Results 181 to 190 of about 1,297,457 (342)

Discovery‐Replication Strategy Identifies Serum Metabolite Biomarkers for Colorectal Cancer in a Chinese Cohort

open access: yesCancer Science, EarlyView.
This study used an untargeted metabolomics approach to screen for serum differentially abundant metabolites in colorectal cancer (CRC) patients, and after analyzing a discovery cohort and validation cohort, eight metabolites and their constituent panels were identified as not only having diagnostic value for CRC but also showing value for the early ...
Lugen Zuo   +10 more
wiley   +1 more source

Relation between coronary artery stenosis and myocardial purine metabolism, histology and regional function in humans

open access: bronze, 1987
Willem Flameng   +5 more
openalex   +1 more source

WONOEP XVII appraisal: Targeting network excitability beyond the synapse ‐Neurotransmitter, ionic, and electro ‐diffusions

open access: yesEpilepsia, EarlyView.
Abstract Epilepsy affects approximately 1% of the population worldwide, and although medications are effective in the majority of cases, seizures persist in approximately 30% of patients. Despite the effort to develop new antiseizure drugs, the rate of pharmacoresistance in patients has not diminished over the past 3 decades. There is thus a real unmet
Vincent Magloire   +9 more
wiley   +1 more source

Opioid use affects antioxidant activity and purine metabolism: preliminary results [PDF]

open access: green, 2009
Paolo Mannelli   +5 more
openalex   +1 more source

Stress exposure in the mdx mouse model of Duchenne muscular dystrophy provokes a widespread metabolic response

open access: yesThe FEBS Journal, EarlyView.
A targeted mass spectrometry‐based metabolomics assay was conducted to identify the impact of stress exposure on the regulation of biological stress pathways in the mdx mouse model of Duchenne muscular dystrophy. We demonstrated a broad shift in the circulating stress‐relevant plasma metabolome associated with stressful scruff handling that was ...
Erynn E. Johnson, James M. Ervasti
wiley   +1 more source

Assessing gout risk associated with GLP‐1 therapy in obese patients with type 2 diabetes: A retrospective cohort study

open access: yes
Rheumatology &Autoimmunity, EarlyView.
Justin Riley Lam   +6 more
wiley   +1 more source

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