Results 151 to 160 of about 47,484 (302)
Quantitative analysis of purine nucleotides indicates that purinosomes increase de novo purine biosynthesis. [PDF]
Zhao H +9 more
europepmc +1 more source
ABSTRACT Visceral leishmaniasis (VL) is a human neglected tropical disease in which dogs participate as reservoirs of the etiological agent Leishmania chagasi. The identification of infected dogs is important to the control of VL, and recombinant proteins are strong antigen candidates for canine visceral leishmaniasis (CVL) serodiagnosis. In this work,
Thaís Viana Fialho Martins +12 more
wiley +1 more source
Mosaic nucleic acids that bind purine nucleotides [PDF]
Models for the origin of life have maintained that the first cells relied upon a single biopolymer for both genotype and phenotype. RNA may have provided these activities through its ability to transfer information via base-pairing and its ability to ...
Trevino, Simon Gonzalez
core
Abstract The papaya tree (Carica papaya L.), native to the Americas, is cultivated in tropical regions and holds substantial economic importance, with an estimated export volume of 365 000 t in 2023. However, diseases caused by viruses, fungi, bacteria, and nematodes can lead to severe losses.
Luíza Favaratto +7 more
wiley +1 more source
Structure-guided engineering of a polyphosphate kinase 2 class III from an <i>Erysipelotrichaceae</i> bacterium to produce base-modified purine nucleotides. [PDF]
Mitton-Fry RM +7 more
europepmc +1 more source
A Modular Nucleoside Kinase Cascade for the Synthesis of Ribonucleoside Triphosphates
Damm et al. report standardized enzymatic cascades for production of all canonical nucleoside triphosphates from the corresponding nucleosides, using kinase‐catalyzed phosphorylation from acetyl phosphate. Reactions afforded ∼ 100 mM product in near‐quantitative conversion.
Oliver T. Damm +3 more
wiley +1 more source
Purine Nucleotide Cycles and Their Metabolic Role
B, MAGASANIK, D, KARIBIAN
openaire +2 more sources
Traditional fermented Kimchi “paocai”, commonly consumed in Northeast China, was screened for probiotic resources capable of degrading uric acid in vitro and alleviating hyperuricemia in a mouse model. Abstract Current pharmacological therapies for hyperuricemia (HUA), though effective, pose safety concerns, including allopurinol‐induced severe dermal ...
Aman Khan +8 more
wiley +1 more source
This review provides a comprehensive, engineering‐oriented synthesis of postbiotics as next‐generation functional food ingredients. It first outlines the principal production routes for postbiotic generation, encompassing thermal technologies, non‐thermal technologies, and extraction/purification methods, and subsequently examines the analytical and ...
Tansu Taspinar, Nuray Güzeler
wiley +1 more source
Astrocytic mGluR5 Regulation of Synaptic Transmission is Activity‐Dependent in Adult Rats
In adulthood, astrocytic mGluR5 increases synaptic efficacy through presynaptic A2ARs. This occurs when a small number of synapses are activated simultaneously. This pathway is abolished when numerous synapses are recruited. ABSTRACT Data accumulated over the last two decades have demonstrated that astrocytes play key roles in the regulation of ...
Sarah Mountadem +18 more
wiley +1 more source

