Results 131 to 140 of about 209,598 (340)

Purine nucleoside analogs: emerging roles in indolent lymphoproliferative disorders [published erratum appears in Blood 1996 Mar 1;87(5):2093] [PDF]

, 1995
MS Tallman, D Hakimian
openalex   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Characterization of Guanine Deaminase from Kluyveromyces marxianus and Its Industrial Application to Reduce Guanine Content in Beer

Foods
Guanine deaminase (GDA) catalyzes the first step in purine catabolism by converting guanine to xanthine. Despite its significant role in the development of low-purine food, studies on GDA remain limited compared to other metabolic deaminases. To identify
Peng Zhou, Junhao Xu, Zixuan Wang, Baoguo Li, Zhijun Zhao   +4 more
doaj   +1 more source

Pyrazolo[1,5-a]-1,3,5-triazine as a Purine Bioisostere: Access to Potent Cyclin-Dependent Kinase Inhibitor (R)-Roscovitine Analogue

, 2009
Florence Popowycz, Guy Fournet, Cédric Schneider, Karima Bettayeb, Yoan Ferandin, Cyrile Lamigeon, Òscar M. Tirado, Silvia Mateo‐Lozano, Vicente Notario, Pierre Colas, Philippe Bernard, Laurent Meijer, Benoı̂t Joseph   +12 more
openalex   +1 more source

Supplementary Figure 1 from A Purine Scaffold HSP90 Inhibitor BIIB021 Has Selective Activity against KSHV-Associated Primary Effusion Lymphoma and Blocks vFLIP K13-Induced NF-κB [PDF]

, 2023
Gopalakrishnan Ramakrishnan, Hittu Matta, Preet M. Chaudhary   +2 more
openalex   +1 more source

Protective Effects of Auricularia auricula Polysaccharides on Acute Lung Injury by Regulating Intestinal Flora and Metabolism

Food Frontiers, EarlyView.
Auricularia auricula polysaccharides (AAP; 100, 200, and 400 mg/kg) protect against acute lung injury (ALI) by dose‐dependently remodeling the gut microbiota and modulating associated metabolic pathways via the gut‐lung axis, thereby enhancing pulmonary anti‐inflammatory and antioxidant capacity to ultimately prevent tissue damage.
Haili Niu, Fangjia Zhao, Qi Wang, Min Li, Yuan Li, Ivan Kurtovic, Zitong Zhang, Yahong Yuan, Tianli Yue   +8 more
wiley   +1 more source

Insights into the Molecular Mechanisms of Purine Compounds Synergistically Inducing Larval Settlement in Mytilopsis sallei Using Multi-Group Comparative Transcriptomic Analysis

Biology
Most benthic marine invertebrates exhibit a characteristic biphasic life cycle, consisting of a planktonic larval stage followed by a benthic adult stage [...]
Jian He, Huanhuan Hao, Huakang Pan, Shanshan Yao, Yiran Zhao, Shifeng Guo, Jianfang Huang, Danqing Feng   +7 more
doaj   +1 more source

A possible role for 5-phosphoribosyl 1-pyrophosphate in the stimulation of uterine purine nucleotide synthesis in response to oestradiol-17β

, 1972
Janet M. Oliver
openalex   +2 more sources

Marine n‐3 Polyunsaturated Fatty Acids Mitigate Obesity Traits Through PRDM16‐Driven Gene–Nutrient Interaction and Spatiotemporal Scale Browning Process

Food Frontiers, EarlyView.
This large cohort study of 45,664 participants from the UK Biobank provides strong epidemiological evidence that fish oil use was associated with 12% and 7% lower risks of obesity and high body fat percentage, respectively. Mechanistically, marine n‐3 polyunsaturated fatty acids mitigate obesity traits through PRDM16‐driven gene–nutrient interactions ...
Xiaohui Liu, Haoyu Li, Youyou Zheng, Xiaoqian Chen, Xuzhi Wan, Pan Zhuang, Wei Jia, Jianxin Yao, Haoyin Liu, Hongbo Shi, Xunan Lin, Yu Zhang, Jingjing Jiao   +12 more
wiley   +1 more source

Mass Spectrometric Analysis of Purine Intermediary Metabolism Indicates Cyanide Induces Purine Catabolism in Rabbits

Metabolites
Purines are the building blocks of DNA/RNA, energy substrates, and cofactors. Purine metabolites, including ATP, GTP, NADH, and coenzyme A, are essential molecules in diverse biological processes such as energy metabolism, signal transduction, and enzyme
Jordan Morningstar, Jangwoen Lee, Sari Mahon, Matthew Brenner, Anjali K. Nath   +4 more
doaj   +1 more source