Results 181 to 190 of about 1,297,457 (342)
Methotrexate and erythro-9-(2-hydroxynon-3-yl) adenine therapy for rat adjuvant arthritis and the effect of methotrexate on in vivo purine metabolism [PDF]
Joseph E. Baggott, Sarah Morgan
openalex +1 more source
This study used an untargeted metabolomics approach to screen for serum differentially abundant metabolites in colorectal cancer (CRC) patients, and after analyzing a discovery cohort and validation cohort, eight metabolites and their constituent panels were identified as not only having diagnostic value for CRC but also showing value for the early ...
Lugen Zuo+10 more
wiley +1 more source
Synergistic Probiotic-Postbiotic Therapy Ameliorates Hyperuricemia via Multi-Target Regulation of Purine Metabolism and Gut Microbiota. [PDF]
Ren L, Liu S, Wang S, Li Z, Lu F, Luo X.
europepmc +1 more source
Abstract Epilepsy affects approximately 1% of the population worldwide, and although medications are effective in the majority of cases, seizures persist in approximately 30% of patients. Despite the effort to develop new antiseizure drugs, the rate of pharmacoresistance in patients has not diminished over the past 3 decades. There is thus a real unmet
Vincent Magloire+9 more
wiley +1 more source
Opioid use affects antioxidant activity and purine metabolism: preliminary results [PDF]
Paolo Mannelli+5 more
openalex +1 more source
A targeted mass spectrometry‐based metabolomics assay was conducted to identify the impact of stress exposure on the regulation of biological stress pathways in the mdx mouse model of Duchenne muscular dystrophy. We demonstrated a broad shift in the circulating stress‐relevant plasma metabolome associated with stressful scruff handling that was ...
Erynn E. Johnson, James M. Ervasti
wiley +1 more source
Purine metabolism-associated key genes depict the immune landscape in gout patients. [PDF]
Li LN, Wang H, Xiao LS, Lai WN.
europepmc +1 more source