Results 181 to 190 of about 144,015 (298)

Kiss and spit metabolomics highlight the role of host purine metabolism during pathogen infection. [PDF]

mSphere
Gallego-Lopez GM, Olson WJ, Tibabuzo-Perdomo AM, Stevenson D, Amador-Noguez D, Lawrence G, Leahy JW, Contreras Guzman E, Skala MC, Knoll LJ.   +9 more
europepmc   +1 more source

Nucleases and Their Inhibitors: Exploring Biological Roles, Industrial Applications, and Challenges in Heterologous Expression

Biotechnology Journal, Volume 21, Issue 9, September 2026.
Graphical Abstract and Lay Summary Intracellular nucleases, depicted as blue circles in a nucleosome, hydrolyze phosphodiester bonds, repair damaged DNA using DNA base excision repair (BER), mismatch repair (MMR), and homologous recombination (HR), and are involved in DNA replication.
Wian Vermeulen, Anton Du Preez van Staden, Leon M. T. Dicks   +2 more
wiley   +1 more source

Characterization of Gastrointestinal Absorption of Salmon Milt-Derived Oligodeoxyribonucleic Acids in Mice. [PDF]

J Nutr Metab
Hayashi F, Masuo Y, Nishizawa Y, Koike A, Ishimoto T, Kiriyama K, Fujita M, Sutoh K, Kato Y.   +8 more
europepmc   +1 more source

Adaptive Genomic Divergence Across Altitudes in Capsella bursa‐pastoris

Biological Diversity, Volume 3, Issue 3, Page 125-135, September 2026.
Genomic divergence was observed between high‐altitude and low‐altitude populations of Capsella bursa‐pastoris in China, consistent with an important role of ecological factors. Candidate adaptive loci associated with enhanced energy metabolism, photoprotection, and growth plasticity under altitudinal stress were identified.
Lu Liu, Jia Li, Xin Liu, Xue‐Jun Ge, Hui‐Run Huang   +4 more
wiley   +1 more source

The oncogenic control of nucleotide synthesis. [PDF]

Oncogenesis
Vidal-Cruchez O, Ben-Sahra I.
europepmc   +1 more source

Derivatives of 2,6-Diazidopurine and 2,6-Bis-(1,2,3-Triazol-1-yl) Purine as Useful Intermediates in the Synthesis of Modified Purine Nucleosides

Novel 2,6-bis-(1,2,3-triazol-1-yl)purine, N6-substituted-2-(1,2,3-triazol-1-yl)adenine and 6-alkyl/arylthio-2-(1,2,3-triazol-1-yl)purine and 2-alkylthio-6-(1,2,3-triazol-1-yl)purine nucleosides were synthesized.
Bizdēna, Ērika, Novosjolova, Irina, Turks, Māris   +2 more
core  

N‐(1H‐Indazolyl) Aryl Sulfonamide Hybrids as Potential Dihydropteroate Synthase Inhibitors: In Vitro Antibacterial Activity Against Escherichia coli and Staphylococcus aureus and Computational Modeling

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Sixteen indazole–sulfonamide hybrids exhibit species‐dependent antibacterial activity against E. coli and S. aureus, with the lead compound displaying an eightfold lower MIC than sulfathiazole against E. coli. Molecular docking against wild‐type and Sul1‐resistant dihydropteroate synthase identifies a candidate retaining binding affinity toward the ...
Romaisaa Boudza, Ferdaous Elandaloussi, Khalid Boujdi, Jaume Segura‐Garcia, Nabil El Brahmi, Saïd El Kazzouli, Ismaïl Moukadiri, Sergi Maicas, Salim Bounou   +8 more
wiley   +1 more source

Adenylosuccinate lyase in pancreatic ductal adenocarcinoma chemoresistance: from purine metabolism to metabolic vulnerability. [PDF]

Cancer Drug Resist
Hsu TW, Su CM, Su YH, Liao PH, Saengboonmee C, Wang WY, Chen HA.   +6 more
europepmc   +1 more source

Iron(II) and Copper(II) Ions Modulating Binding Interaction of Sugar‐Based Silatrane With DNA: Analytical and Theoretical Validation

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
A new D‐glucamine‐based triazolyl silatrane and its Fe(II)/Cu(II) complexes exhibit metal‐induced modulation of CT‐DNA binding. Experimental and theoretical investigations reveal enhanced binding affinity and conversion from groove binding to a mixed groove‐binding/intercalative interaction. ABSTRACT Research on molecular systems capable of interacting
Gurjaspreet Singh, Pawan, Brij Mohan
wiley   +1 more source

Purinergic and Energy Metabolism Disruption in Oxidative Stress-Mediated Immunotoxicity Induced by Aflatoxin B₁ and Fumonisin B₁. [PDF]

J Fungi (Basel)
Mary VS, Velez PA, Quiroz S, Díaz Iriso SA, Amilibia C, Rubinstein HR, Theumer MG.   +6 more
europepmc   +1 more source