Results 171 to 180 of about 2,316,796 (350)

Investigation of the Pathomechanism of Chronic Cough Using an In Vitro Approach

open access: yes
Clinical &Experimental Allergy, Volume 55, Issue 3, Page 247-249, March 2025.
Umesh Singh, Jonathan A. Bernstein
wiley   +1 more source

The Aquaporin‐4 Expression and Localization in the Olfactory Epithelium Modulate the Odorant‐Evoked Responses and Olfactory‐Driven Behavior

open access: yesGlia, Volume 73, Issue 8, Page 1642-1659, August 2025.
Main Points AQP4ex and OAP‐forming AQP4M23 are expressed in non‐neuronal cells of the olfactory epithelium. AQP4ex‐KO and OAP‐null mice show reduced cell density, including OSNs, and impaired odor responses and behavior, with AQP4ex emerging as key regulator.
Donatella Lobraico   +8 more
wiley   +1 more source

Role of P2-purinergic receptors in rat Leydig cell steroidogenesis [PDF]

open access: green, 1996
C. Foresta   +5 more
openalex   +1 more source

Astroglial CB1 Reveal Sex‐Specific Synaptic Effects of Amphetamine

open access: yesGlia, Volume 73, Issue 8, Page 1673-1691, August 2025.
Main Points Astroglial CB1 mediate long‐term depression in the NAc through purine release. Amphetamine occludes LTD in male mice by inducing the saturation of A1 receptors. Astroglial CB1 mediate behavioral amphetamine effects in males, but not in females.
Yamuna Mariani   +15 more
wiley   +1 more source

New paradigms in purinergic receptor ligand discovery. [PDF]

open access: yesNeuropharmacology, 2023
Jacobson KA   +3 more
europepmc   +1 more source

Revolutionizing Autoimmune Research: The Role of Caveolin‐1

open access: yesImmunity, Inflammation and Disease, Volume 13, Issue 8, August 2025.
ABSTRACT Introduction Caveolins (Cav) include Cav‐1, Cav‐2, and Cav‐3, with Cav‐1 being the most studied due to its prominent role as a major component of plasma membrane caveolae. Cav‐1 is involved in a wide range of cellular functions and plays a key role in regulating signaling pathways related to immune responses and inflammation.
Yanan Gao   +8 more
wiley   +1 more source

The naked mole-rat has a functional purinergic pain pathway despite having a non-functional peptidergic pain pathway

open access: yesNeurobiology of Pain, 2020
Naked mole-rats (Heterocephalus glaber) have adaptations within their pain pathway that are beneficial to survival in large colonies within poorly ventilated burrow systems, with lower O2 and higher CO2 ambient levels than ground-level environments ...
Brigitte M. Browe   +5 more
doaj  

Molecular Mechanisms of Chronic Pain and Therapeutic Interventions

open access: yesMedComm, Volume 6, Issue 8, August 2025.
We offer a comprehensive overview of the distinctive molecular mechanisms underlying nociceptive, neuropathic, and nociplastic pain, including the immune responses, ion channels, monoaminergic imbalance, and neuroinflammation. Subsequently, we summarized the status quo of nociceptive, neuropathic, and nociplastic pain managementmanipulation.
Zhen Li   +8 more
wiley   +1 more source

ROLE OF PURINERGIC RECEPTORS IN IMMUNE RESPONSE

open access: yesJournal of microbiology, epidemiology and immunobiology, 2016
Purine receptors are located on immune and somatic cells of animal and human organisms. Summation of signals from purine and TOLL-like receptors takes place on the level of inflammasome formation and results in summation of the first and second signals of innate immunity.
openaire   +5 more sources

Glioblastoma Tumor Microenvironment and Purinergic Signaling: Implications for Novel Therapies

open access: yesPharmaceuticals
Glial-origin brain tumors, particularly glioblastomas (GBMs), are known for their devastating prognosis and are characterized by rapid progression and fatal outcomes.
Martina Bedeschi   +3 more
doaj   +1 more source

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