supplements and n‐3 PUFA Enriched Foods on the n‐3 LC PUFA Intake of Flemish Women

Lipids, 2010
AbstractFood consumption data of Flemish women of reproductive age collected in 2002 showed a large deficit for ALA and n‐3 LC PUFA compared to the recommendations (mean ALA and EPA + DHA intake 1.4 g/day and 209 mg/day, respectively) and indicated a need to tackle the problem of low n‐3 PUFA intake.
Isabelle, Sioen   +4 more
openaire   +2 more sources

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