Results 71 to 80 of about 7,481 (163)

Role and Mechanism of Microglia in White Matter Injury Recovery in Ischemic Stroke

Immunity, Inflammation and Disease, Volume 13, Issue 8, August 2025.
Many studies have shown that stroke can cause microglia activation, and activated microglia differentiate into different types according to different time and region, and different types of microglia play an important role in the process of white matter recovery.
Yi‐Sha Guo, Yunlin Shang, Jiajia Yao, Xia Bi   +3 more
wiley   +1 more source

Molecular Mechanisms of Chronic Pain and Therapeutic Interventions

MedComm, Volume 6, Issue 8, August 2025.
We offer a comprehensive overview of the distinctive molecular mechanisms underlying nociceptive, neuropathic, and nociplastic pain, including the immune responses, ion channels, monoaminergic imbalance, and neuroinflammation. Subsequently, we summarized the status quo of nociceptive, neuropathic, and nociplastic pain managementmanipulation.
Zhen Li, Xing Li, Jieqiong Liu, Rao Sun, Yingze Ye, Hongbing Xiang, Fang Luo, Shiyong Li, Ailin Luo   +8 more
wiley   +1 more source

Functional characterization of P2Y1 and P2X4 receptors in human neuroblastoma SK-N-MC cells [PDF]

, 2015
Nucleotides are important signalling molecules in both the peripheral and central nervous system. However, the in vitro study of their receptors can be hampered by the heterogeneity of primary neuronal cultures. The use of clonal neuroblastoma cell lines
Bullido, María Jesús, Gualix, Javier, León-Otegui, Miriam, Miras-Portugal, M. Teresa, Recuero, Maria, Valdivieso, Fernando   +5 more
core   +1 more source

Functional maturation of isolated neural progenitor cells from the adult rat hippocampus [PDF]

, 2004
Although neural progenitor cells (NPCs) may provide a source of new neurons to alleviate neural trauma, little is known about their electrical properties as they differentiate.
Chipperfield H., Gage F.H., Gage F.H., Grynkiewicz G., Hamill O.P., Hogg R.C., Koshimizu T.A., Nurcombe V., Palmer T.D., Piper D.R., Reynolds B.A., Richards L.J., Song H.J., Standen N.B., Thompson S.M., Virginio C.   +15 more
core   +1 more source

Arabidopsis thaliana Cyclic Nucleotide‐Gated Channel 19 is involved in root extracellular ATP and Pep1 signalling

New Phytologist, Volume 248, Issue 5, Page 2192-2197, December 2025.
Youzheng Ning, Bryony C. I. C. Jacobs, Clementine Langlet, Limin Wang, Zhizhong Song, Adeeba M. Dark, Elsa Matthus, Sebastian Eves‐van den Akker, Taufiq Rahman, Julia M. Davies   +9 more
wiley   +1 more source

Pre- and postsynaptic actions of ATP on neurotransmission in rat submandibular ganglia [PDF]

, 2001
The pre- and postsynaptic actions of exogenously applied ATP were investigated in intact and dissociated parasympathetic neurotics of rat submandibular ganglia.
A.B Smith, Armour, Bo, Boehm, D.-M Liu, D.J Adams, Dutton, Edwards, Evans, Fieber, Galligan, Hamill, Hansen, Hansen, Hansen, Hansen, Inokuchi, Kawa, Khakh, Le, Li, Liu, Liu, Luetje, M.A Hansen, Nabekura, Navone, Ralevic, Seabrook, Silinsky, Smith, Smith, Sperlagh, Sun, Tenneti, von Kugelgen, Worthington, Yunaev, Zhou, Zhou   +39 more
core   +1 more source

P2Y2 and P2Y6 receptor activation elicits intracellular calcium responses in human adipose-derived mesenchymal stromal cells [PDF]

, 2018
Adipose tissue contains self-renewing multipotent cells termed mesenchymal stromal cells. In situ, these cells serve to expand adipose tissue by adipogenesis, but their multipotency has gained interest for use in tissue regeneration.
A Nardi-Schreiber, A Nishimura, A Surprenant, C Kaebisch, C Kennedy, CE Parr, CH Jo, CL Herold, D Communi, D Ecke, D Ferrari, DW Nelson, E Kerkelä, F Ashour, F Saldanha-Araujo, FMP Tonelli, G Burnstock, GE Torres, GG Yegutkin, GG Yegutkin, HJ Kim, HS Kim, J Gimble, J Lessard, JB Noronha-Matos, Jeremy Turner, JH Houtgraaf, JK Chambers, JM Boeynaems, K Hoffmann, KA Jacobson, KL Spalding, KS Lee, L Stokes, L-H Jiang, L-H Jiang, LK Mamedova, M Ciciarello, M Dominici, M Liu, M Omatsu-Kanbe, M Rafehi, N D’Ambrosi, N Zippel, RJ Evans, S Damer, S Govindan, S Hagmann, S Kotnis, S Madec, S Meis, S Satrawaha, Samuel J. Fountain, Seema Ali, SJ Ormond, T Fink, T Thesleff, V Hernandez-Olmos, V Turinetto, W Li, W Liang, X Dong, Y-C Kim   +62 more
core   +1 more source

P2X7 receptor in epilepsy; role in pathophysiology and potential targeting for seizure control. [PDF]

, 2012
The P2X7 receptor is an ATP-gated non-selective cation-permeable ionotropic receptor selectively expressed in neurons and glia in the brain. Activation of the P2X7 receptor has been found to modulate neuronal excitability in the hippocampus and it has ...
Diaz-Hernandez, Miguel, Engel, Tobias, Henshall, David C, Jimenez-Pacheco, Alba, Miras-Portugal, Maria Teresa   +4 more
core   +2 more sources

Release of ATP in the ventral medulla during hypoxia in rats: role in hypoxic ventilatory response [PDF]

, 2005
P2X2 receptor subunits of the ATP-gated ion channels are expressed by physiologically identified respiratory neurons in the ventral respiratory column, implicating ATP in the control of respiratory activity.
Dale, Nicholas, Gourine, Alexander V., Llaudet, Enrique, Spyer, K. Michael   +3 more
core   +2 more sources

The platelet ATP and ADP receptors. [PDF]

, 2006
peer reviewedThis review focuses on recent findings on the physiology of these platelet ADP and ATP receptors, their distinct downstream intracellular signaling pathways as well as on the available agonists, antagonists and inhibitors that allow their ...
Hoylaerts, Marc F, Oury, Cécile, Toth-Zsamboki, Emese, Vermylen, Jos   +3 more
core   +1 more source