Results 171 to 180 of about 39,382 (265)

Altered purinergic receptor expression in the frontal cortex in schizophrenia. [PDF]

open access: yesSchizophrenia (Heidelb), 2022
Alnafisah R   +7 more
europepmc   +1 more source

Asymptomatic Versus Symptomatic Alzheimer's Disease Neuropathology: A Systematic Review of Differences Reported in Post‐Mortem Studies

open access: yesNeuropathology and Applied Neurobiology, Volume 52, Issue 3, June 2026.
Graphical summary of post‐mortem brain tissue findings that differ between symptomatic and asymptomatic AD. Current evidence suggests reduced accumulation of Aβ and p‐tau oligomers, particularly at synapses, preserved neuronal and synaptic integrity and metabolic activity and a dynamic profile of glial and immune responses in ASYMAD.
Thiago Guilherme Rêgo Barros   +6 more
wiley   +1 more source

Early Regional Microglial Remodelling in the Hippocampus of the AppNL‐G‐F Alzheimer's Model

open access: yesNeuropathology and Applied Neurobiology, Volume 52, Issue 3, June 2026.
Microglia undergo profound structural and functional changes during Alzheimer's disease, yet the earliest stages of morphological remodelling that occur prior to amyloid deposition remain poorly defined. Through high‐resolution 3D morphometry in the CA1 region of the hippocampus of AppNL‐G‐F mice, it was found that although microglial numbers and ...
Ryan J. Bevan   +4 more
wiley   +1 more source

Purinergic Receptor Nanoimmunoamplifiers Potentiate Chemoimmunotherapy Efficacy in Hepatocellular Carcinoma. [PDF]

open access: yesBiomater Res
Zhang J   +11 more
europepmc   +1 more source

Acute Sleep Deprivation Shifts Substrate Utilization Toward Greater Fat Oxidation During Incremental Exercise in Recreationally Trained Adults

open access: yesScandinavian Journal of Medicine &Science in Sports, Volume 36, Issue 6, June 2026.
ABSTRACT Sleep deprivation alters metabolic homeostasis and substrate metabolism, but its effect on fat and carbohydrate utilization during exercise is unclear. This study examined the effects of one night of total and partial sleep deprivation on substrate utilization during a maximal fat oxidation test (MFO) in recreationally trained adults.
Marta del Val‐Manzano   +5 more
wiley   +1 more source

P2 purinergic receptor dysregulation in urologic disease. [PDF]

open access: yesPurinergic Signal, 2022
Maynard JP, Sfanos KS.
europepmc   +1 more source

HIF‐Regulated Pannexin‐1 Channel Drives Luminal ATP Accumulation in Kidney Cysts

open access: yesThe FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Autosomal dominant polycystic kidney disease causes progressive cyst enlargement in the kidneys, leading to hypoxia and induction of HIF‐1α. Our study identifies HIF‐1α‐dependent transcriptional upregulation of Pannexin1 (PANX1) in the apical membrane of cyst epithelial cells, promoting ATP release into the cyst lumen.
Kathrin Skoczynski   +10 more
wiley   +1 more source

eATP sensing by the purinergic receptor PA2072 for allosteric modulation in intracellular c-di-GMP signaling. [PDF]

open access: yesProc Natl Acad Sci U S A
Zhang Y   +18 more
europepmc   +1 more source

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