Results 211 to 220 of about 78,151 (289)

Implication of xanthine oxidoreductase in oxidative stress-related chronic diseases. [PDF]

Front Endocrinol (Lausanne)
Nelson KL, Voruganti VS.
europepmc   +1 more source

How Plants May Maintain Protein Homeostasis Under Rising Atmospheric CO2

Plant, Cell &Environment, Volume 49, Issue 5, Page 2654-2672, May 2026.
ABSTRACT Vascular plants may employ several physiological mechanisms to stabilize their protein contents as atmospheric CO2 concentrations change over a day, year, decade, or century. One mechanism is that plants may rely more on soil ammonium as their nitrogen source when CO2 increases.
Arnold J. Bloom, Xiaoxiao Shi, Nathan M. Hannon   +2 more
wiley   +1 more source

Integrated analysis of transcriptome and metabolome reveals the molecular interactions and regulation of muscle flavor precursors in Tengchong Snow chickens and AA broilers. [PDF]

Front Vet Sci
Yang M, Zhang R, Zhao J, Jian Z, Wu H, Zi X, Wang K, Xu Z, Ge C, Jia J, Liu L, Dou T.   +11 more
europepmc   +1 more source

Structural and molecular basis for allosteric regulation and catalytic coupling of human phosphoribosylformylglycinamidine synthase. [PDF]

Nat Commun
Sharma N, Zhou W, French JB.
europepmc   +1 more source

Correction: Combined deletion of cytosolic 5'-nucleotidases IA and II lowers glycemia by improving skeletal muscle insulin action and lowering hepatic glucose production. [PDF]

J Biol Chem
Jacobs R, Herinckx G, Galland N, Balty C, Vertommen D, Rider MH, Johanns M.   +6 more
europepmc   +1 more source

Fluorine‐18‐Labeled Nucleotide Analogs Targeting Ecto‐5'‐Nucleotidase (CD73) for Positron Emission Tomography Imaging of Solid Tumors

Angewandte Chemie, Volume 138, Issue 17, 20 April 2026.
Fluorine‐18‐labeled CD73 inhibitor [18F]PSB‐19427 enables noninvasive PET mapping of CD73 overexpression in triple‐negative breast (TNBC) and pancreatic cancer. For [18F]PSB‐19427, specific binding in human tumor tissues, favorable biodistribution with prolonged blood retention, robust tumor uptake, and superiority to [18F]FDG in a TNBC model ...
Clemens Dobelmann, Constanze C. Schmies, Georg Wilhelm Rolshoven, Mirko Scortichini, Stefan Wagner, Andreas Isaak, Riham M. Idris, Jennifer Dabel, Lucie Grey, Karolina Losenkova, Susanne Moschütz, Haneen Al Hroub, Antje Keim, Sandra Höppner, Jouko Sandholm, Pia Boström, Maija Hollmén, Norbert Sträter, Sven Hermann, Gennady G. Yegutkin, Kenneth A. Jacobson, Sonja Schelhaas, Christa E. Müller, Anna Junker   +23 more
wiley   +2 more sources

Mechanism of Sodium-Glucose Cotransporter-2 Inhibitors for Uricosuria. [PDF]

Electrolyte Blood Press
Bae E.
europepmc   +1 more source

The Role of Chemistry Across Disciplines From Humanities to Life Sciences in Understanding Complexity and Emergence

Angewandte Chemie, Volume 138, Issue 17, 20 April 2026.
This study explores the origins of life by linking prebiotic chemistry, the emergence of information‐carrying molecules such as RNA and proteins, and philosophical questions about consciousness. The study emphasizes the role of molecular evolution in the Central Dogma and provides insights into the chemical origins of biology and the basis of life's ...
Harald Schwalbe, Josef Wachtveitl, Alexander Heckel, Florian Buhr, Sabrina Toews, Thomas M. Schimmer   +5 more
wiley   +2 more sources

Impact of 2'-deoxyribo-purine substrates on nonenzymatic RNA template-directed primer extension. [PDF]

Nucleic Acids Res
Fang Z, Acikgoz O, Jia X, Essex J, Wen R, Szostak JW.   +5 more
europepmc   +1 more source

One‐Step and Universal Strategy for the Synthesis of Hypermodified Uracil Phosphoramidites acp3U and cmnm5U

Chemistry – A European Journal, Volume 32, Issue 16, 25 April 2026.
One‐step, highly efficient, and scalable synthesis of acp3U phosphoramidite is described, as well as a new alternative synthesis of cmnm5U phosphoramidite from a highly versatile intermediate. Latter could be scaled‐up, split, and aliquots turned simultaneously into cmnm5U, nm5U, and mnm5U.
Ewa Mejdr, Lena Heinickel, Thomas Carell, Ivana Mejdr   +3 more
wiley   +1 more source