Results 211 to 220 of about 144,015 (298)

Molecular Omics Unveils the Antimicrobial Mechanism of UV-LED-Induced Chitosan Composite Film Against Penicillium italicum. [PDF]

J Food Sci
Xing Y, Lei C, Fan X, Xu Q, Luoguo W, Tian Y, Zhou X, He L, Yang L.   +8 more
europepmc   +1 more source

Amino Acid Metabolism in Health and Disease

MedComm, Volume 7, Issue 9, September 2026.
This graphical abstract delineates the multifaceted role of amino acid metabolism in health and disease. It illustrates how amino acids sustain physiological homeostasis across the liver, kidney, brain, heart, intestine, muscle, skeleton, and immune system.
Zhiwei Su, Jinyu Liu, Xiaoliang Deng, Yanqun Luo, Haiping Xue, Lei Wang, Lianjun Xing, Tao Wu   +7 more
wiley   +1 more source

Ultra-high-performance liquid chromatography high-resolution mass spectrometry-based screening of purine and pyrimidine metabolites in cow milk collected across 4 different seasons. [PDF]

JDS Commun
Errico M, Rocchetti G, Lapris M, Novara V, Bellassi P, Fumagalli F, Boldini A, Stroppa A, Gallo A.   +8 more
europepmc   +1 more source

RNA‐Binding Proteins: Function, Biological Mechanisms, and Therapeutic Opportunities

MedComm, Volume 7, Issue 9, September 2026.
RNA‐binding proteins (RBPs) regulate RNA stability, localization, translation, and splicing through intrinsic binding domains and interactions with diverse cellular partners. Their competitive and cooperative networks shape disease‐related RNA programs, especially in cancer.
Ling Li, Xiuli Yan, Qing Ji, Hui Zhang
wiley   +1 more source

Artemisia argyi-enriched fermented soybean meal alleviates ETEC K88-induced intestinal injury in mice in association with gut microbiota remodeling and purine metabolic alterations. [PDF]

BMC Vet Res
Wang W, Wang H, Sun C, Chen Q, Zhang Y, Miao C, Zhu S, Xiong W.   +7 more
europepmc   +1 more source

High‐Content CRISPR Screening: Methods and Applications

MedComm, Volume 7, Issue 9, September 2026.
High‐content CRISPR screening represents a paradigm shift in functional genomics, moving beyond traditional survival‐based readouts to enable multidimensional mapping of genotype–phenotype relationships. This review systematically outlines the methodological evolution of this approach, detailing advances in perturbation modalities, delivery systems ...
Yike Zhang, Yimeng Zhang, Xudong Tang, Xinyu Deng, Yitian Zhou, Yanfeng Wu, Jianhua Luo   +6 more
wiley   +1 more source

Itaconic Acid Directly Binds to the Cysteine Residue of PurF: A Novel Mechanism for Inhibiting Purine Metabolism in Porcine Pathogenic <i>Escherichia coli</i>. [PDF]

Microorganisms
Liu H, Li X, Zhang X, Ge Y, Chen Y, Li X, Wu Z.   +6 more
europepmc   +1 more source

Heat Shock Proteins in Cancer: Mechanisms and Therapeutic Targeting

MedComm, Volume 7, Issue 9, September 2026.
This review illustrates heat shock proteins (HSPs) as central regulators of cancer metabolic reprogramming. By stabilizing key metabolic enzymes and coordinating glycolysis, oxidative phosphorylation, redox homeostasis, and stress adaptation, HSPs support tumor growth, metastasis, and therapeutic resistance. Targeting HSP networks may therefore provide
Sheng Ma, Chen‐Qian Liu, Si‐Yang Ma, Shao‐Gang Wang, Qi‐Dong Xia, Meng‐Yao Xu   +5 more
wiley   +1 more source

Metabolomic Analysis of Lytic KSHV Infection: Induced Host Nucleotide Metabolism Is Required for Infectious Virus Production. [PDF]

Viruses
Hisam F, Winn EA, Mukherjee S, Price SE, Gaspar YA, Wang C, Baniasadi HR, Delgado T, Sanchez EL.   +8 more
europepmc   +1 more source

Nitric Oxide in Cancer: Mechanisms, Dual Role, and Therapeutic Strategies

MedComm – Oncology, Volume 5, Issue 3, September 2026.
Nitric oxide exerts concentration‐dependent dual roles in cancer, functioning as either a tumor promoter or suppressor. This review comprehensively examines NO's multifaceted regulation of tumor biology, including S‐nitrosylation signaling, metabolic reprogramming, immunemodulation, and therapy resistance, and highlights emerging therapeutic strategies
Jia Shao, Honghua Zhang, Jingyu Chen, Ziyu Qian, Ning Zhang, Yihua Zhang, Hui Ye, Jianbing Wu, Zhangjian Huang   +8 more
wiley   +1 more source