SPROUTS_DB: An Implemented Database of Contaminants for Extracellular Vesicle Proteomics Studies
ABSTRACT Current proteomics techniques allow rapid identification and quantification of proteins within any given biological source. However, LC–MS/MS proteomics is vulnerable to laboratory and sample‐associated contaminants. Therefore, accurate identification and annotation of such contaminants is crucial for development of reliable databases ...
Maria Gaetana Giovanna Pittalà +10 more
wiley +1 more source
Simultaneous spectrofluorimetric determination of nasal cyclic nucleotides as biochemical markers in post-COVID-19 olfactory dysfunction using supramolecular-enhanced derivative spectroscopy. [PDF]
Alsobky ME +3 more
europepmc +1 more source
Metabolic Markers as Potential Risk Factors in Pulmonary Hypertension
ABSTRACT Pulmonary hypertension (PH) is a condition characterized by elevated mean pulmonary arterial pressure confirmed by right heart catheterization. PH involves both structural and functional changes in the pulmonary vascular bed. Since 2022, a four‐level risk stratification has been used to predict 1‐year mortality at follow‐up.
Sarah McGarrity +2 more
wiley +1 more source
This study presents a plasmonic thermal lateral flow (ThermoLFA) biosensor for ultrasensitive, early detection of biomolecules. By combining plasmonic gold nanoprisms (AuNPrs) and near‐infrared (NIR) laser activation, it enhances signal output beyond conventional LFAs.
Carlos Cuestas Ayllón +5 more
wiley +1 more source
Integrated transcriptomic and metabolomic analysis identifies C5NT1AL as a candidate gene influencing inosine monophosphate levels in chicken breast muscle. [PDF]
Yang H +7 more
europepmc +1 more source
Oligonucleotides form spontaneously through hot wet‐dry cycling of pure non‐activated nucleotides. No catalytic agents were added, and pH was naturally buffered by the nucleotides. Oligonucleotide formation was confirmed and quantified using mass spectrometry, spectroscopy and electrophoresis, establishing a solid baseline for the intrinsic extent of ...
Simon H. J. Eiby +5 more
wiley +1 more source
Mycophenolate mofetil reduces the branching of microglial processes. [PDF]
Teruya RI +6 more
europepmc +1 more source
Reactive Oxygen Species‐Induced Damage in Cryopreserved Bovine Sperm: Mitigation Strategies
Cryopreservation of bovine sperm results in overproduction of ROS due to osmotic pressure variations, ice crystals and dysfunction of mitochondria, which causes lipid peroxidation, fragmentation of DNA, protein damage and ultimately decline of post‐thaw sperm quality.
Mst. Mahomudha Akhtar +4 more
wiley +1 more source
Research progress on the correlation between gut microbiota and the occurrence of hyperuricemia. [PDF]
Wang Q +5 more
europepmc +1 more source
Gut Metabolism Links Precision Nutrition, Exercise, and Healthspan in Drosophila melanogaster
This study reveals that precision nutrition, exercise, and gut microbiota pathways synergistically regulate host metabolism, redox balance, and arginine‐spermidine metabolism, enhancing antioxidant defenses and mitochondrial stabilization to combat aging.
Fangchao Wei +6 more
wiley +1 more source

