Results 211 to 220 of about 72,751 (304)

Role of S1P‐ and Rho‐kinase signalling in age‐related myogenic tone deficiency in murine resistance arteries

Experimental Physiology, EarlyView.
Abstract Ageing is a risk factor for cardiovascular and neurodegenerative diseases. The myogenic response in resistance arteries is responsible for basal (myogenic) tone and blood flow autoregulation. G‐protein‐coupled receptors and G12/RhoA/Rho kinase are implicated in myogenic tone (MT), and we aimed to clarify their role in pressure sensing and ...
Gry Freja Skovsted, Alex Aupetit, Karl Björling, Kristian Agmund Haanes, Susanne Syberg, Niklas Rye Jørgensen, Blanca I. Aldana, Hirotsugu Tsuchimochi, Mark T. Waddingham, Kristine Freude, James Todd Pearson, Lars Jørn Jensen   +11 more
wiley   +1 more source

Pioglitazone-induced alterations of purine metabolism in healthy male subjects. [PDF]

Clin Transl Sci
Kang J, Li Y, Lee S, Yu KS, Cho JY.
europepmc   +1 more source

308 Transcriptional profiles associated with pericarditis in patients with systemic lupus erythematosus (SLE) identify purine metabolism pathway genes as candidate mediators [PDF]

Olferiev Mikhail, Drogy Madison, Fernandez David, A Kirou Kyriakos, K Crow Mary   +4 more
openalex   +1 more source

Astrocytes: Orchestrators of brain gas exchange and oxygen homeostasis

The Journal of Physiology, EarlyView.
Abstract figure legend Oxygen and carbon dioxide enter the body via breathing; in the brain astrocytes play a key role balancing oxygen delivery with carbon dioxide removal. Abstract If we consider neurons like muscles during exercise, the demand for oxygen (O2) and carbon dioxide (CO2) elimination is constantly changing.
Isabel N. Christie
wiley   +1 more source

Yeast Culture Supplementation Improves Meat Quality by Enhancing Immune Response and Purine Metabolism of Small-Tail Han Sheep (<i>Ovis aries</i>). [PDF]

Int J Mol Sci
Bai X, Wang L, Sun H, Sun L, An J, Fu S, Zhao M, Liu F, Ren X, Liu Z, He J, Liu Y.   +11 more
europepmc   +1 more source

Purine and pyrimidine metabolism of Leishmania mexicana mexicana and other parasitic protozoa. [PDF]

, 1986
Husain F. Hassan
openalex  

MOESM2 of Widespread effect of N-acetyl-d-glucosamine assimilation on the metabolisms of amino acids, purines, and pyrimidines in Scheffersomyces stipitis

, 2018
Kentaro Inokuma, Mami Matsuda, Daisuke Sasaki, Tomohisa Hasunuma, Akihiko Kondo   +4 more
openalex   +1 more source

Targeting ecto‐5′‐nucleotidase (CD73) and cAMP alleviates carotid body hyperactivity and reduces blood pressure in chronically hypoxic rats

The Journal of Physiology, EarlyView.
Abstract figure legend CD73 promotes carotid body hyperactivity in chronically hypoxic animals. Exposure to chronic hypoxia (CH) (FiO2 of 12% for 10 days) increases the proportion of CD73+TH+ cells in the carotid body and induces basal chemoafferent hyperactivity.
Demitris Nathanael, Andrew M. Coney, Dhaifallah Alotaibi, Prem Kumar, Andrew P. Holmes   +4 more
wiley   +1 more source

Common Metabolomic Changes in Various Drug Treatments for Major Depressive Disorder Are Related to Purine Metabolism

Seungyeon Lee, Jiyeong Lee
openalex   +2 more sources

On why cancer cells require a great amount of glucose

Quantitative Biology, Volume 14, Issue 2, June 2026.
Abstract The traditional thinking has been that cancer cells require a great amount of glucose to support their rapid growth, but the reality may be different. We have previously demonstrated that all cancer cells in The Cancer Genome Atlas harbor persistent Fenton reactions in their cytosol, which generate OH− ${\text{OH}}^{-}$ and ultimately kill the
Xuechen Mu, Aoran Liu, Rui Shi, Long Xu, Zhenyu Huang, Ye Zhang, Ying Xu   +6 more
wiley   +1 more source