Results 171 to 180 of about 2,316,796 (350)
Investigation of the Pathomechanism of Chronic Cough Using an In Vitro Approach
Clinical &Experimental Allergy, Volume 55, Issue 3, Page 247-249, March 2025.
Umesh Singh, Jonathan A. Bernstein
wiley +1 more source
Main Points AQP4ex and OAP‐forming AQP4M23 are expressed in non‐neuronal cells of the olfactory epithelium. AQP4ex‐KO and OAP‐null mice show reduced cell density, including OSNs, and impaired odor responses and behavior, with AQP4ex emerging as key regulator.
Donatella Lobraico+8 more
wiley +1 more source
Role of P2-purinergic receptors in rat Leydig cell steroidogenesis [PDF]
C. Foresta+5 more
openalex +1 more source
Astroglial CB1 Reveal Sex‐Specific Synaptic Effects of Amphetamine
Main Points Astroglial CB1 mediate long‐term depression in the NAc through purine release. Amphetamine occludes LTD in male mice by inducing the saturation of A1 receptors. Astroglial CB1 mediate behavioral amphetamine effects in males, but not in females.
Yamuna Mariani+15 more
wiley +1 more source
New paradigms in purinergic receptor ligand discovery. [PDF]
Jacobson KA+3 more
europepmc +1 more source
Revolutionizing Autoimmune Research: The Role of Caveolin‐1
ABSTRACT Introduction Caveolins (Cav) include Cav‐1, Cav‐2, and Cav‐3, with Cav‐1 being the most studied due to its prominent role as a major component of plasma membrane caveolae. Cav‐1 is involved in a wide range of cellular functions and plays a key role in regulating signaling pathways related to immune responses and inflammation.
Yanan Gao+8 more
wiley +1 more source
Naked mole-rats (Heterocephalus glaber) have adaptations within their pain pathway that are beneficial to survival in large colonies within poorly ventilated burrow systems, with lower O2 and higher CO2 ambient levels than ground-level environments ...
Brigitte M. Browe+5 more
doaj
Molecular Mechanisms of Chronic Pain and Therapeutic Interventions
We offer a comprehensive overview of the distinctive molecular mechanisms underlying nociceptive, neuropathic, and nociplastic pain, including the immune responses, ion channels, monoaminergic imbalance, and neuroinflammation. Subsequently, we summarized the status quo of nociceptive, neuropathic, and nociplastic pain managementmanipulation.
Zhen Li+8 more
wiley +1 more source
ROLE OF PURINERGIC RECEPTORS IN IMMUNE RESPONSE
Purine receptors are located on immune and somatic cells of animal and human organisms. Summation of signals from purine and TOLL-like receptors takes place on the level of inflammasome formation and results in summation of the first and second signals of innate immunity.
openaire +5 more sources
Glioblastoma Tumor Microenvironment and Purinergic Signaling: Implications for Novel Therapies
Glial-origin brain tumors, particularly glioblastomas (GBMs), are known for their devastating prognosis and are characterized by rapid progression and fatal outcomes.
Martina Bedeschi+3 more
doaj +1 more source