Results 131 to 140 of about 151,646 (288)

Alterations in brain metabolites in rats with experimental periodontitis: A metabolomic approach

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis (PD) is a chronic inflammatory disease with systemic effects. Emerging evidence suggests a link between periodontal inflammation and neurological changes, but the biochemical mechanisms in key brain regions, such as the hippocampus and amygdala, remain unclear.
Ramona Ramalho de Souza Pereira, Caíque Olegário Diniz e Magalhães, Elizabeth Luciana Marinho Miguel, Larissa Vieira Toledo, Débora Ribeiro Orlando, Alan Rodrigues Teixeira Machado, Bruno Del Bianco Borges, Luciano José Pereira, Marco Fabrício Dias‐Peixoto, Eric Francelino Andrade   +9 more
wiley   +1 more source

CpRu Complexes Containing Water Soluble Phosphane PTA and Natural Purines Adenine, Guanine and Theophylline: Synthesis, Characterization, and Antiproliferative Properties

, 2019
Lazhar Hajji, Cristobal Saraiba‐Bello, Gaspar Segovia‐Torrente, Franco Scalambra, Antonio Romerosa   +4 more
openalex   +2 more sources

Warfarin-Durian interaction: A case study bridging clinical outcomes and metabolic profiling through metabolomics. [PDF]

Toxicol Rep
Hiranchatchawal N, Wannaphueak K, Rattanasuwan P, Lertpongpipat P, Konguthaithip G, Jaikang C, Tajai P.   +6 more
europepmc   +1 more source

PERCC1‐associated enteropathy: Diagnostic challenges and enteral autonomy achieved with teduglutide

JPGN Reports, EarlyView.
Abstract Congenital diarrheas and enteropathies (CODE) are rare inherited disorders characterized by early‐onset intractable diarrhea. Though progress has been made in elucidating the genetic basis of CODE, much remains to be discovered. Another challenge is the lack of curative therapies—treatment is primarily supportive including enteral and ...
Angela Tran, Vivien Nguyen, Phuong Huynh
wiley   +1 more source

New Pyrrolo[2,1-f]purine-2,4-dione and Imidazo[2,1-f]purine-2,4-dione Derivatives as Potent and Selective Human A₃ Adenosine Receptor Antagonists

, 2005
Pier Giovanni Baraldi, Delia Preti, Mojgan Aghazadeh Tabrizi, Francesca Fruttarolo, Romeo Romagnoli, Naser Abdel Zaid, Allan R. Moorman, Stefania Merighi, Katia Varani, Pier Andrea Borea   +9 more
openalex   +1 more source

Effect of Purine and Pyrimidine Analogues on Growth and RNA Metabolism in the Soybean Hypocotyl-the Selective Action of 5-Fluorouracil [PDF]

, 1966
Joe L. Key
openalex   +1 more source

Identification of Natural and Artificial Modifications in DNA at the Nanometer Level

Journal of Raman Spectroscopy, EarlyView.
Short single‐ and double‐stranded DNA sequences with natural and artificial markers are examined at ambient conditions using TERS to identify and localize the labelled nucleobases. The differences between single‐ and double‐stranded DNA should provide clear experimental evidence of the extreme surface sensitivity of TERS.
Tanja Deckert‐Gaudig, Prabha Singh, Miklos Veres, Roman Holomb, Volker Deckert   +4 more
wiley   +1 more source

IMP metabolic mechanisms and IMPDH targeting strategies in tumor metabolic reprogramming and therapy (Review). [PDF]

Int J Mol Med
Zhu H, Wang H, Li X, Zhang W, Wang Y, Tan Q, Ying D, Shi Z, Song J.   +8 more
europepmc   +1 more source

Effects of catechins, resveratrol, silymarin components and some of their conjugates on xanthine oxidase‐catalyzed xanthine and 6‐mercaptopurine oxidation

Journal of the Science of Food and Agriculture, Volume 105, Issue 5, Page 2765-2776, 30 March 2025.
Abstract BACKGROUND Over the past two decades, the global incidence of gout has markedly increased, affecting people worldwide. Considering the side effects of xanthine oxidase (XO) inhibitor drugs (e.g. allopurinol and febuxostat) used in the treatment of hyperuricemia and gout, the potential application of phytochemicals has been widely studied.
Tímea Bencsik, Orsolya Balázs, Róbert G Vida, Balázs Z Zsidó, Csaba Hetényi, Kateřina Valentová, Miklós Poór   +6 more
wiley   +1 more source

Synthesis and characterization of azanonaborane-containing purine derivatives for boron neutron capture therapy

Open Chemistry, 2008
Genady Afaf, El-Zaria Mohamed, Gabel Detlef   +2 more
doaj   +1 more source