Results 111 to 120 of about 151,646 (288)
Construction of Chronic Kidney Disease Mouse Model Induced by Diets With Different Adenine Content
Food Safety and Health, EarlyView.By administering a 4 weeks adenine diet to C57BL/6J mice, we identified 0.2% adenine in purified feed as the optimal chronic kidney disease model. This model induces severe renal damage, gut dysbiosis, uremic toxin accumulation, and CKD mineral bone disorder, providing a clinically relevant platform for mechanistic and therapeutic studies.
Wanjun Liao +8 more
wiley +1 more source
Purines. VII. 1-Alkoxy-9-alkyladenine Salts as Possible Alkylating Reagents
, 1972 Tozo Fujii, T. ITAYA, SATOSHI MORO
openalex +2 more sources
Correction: Application of Crystallographic and Modeling Methods in the Design of Purine Nucleoside Phosphorylase Inhibitors [PDF]
, 1992 S. E. Ealick
openalex +1 more source
Monosaccharide‐Based Macrocyclic Receptors—History and Recent Applications
Helvetica Chimica Acta, EarlyView.This perspective provides an overview of most common applications of monosaccharide‐based macrocycles in molecular recognition over the past four decades. The most recent achievements, such as fluorescent ion sensing and selective amino acid binding in aqueous media, including the work from the author's lab, are highlighted. Potential future directions
Bartosz Lewandowski
wiley +1 more source
iMetaMed, EarlyView.The occurrence and progression of colorectal cancer are intricately linked to metabolites produced by the gut microbiota. Metabolites generated by pathogenic microbial communities can promote colorectal cancer development by reshaping the immune microenvironment.
Xinrui Yang +3 more
wiley +1 more source
iMetaOmics, EarlyView.Our study employed an integrated lipidomics and metabolomics approach to elucidate Helicobacter pylori‐driven metabolic perturbations along the gut–brain axis. H. pylori infection was established in gastric epithelial (AGS) cells, and the resulting conditioned media (secretome) was collected and exposed to neuronal (IMR‐32) cells.
Meenakshi Kandpal +4 more
wiley +1 more source