Results 1 to 10 of about 209,598 (340)

Purine Phosphoribosyltransferases [PDF]

Journal of Biological Chemistry, 2000
S P, Craig, A E, Eakin
openaire   +2 more sources

Synthesis, Antiproliferative Activity, and ADME Profiling of Novel Racemic and Optically Pure Aryl-Substituted Purines and Purine Bioisosteres

Biomolecules
The aim of this study was to synthesize new racemic and optically pure aryl-substituted purine bioisosteres using ultrasound-assisted Cu(I)-catalyzed Huisgen 1,3-dipolar cycloaddition.
Martina Piškor, Astrid Milić, Sanja Koštrun, Maja Majerić Elenkov, Petra Grbčić, Sandra Kraljević Pavelić, Krešimir Pavelić, Silvana Raić-Malić   +7 more
doaj   +1 more source

Probiotics administration alleviates cognitive impairment and circadian rhythm disturbance induced by sleep deprivation

Food Science and Human Wellness
Gut microbiome is indispensable for maintaining normal brain function. Specifically, gut microbiota plays a causal role in sleep deprivation (SD)-induced cognitive impairment.
Peijun Tian, Yunfei Hou, Zheng Wang, Jiaona Jiang, Xin Qian, Zhihao Qu, Jianxin Zhao, Gang Wang, Wei Chen   +8 more
doaj   +1 more source

5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-Monophosphate (AICAR), a Highly Conserved Purine Intermediate with Multiple Effects

Metabolites, 2012
AICAR (5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate) is a natural metabolic intermediate of purine biosynthesis that is present in all organisms.
Bertrand Daignan-Fornier, Benoît Pinson
doaj   +1 more source

Effects of Different Packaging on the Purine Content and Key Enzymes of Refrigerated Yellow Croaker (Larimichthys crocea)

Foods
In this study, we investigated the effects of air packaging, vacuum packaging and modified atmosphere packaging (CO2/N2: 80/20) on the purine metabolism and enzyme activities of refrigerated large yellow croakers.
Tiansheng Xu, Wenxuan Lu, Bohan Chen, Dapeng Li, Jing Xie   +4 more
doaj   +1 more source

Use of dried brewers' grains instead of soybean meal to feed lactating cows

Revista Brasileira de Zootecnia
The objective of this study was to determine the optimal level of dried brewers' grains (DBG) to replace soybean meal in diets for lactating Holstein cows.
Andressa Faccenda, Maximiliane Alavarse Zambom, Deise Dalazen Castagnara, André Sanches de Avila, Tatiane Fernandes, Everline Inês Eckstein, Fernando Andre Anschau, Cibele Regina Schneider   +7 more
doaj   +1 more source

Heterocyclic Nitrogen Compounds as Potential PDE4B Inhibitors in Activated Macrophages

Applied Sciences
Cyclic-nucleotide phosphodiesterases (PDEs) represent a superfamily of enzymes playing a pivotal role in cell signaling by controlling cAMP and cGMP levels in response to receptor activation.
Simona Todisco, Vittoria Infantino, Anna Caruso, Anna Santarsiero, Paolo Convertini, Hussein El-Kashef, Federica Giuzio, Maria Stefania Sinicropi, Carmela Saturnino   +8 more
doaj   +1 more source

The parallel accumulation and distribution of two purine-oxidizing enzymes during frog development [PDF]

, 2012
Dennis Barrett
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Gene Expression Analysis of HPRT-Deficient Cells Maintained with Physiological Levels of Folic Acid

Cells
Lesch–Nyhan disease (LND) is associated with a complete deficiency of hypoxanthine-guanine phosphoribosyltransferase (HPRT) activity due to mutations in the HPRT1 gene.
Rosa J. Torres, Gerard Valentines-Casas, Claudia Cano-Estrada, Neus Ontiveros, José M. López   +4 more
doaj   +1 more source

Synthesis and Application of Purine-Based Fluorescence Probe for Continuous Recognition of Cu 2+ and Glyphosate

, 2023
Xu Chen, Yanxia Mao, Anguan Wang, Linchuan Lu, Qi Shao, Chunhui Jiang, Hongfei Lu   +6 more
openalex   +1 more source