Results 191 to 200 of about 8,097,471 (281)

TCF7 enhances pulmonary hypertension by boosting stressed natural killer cells and their interaction with pulmonary arterial smooth muscle cells. [PDF]

Respir Res
Wu LW, Chen M, Jiang DJ, Jiang CY, Liu YW, Feng B, Shi CF, Huang X, Zhang X, Xu XH, Zhou XL, Shen Y, Liu TY, Ye LC, He YY, Zhang H, Yan Y.   +16 more
europepmc   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

The Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer, Wafa Douzi, Johannes Burtscher   +2 more
wiley   +1 more source

Proteasome inhibitor bortezomib prevents proliferation and migration of pulmonary arterial smooth muscle cells. [PDF]

Kaohsiung J Med Sci
Liu YC, Tseng YH, Kuan YH, Wang LY, Huang SE, Tsai SP, Yeh JL, Hsu JH.   +7 more
europepmc   +1 more source

Protein kinase signaling in hypertensive pulmonary arterial smooth muscle

, 2006
The signaling mechanisms defining the role of protein kinases in pulmonary vascular physiology regulation is an area of great interest. Normally, signaling mechanisms which elevate cyclic AMP (cAMP) and cyclic GMP (cGMP) maintain the pulmonary ...
Zhu, Shu, Barman, Scott A., White, Richard E.   +2 more
core  

Hypoxia and the cytoskeleton

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source

[Silencing DDX17 inhibits proliferation and migration of pulmonary arterial smooth muscle cells <i>in vitro</i> by decreasing mTORC1 activity]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Deng X, Wang J, Xiong M, Wang T, Yang Y, Li, Sun X.   +6 more
europepmc   +1 more source

Human placental exposure to pollutant nanoparticles: uptake, translocation and functional impact

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to pollutant nanoparticles has been increasingly investigated due to concerns about their potential effects on placental function and pregnancy outcomes. Maternal inhalation of pollutant nanoparticles can result in a pro‐inflammatory response; particles can also translocate across the alveolus epithelial barrier
Katherine L. Bethell, Andrew C. Povey, Edward D. Johnstone, Peter T. Ruane   +3 more
wiley   +1 more source

Long‐term passive heat acclimation enhances maximal oxygen consumption via haematological and cardiac adaptation in endurance runners

The Journal of Physiology, EarlyView.
Abstract Figure Legend Endurance‐trained runners completed a 5‐week hot‐water‐immersion (HWI) intervention (≥40°C, 45 min, five sessions per week) and a training‐matched control period in a cross‐over design. HWI induced a 33 g increase in haemoglobin mass (Hbmass) and a 10 mL expansion in left‐ventricular end‐diastolic volume (LVEDV), resulting in a 2.
Elliott J. Jenkins, Joseph A. Killick, Owain Zerilli, Andrew J. M. Douglas, Liam Corr, Michael G. Hughes, Joshua C. Tremblay, Mike Stembridge   +7 more
wiley   +1 more source

Elevational variation in heart mass and suppression of hypoxia‐induced right ventricle hypertrophy in Andean leaf‐eared mice (Phyllotis)

The Journal of Physiology, EarlyView.
Abstract figure legend In lowland mammals that ascend to high elevation, hypoxia‐induced changes in the pulmonary circulation can give rise to hypoxic pulmonary hypertension (HPH) and associated right‐ventricle (RV) hypertrophy. Andean mice with broad elevational ranges have greater heart mass relative to body size at higher elevations, but they ...
Naim M. Bautista, Nathanael D. Herrera, Marcial Quiroga‐Carmona, Chandrasekhar Natarajan, Adriana Rico‐Cernohorska, Jorge Salazar Bravo, Graham R. Scott, Guillermo D'Elía, Zachary A. Cheviron, Jay F. Storz   +9 more
wiley   +1 more source

[The Effects of Ginsenoside Compound K on PDGF-BB-Induced PASMCs Proliferation and Phenotypic Conversion of Pulmonary Arterial Smooth Muscle Cells]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban, 2021
Liu T, Xie L, Liu HM, Liu B.
europepmc   +1 more source