Reactive Oxygen Species in Breast Cancer: From Redox Dysregulation to ROS‐Responsive Therapeutics
ABSTRACT Breast cancer is the most frequently diagnosed malignancy among women worldwide, with 2.3 million new cases and approximately 670,000 deaths reported in 2022 alone. Despite advances in therapy, metastasis and acquired drug resistance remain major clinical challenges.
Marija Nikolovska +5 more
wiley +1 more source
Structural basis for allosteric regulation of mycobacterial guanosine 5´-monophosphate reductase by ATP and GTP. [PDF]
Doležal M +7 more
europepmc +1 more source
Gut Microbiomes of Two Bamboo Locusts Reveal Divergent Metabolic Potentials
We compared the gut microbiota of two bamboo‐feeding locust pests, Ceracris kiangsu and Ceracris nigricornis, using 16S rRNA amplicon sequencing for six geographic populations of C. kiangsu and publicly available C. nigricornis datasets. Both species were dominated by Firmicutes and Proteobacteria, but showed significant differences in community ...
Hong‐Yu Liao +6 more
wiley +1 more source
Regulation of the biosynthesis and interconversion of purine nucleotides [PDF]
openaire +2 more sources
Characterization of histamine H_2-receptors in human neutrophils with a series of guanidine analogues of impromidine: Are cell type-specific H_2-receptors involved in the regulation of NADPH oxidase? [PDF]
Seifert, Roland +2 more
core +1 more source
This study analyzed the chloroplast genomes of 60 Isoetes species to characterize codon usage bias patterns and understand the evolutionary forces shaping this ancient lineage of aquatic vascular plants. The findings reveal a highly conserved chloroplast genome structure with relatively weak codon usage bias, primarily driven by mutation pressure ...
Boxiong Li +8 more
wiley +1 more source
Metabolite glues as a means of purine sensing and chemotherapeutic response. [PDF]
Witus SR +7 more
europepmc +1 more source
Synthetic Food Colorants and Gut Microbiota: A Systematic Review of Preclinical Studies
ABSTRACT Growing evidence suggests that industrial food processing, including the excess consumption of food additives, might have a negative impact on human health. Despite regulatory safety evaluations, their impact on gut microbiota remains poorly characterized.
Sebastiano Alfio Torrisi +9 more
wiley +1 more source
Conformational analysis of nucleic acids for optimizing DNA and RNA topological models. [PDF]
Archambault P +3 more
europepmc +1 more source
This graphical abstract compares four fermentation strategies for D. nobile rice wine: simultaneous inoculation without D. nobile (SW), simultaneous inoculation with D. nobile (DnSW), sequential inoculation without D. nobile (WS), and sequential inoculation with D. nobile (DnWS). Simultaneous inoculation (SW/DnSW) enhanced volatile compound content (up
Hongling Gan +7 more
wiley +1 more source

