Results 161 to 170 of about 39,382 (265)

Cdk5 modulates orofacial pain through P2X2/3 purinergic receptor-mediated signaling in trigeminal neurons. [PDF]

Front Pharmacol
Sandoval R, Pinto-Pardo N, Duran C, Castro P, Rossi G, González-Billault C, Pertusa M, Madrid R, Coddou C, Utreras E.   +9 more
europepmc   +1 more source

Blocking P2Y2 purinergic receptor prevents the development of lipopolysaccharide-induced acute respiratory distress syndrome. [PDF]

Front Immunol, 2023
Kargarpour Z, Cicko S, Köhler TC, Zech A, Stoshikj S, Bal C, Renner A, Idzko M, El-Gazzar A.   +8 more
europepmc   +1 more source

The Antipsychotic Aripiprazole Induces Cytotoxicity in Bladder Cancer Cells While Preserving Urothelial and Bladder Function

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
Current bladder cancer therapies can cause toxicity and bladder dysfunction. Brief intravesical‐like aripiprazole exposure reduced bladder cancer cell viability and was associated with redox stress and caspase‐3 activation, while ex vivo findings suggested preserved bladder structure and function, warranting further investigation as a potential ...
Liam A. O'Callaghan, Katie Powell, Russ Chess‐Williams, Catherine McDermott   +3 more
wiley   +1 more source

Non-cell autonomous downregulation of the purinergic receptor P2Y1R promotes neuroprotection after ischemic injury. [PDF]

Front Cell Neurosci
Spagnuolo G, Iacovitti L.
europepmc   +1 more source

Sex-specific effect of P2Y₂ purinergic receptor on glucose metabolism during acute inflammation. [PDF]

Front Endocrinol (Lausanne), 2023
Ulbricht RJ, Rivas CA, Marino H, Snyder E, James D, Makhloufi J, Johnson N, Zimmerman S, Wang J.   +8 more
europepmc   +1 more source

The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 12, Issue 3, Page 362-373, June 2026.
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li, Yue Li, Yan‐Jie Jiang, Ge‐Hua Zhang, Li‐Hong Chang   +4 more
wiley   +1 more source

Integrins α3 and α6 promote Th17 cell migration by activating the purinergic receptor P2X4. [PDF]

Purinergic Signal
Hamoudi C, Lashgari A, Aoudjit F.
europepmc   +1 more source

Purinergic receptor: a crucial regulator of adipose tissue functions. [PDF]

Purinergic Signal, 2023
Wang D, Zhou J.
europepmc   +1 more source

Calcium Buffering in Astrocytes and Its Relevance for Experimental Data Interpretation and Computational Modeling

Journal of Neurochemistry, Volume 170, Issue 6, June 2026.
Components and properties of Ca2+ buffers in astrocytes, which should be considered for data interpretation and in computational modeling of astrocyte Ca2+ activity. ABSTRACT Astrocytic Ca2+ signaling is essential for maintaining physiological brain function, including the modulation of synaptic transmission, neurovascular coupling, and ion homeostasis.
Kerstin Lenk, Andre Zeug, Franziska E. Müller   +2 more
wiley   +1 more source

Damage-induced pyroptosis drives endogenous thymic regeneration by activating the purinergic receptor P2Y2. [PDF]

Cell Death Dis
Kinsella S, Evandy CA, Cooper K, Kirsche E, Warren M, deRoos P, Cardinale A, Iovino L, Granadier D, Smith CW, Hopwo K, Sullivan LB, Velardi E, Dudakov JA.   +13 more
europepmc   +1 more source