Results 231 to 240 of about 78,151 (289)

Purine nucleotide catabolism in placenta

American Journal of Obstetrics and Gynecology, 1964
Abstract Soluble extracts were utilized to delineate the catabolic pathways of purine 2′,3′- and 5′-ribonucleoside monophosphates in human placenta and to measure the relative activities of the enzymes involved. Derivatives of adenine and hypoxanthine are converted to hypoxanthine, and derivatives of guanine are converted to xanthine.
T T, HAYASHI, R C, BALDRIDGE, P S, OLMSTED, D L, KIMMEL   +3 more
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Alterations in purine nucleotide pyrophosphorylases and resistance to purine analogues

Biochimica et Biophysica Acta, 1961
Abstract Resistance to purine analogues in mutants isolated from Salmonella typhimurium , strain LT-2 , resulted in the loss of specific purine nucleotide pyrophosphorylases. Thus, mutants resistant to 2,6-diaminopurine, 6-mercaptopurine, and 8-azaguanine lacked adenylic, inosinic and guanylic pyrophosphorylases, respectively. The mutants resistant
G P, KALLE, J S, GOTS
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Thermodynamics of the purine nucleotide cycle

Biophysical Chemistry, 2006
Since the standard Gibbs energies of formation are known for all the species in the purine nucleotide cycle at 298.15 K, the functions of pH and ionic strength that yield the standard transformed Gibbs energies of formation of the ten reactants can be calculated.
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Purine Nucleotide Catabolism in Rat Liver

2006
The higher specific radioactivity of ALL in comparison to UA, which are observed after administration of labelled precursors, changed when, oxonic acid and allopurinol, inhibitors of UA and ALL formation were administrated. To interpret these results, it is worth while to recall that nucleotide metabolism can be represented as a complex sequence ...
Marinello E., Pagani R., Arezzini L., Porcelli B., Cinci G., Terzuoli L.   +5 more
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Disturbances of purine nucleotide metabolism in uremia

Seminars in Nephrology, 2004
The increased concentration of adenosine triphosphate (ATP) in erythrocytes from patients with chronic renal failure (CRF) has been observed in many studies but the mechanism leading to these abnormalities still is controversial. It is believed that hyperphosphatemia and metabolic acidosis triggering enhanced reutilization of purine bases are the ...
Bolesław, Rutkowski, Julian, Swierczynski, Ewa, Slominska, Marek, Szolkiewicz, Ryszard T, Smolenski, Maciej, Marlewski, Barbara, Butto, Przemysław, Rutkowski   +7 more
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Purine nucleotide cyclases in the malaria parasite

Trends in Parasitology, 2004
Cells use a variety of signal transduction pathways to coordinate their responses to changes in both the extracellular and intracellular environment. Activation of these pathways is often receptor mediated, resulting in the synthesis of second messenger molecules such as cAMP and cGMP.
David A, Baker, John M, Kelly
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3 Purine, Purine Nucleoside, and Purine Nucleotide Aminohydrolases

1971
Publisher Summary This chapter discusses the chemical significance of adenosine aminohydrolase, 5′-adenylic acid aminohydrolase, adenine nucleoside, nucleotide aminohydrolase, guanine aminohydrolase, and guanosine aminohydrolase. The partially purified adenine aminohydrolase from Azotobacter vinelandii catalyzes the anaerobic conversion of adenine ...
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Purine nucleotide biosynthesis in gastrointestinal mucosa

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1973
Abstract Two methods were used to elucidate the relative dependence of intestinal mucosa on the alternative pathways of purine nucleotide biosynthesis. While salvage activity was high, there was no evidence of active de novo purine synthesis by either method, suggesting that intestinal mucosa is dependent on salvage pathway activity for the provision
A M, Mackinnon, D J, Deller
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Studies of the Regulation of Purine Nucleotide Catabolism

Canadian Journal of Biochemistry, 1975
Ehrlich ascites tumor cells containing radioactive ATP were incubated in vitro with a range of concentrations of 2-deoxyglucose in order to produce different rates of ATP catabolism. Concentrations of all radioactive products of ATP catabolism were measured, and apparent rates of adenylate deaminase and inosinate dehydrogenase and of adenylate and ...
C A, Lomax, A S, Bagnara, J F, Henderson
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