Results 161 to 170 of about 8,097,471 (281)

Metabolic and blood flow responses to single leg emphasis cycling compared to single and double leg cycling

Experimental Physiology, EarlyView.
Abstract Single leg emphasis cycling (SLEC) has the potential to be beneficial in the rehabilitation setting; however, the metabolic responses to it are unknown. Thus, the current investigation sought to evaluate the metabolic and blood flow responses of SLEC compared to traditional double leg cycling (DLC) and single leg cycling (SLC).
B. Ryan Davis, Shane Aultman, Safwan Barnawi, Alex Sipolino, John McDaniel   +4 more
wiley   +1 more source

Pharmacological Alteration of Cellular Mechanical Properties in Pulmonary Arterial Smooth Muscle Cells of Idiopathic Pulmonary Arterial Hypertension. [PDF]

Cardiol Res, 2021
Katsuragi S, Tatsumi N, Matsumoto M, Narita J, Ishii R, Suginobe H, Tsuru H, Wang R, Kogaki S, Tanaka R, Ozono K, Okajima T, Ishida H.   +12 more
europepmc   +1 more source

Lifestyle modification in atrial fibrillation: Mechanisms, phenotypes and ablation outcomes

Experimental Physiology, EarlyView.
Abstract Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia and is associated with significant morbidity, mortality and healthcare utilization. Catheter ablation is increasingly used as a rhythm‐control intervention for patients with symptomatic paroxysmal and persistent AF, yet recurrence rates remain suboptimal.
Konstantinos Grigoriou, Paschalis Karakasis, Panagiotis Theofilis, Konstantinos Pamporis, Panayotis K. Vlachakis, Anastasios Apostolos, Nikolaos Ktenopoulos, Barbara Fyntanidou, Efstratios Karagiannidis, Dimitrios Patoulias, Antonios P Antoniadis, Nikolaos Fragakis   +11 more
wiley   +1 more source

Pulmonary arterial mechanoreceptors mediate sustained sympathoexcitation during high altitude hypoxia in humans

Experimental Physiology, EarlyView.
Abstract Sympathetic nervous system activation is a hallmark of high‐altitude hypoxia, yet the afferent mechanisms remain incompletely defined. We examined the relative contributions of pulmonary arterial mechanoreceptors and carotid chemoreceptors – two excitatory pathways co‐activated by hypoxia – to sustained sympathoexcitation at altitude.
Michiel T. Ewalts, Lydia L. Simpson, Jack S. Talbot, Elliott J. Jenkins, Travis D. Gibbons, Connor A. Howe, Lauren E. Maier, Emily R. Vanden Berg, Alex M. Williams, Philip N. Ainslie, Samuel J. Oliver, Craig D. Steinback, Mike Stembridge, Jonathan P. Moore   +13 more
wiley   +1 more source

MicroRNA‑153 attenuates hypoxia‑induced excessive proliferation and migration of pulmonary arterial smooth muscle cells by targeting ROCK1 and NFATc3. [PDF]

Mol Med Rep, 2021
Zhao M, Wang W, Lu Y, Wang N, Kong D, Shan L.   +5 more
europepmc   +1 more source

A comparison of the neuromuscular, cardiopulmonary and muscle oxygenation responses to single‐ and double‐leg cycling in older adults

Experimental Physiology, EarlyView.
Abstract Previous work in younger adults has shown that during small muscle mass exercise, the tolerable degree of neuromuscular impairment at task failure is greater than during large muscle mass exercise. However, no study has compared the neuromuscular responses to small and large muscle mass exercise whilst matching exercise modality in older ...
Emily Dodd, Callum G. Brownstein
wiley   +1 more source

Adenylate Kinase 4-A Key Regulator of Proliferation and Metabolic Shift in Human Pulmonary Arterial Smooth Muscle Cells via Akt and HIF-1α Signaling Pathways. [PDF]

Int J Mol Sci, 2021
Wujak M, Veith C, Wu CY, Wilke T, Kanbagli ZI, Novoyatleva T, Guenther A, Seeger W, Grimminger F, Sommer N, Schermuly RT, Weissmann N.   +11 more
europepmc   +1 more source

Mechanism of the inhibition of Ca2+-activated Cl- currents by phosphorylation in pulmonary arterial smooth muscle cells [PDF]

, 2006
Greenwood, IA, Amy R. Sanguinetti, Leblanc, N, Iain A. Greenwood, Kenyon, JL, Jeff E. Angermann, Sanguinetti, AR, James L. Kenyon, Normand Leblanc, Angermann, JE   +9 more
core   +1 more source

Pressure‐dependent coupling between arterial pressure and intercostal muscle blood‐flow index during acute hypotension in humans

Experimental Physiology, EarlyView.
Abstract Regulation of respiratory muscle blood flow during acute systemic hypotension remains poorly understood in humans because continuous assessment of microvascular perfusion during rapid haemodynamic transients has been technically challenging. Using diffuse correlation spectroscopy, we investigated second‐by‐second coupling between mean arterial
Masashi Ichinose, Mikie Nakabayashi, Yumie Ono   +2 more
wiley   +1 more source

Geniposide protects pulmonary arterial smooth muscle cells from lipopolysaccharide-induced injury via α7nAchR-mediated TLR-4/MyD88 signaling. [PDF]

Exp Ther Med, 2021
Shen SY, Ren LQ, Chen HD, Zhu HF, Zhou DF, Zhang B, Tan XQ, Xie YH.   +7 more
europepmc   +1 more source