Results 111 to 120 of about 39,382 (265)
ADP receptor P2Y(13) induce apoptosis in pancreatic beta-cells.
, 2010 Pancreatic beta-cell loss represents a key factor in the pathogenesis of diabetes. Since the influence of purinergic signaling in beta-cell apoptosis has not been much investigated, we examined the role of the ADP receptor P2Y(13) using the pancreatic ...
Erlinge, David, +9 more
core +1 more source
The Role of Neuropeptide Y in Dental Pulp: Balancing Neurogenic Inflammation and Pain Modulation
International Endodontic Journal, EarlyView.ABSTRACT Background Dental pulp is a densely innervated, low‐compliance tissue in which neurogenic inflammation can rapidly escalate into oedema, raised intrapulpal pressure, microvascular compromise, and pain. While Substance P (SP) and Calcitonin gene‐related peptide (CGRP) are well‐established drivers of pulp vasodilation, the Neuroopeptide Y (NPY ...
Javier Caviedes‐Bucheli +3 more
wiley +1 more source
Postnatal developmental changes in the laryngeal chemosensory cell clusters of rats
Journal of Anatomy, EarlyView.Chemosensory cell clusters appeared in the rat larynx 2 days after birth and were already connected to afferent nerve fibers. Their number increased until 3 weeks of age, then stabilized while continuing to grow through the addition of new cells. Because their number reached a plateau around the time of weaning, their development may be linked to ...
Sayed Sharif Abdali +5 more
wiley +1 more source
The P2X7 Receptor in Inflammatory Diseases: Angel or Demon?
Frontiers in Pharmacology, 2018 Under physiological conditions, adenosine triphosphate (ATP) is present at low levels in the extracellular milieu, being massively released by stressed or dying cells.
Luiz E. B. Savio +3 more
doaj +1 more source
Peri‐Implantitis and Periodontitis: Biological Convergence, Contextual Divergence
Journal of Periodontal Research, EarlyView.Periodontal and peri‐implant tissues differ and coincide in many aspects, from the clinical and radiological perspective, including histology, microbiology, and molecular markers. Thus, health and disease may also follow different and similar routes.
Pablo Galindo‐Moreno +6 more
wiley +1 more source
NPY mediates ATP-induced neuroproliferation in adult mouse olfactory epithelium
Neurobiology of Disease, 2010 In the CNS, ATP is released upon injury and promotes neuroproliferation via purinergic receptors. In the olfactory epithelium, ATP promotes the synthesis and release of neurotrophic factor NPY in neonates and induces neuroproliferation in neonatal and ...
Cuihong Jia, Colleen Cosgrove Hegg
doaj +1 more source
Optimization of photobiomodulation therapy for spinal cord injury: A review
Photochemistry and Photobiology, EarlyView.Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew +3 more
wiley +1 more source
P2X7 Receptor: Warburg effect revisited
, 2012 Ability to adapt to conditions of limited nutrient supply is a key feature of all cells. This may require a complex re-organization of metabolic pathways to balance energy generation and production of biosynthetic intermediates.
Amoroso, Francesca Saveria
core
Purinergic Receptors in Dendritic Cells
Journal of Inflammation ResearchDendritic cells (DCs) are regarded as highly effective antigen-presenting cells (APCs) and play a crucial role in immunomodulation. A growing body of research focuses on extracellular purines and their purinergic receptors in DCs. In this review, we provide an overview of the expression and function of purinergic receptors (P1 and P2) in DCs.
Miaomiao Wang +4 more
openaire +3 more sources