Results 131 to 140 of about 187,335 (337)

Characterization of the pattern of development of key compounds contributing to aroma quality of chicken meat and their metabolic markers

Animal Research and One Health, EarlyView.
The graphical abstract shows the principal results of this study. Eight major aroma‐contributing compounds (nonanal, octanal, dimethyl tetrasulfide, hexanal, 1‐octen‐3‐ol, (E)‐2‐nonenal, heptanal, and (E,E)‐2,4‐decadienal) were identified by electronic nose and GC‐O‐MS analysis, and their content increased with age.
Yanke Wang, Xiaojing Liu, Yongli Wang, Zhengxiao He, Guiping Zhao, Jie Wen, Huanxian Cui   +6 more
wiley   +1 more source

BIOSYNTHESIS OF THE PURINES

, 1957
Leonard Warren, John M. Buchanan
openalex   +2 more sources

Synthesis, Antiproliferative Activity, and ADME Profiling of Novel Racemic and Optically Pure Aryl-Substituted Purines and Purine Bioisosteres

Biomolecules
The aim of this study was to synthesize new racemic and optically pure aryl-substituted purine bioisosteres using ultrasound-assisted Cu(I)-catalyzed Huisgen 1,3-dipolar cycloaddition.
Martina Piškor, Astrid Milić, Sanja Koštrun, Maja Majerić Elenkov, Petra Grbčić, Sandra Kraljević Pavelić, Krešimir Pavelić, Silvana Raić-Malić   +7 more
doaj   +1 more source

Mechanisms of Synthesis of Purine Nucleotides in Heart Muscle Extracts1 [PDF]

, 1957
David A. Goldthwait
openalex   +1 more source

Pharmacogenomics in the UK National Health Service: Progress towards implementation

British Journal of Clinical Pharmacology, EarlyView.
Over the past decade there has been considerable and growing enthusiasm about the promise of using genomics to inform healthcare. In particular, using genetic data to inform prescribing practice has emerged as a compelling policy priority for health systems around the world, not least in the NHS.
John H. McDermott, Maria Tsakiroglou, William G. Newman, Munir Pirmohamed   +3 more
wiley   +1 more source

Probiotics administration alleviates cognitive impairment and circadian rhythm disturbance induced by sleep deprivation

Food Science and Human Wellness
Gut microbiome is indispensable for maintaining normal brain function. Specifically, gut microbiota plays a causal role in sleep deprivation (SD)-induced cognitive impairment.
Peijun Tian, Yunfei Hou, Zheng Wang, Jiaona Jiang, Xin Qian, Zhihao Qu, Jianxin Zhao, Gang Wang, Wei Chen   +8 more
doaj   +1 more source

N‐ to C‐Glycoside Rearrangement of Uridine 5′‐Phosphate in Two Enzymatic Steps for the Production of Pseudouridine 5′‐Phosphate

Biotechnology and Bioengineering, EarlyView.
The authors present a streamlined cascade reaction for one‐pot N‐C rearrangement of uridine‐5′‐phosphate (UMP) to pseudouridine‐5′‐phosphate (ΨMP; a key mRNA vaccine building block), in two enzymatic steps catalyzed by UMP nucleosidase (EC 3.2.2.10) and ΨMP C‐glycosidase (EC 4.2.1.70).
Martin Pfeiffer, Franziska Guld, Bernd Nidetzky   +2 more
wiley   +1 more source

Nucleoside Analogues for Chagas Disease and Leishmaniasis Therapy: Current Status and Future Perspectives

Molecules
Chagas disease and leishmaniasis are two neglected tropical diseases that affect millions of people in low- and middle-income tropical countries. These diseases caused by protozoan parasites pose significant global health challenges, which have been ...
Emmanuel Awucha Nwoke, Silvester Lowe, Fawaz Aldabbagh, Karunakaran Kalesh, Hachemi Kadri   +4 more
doaj   +1 more source

Tailored Watson–Crick Pairing Partners for Xanthosine in RNA

Chemistry – A European Journal, Volume 31, Issue 42, July 25, 2025.
RNAs with kappa‐xanthosine (K–X) or 2‐iminocytidine‐xanthosine (2imC–X) base pairs form stable double helices that have higher melting temperatures than those of the A–U or G–U references. Access to these novel 2imC‐modified RNAs is possible through the mild, selective chemical conversion of 2‐thiocytidine RNA precursors.
Stefan Mair, Anna Rázková, Karl Brillet, Catherina Gasser, Eric Ennifar, Ronald Micura   +5 more
wiley   +1 more source

Insights into the Molecular Mechanisms of Purine Compounds Synergistically Inducing Larval Settlement in Mytilopsis sallei Using Multi-Group Comparative Transcriptomic Analysis

Biology
Most benthic marine invertebrates exhibit a characteristic biphasic life cycle, consisting of a planktonic larval stage followed by a benthic adult stage [...]
Jian He, Huanhuan Hao, Huakang Pan, Shanshan Yao, Yiran Zhao, Shifeng Guo, Jianfang Huang, Danqing Feng   +7 more
doaj   +1 more source