Results 171 to 180 of about 124,162 (316)

High‐fat diet‐induced obesity augments the deleterious effects of estrogen deficiency on bone: Evidence from ovariectomized mice

open access: yesAging Cell, Volume 21, Issue 12, December 2022., 2022
Obesity in female mice, when combined with estrogen deficiency, has a detrimental impact on bone quality, caused by expansion of bone marrow adiposity, upregulation of pro‐inflammatory markers, upregulation of senescence‐associated phenotype markers and accumulation of senescent cells.
Dalia Ali   +10 more
wiley   +1 more source

Development and Application of Polyphenols in Food: A Comprehensive Review

open access: yesFood Frontiers, EarlyView.
This review provides an in‐depth analysis of functional mechanisms and research trends in the application of polyphenol in food. ABSTRACT This review provides an in‐depth analysis of functional mechanisms and research trends in the application of polyphenol in food.
Yanpei Huang   +7 more
wiley   +1 more source

Guidelines for Studying the Oxidative Stress Damage Model on Drosophila melanogaster

open access: yesFuture Postharvest and Food, EarlyView.
This guideline introduced Drosophila as a research model to summarize in detail the research methods of indicators that can characterize oxidative stress. It generally includes four aspects such as generation of ROS, damage caused by ROS, antioxidant defense, and cell stress repair and apoptosis.
Quanyong Wu
wiley   +1 more source

Moderate hyperuricaemia ameliorated kidney damage in a low‐renin model of experimental renal insufficiency

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 132, Issue 1, Page 21-32, January 2023., 2023
Abstract Uric acid has promoted renal fibrosis and inflammation in experimental studies, but some studies have shown nephroprotective effects due to alleviated oxidative stress. We studied the influence of experimental hyperuricaemia in surgically 5/6 nephrectomized rats. Three weeks after subtotal nephrectomy or sham operation, the rats were allocated
Venla Kurra   +9 more
wiley   +1 more source

PURINE FERMENTATION BY CLOSTRIDIUM CYLINDROSPORUM

open access: hybrid, 1956
Jesse C. Rabinowitz, H.A. Barker
openalex   +1 more source

Novel machine‐learning bioinformatics reveal distinct metabolic alterations for enhanced colorectal cancer diagnosis and monitoring

open access: yesiMetaOmics, EarlyView.
The PANDA pipeline for colorectal cancer (CRC) analysis integrates metabolomic data from LC‐MS with machine learning techniques to classify CRC stages and predict biomarkers. Initially, the raw metabolomic data is processed using partial least squares discriminant analysis (PLS‐DA) to reduce dimensionality and highlight key features.
Rui Xu   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy