Results 141 to 150 of about 56,467 (252)
Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.This study establishes a GeLC‐MS/MS‐based serum proteomics workflow for canine oral oncology to differentiate malignancies from non‐malignant conditions. Comprehensive protein profiling, pathway analysis and protein–drug interaction mapping reveal candidate biomarkers and insights into the pathogenesis of canine oral cancers.
Sekkarin Ploypetch +4 more
wiley +1 more source
New paradigms in purinergic receptor ligand discovery. [PDF]
Neuropharmacology, 2023 Jacobson KA +3 more
europepmc +1 more source
Connexin26 and 43 play a role in regulating pro-inflammatory events in the epidermis [PDF]
, 2019 Bartholomew, Christopher +4 more
core +1 more source
Cancer Science, Volume 117, Issue 5, Page 1333-1345, May 2026.Small cell lung cancer (SCLC) actively exports ATP through PANX1 channels, triggering P2RX7‐mediated autocrine signaling and promoting tumor proliferation. Inhibition of PANX1 or P2RX7 disrupts this loop and suppresses tumor growth. ABSTRACT Small cell lung cancer (SCLC) is an aggressive malignancy with a 5‐year survival rate of less than 7%.
Takeshi Tsuruda +2 more
wiley +1 more source
Cell Proliferation, Volume 59, Issue 5, May 2026.This study identifies ferroptosis as a key driver of diabetes and its complications via iron metabolism and lipid peroxidation, elucidates organelle interactions underlying cell vulnerability, and provides insights for targeted therapies against metabolic disorders.
Zheng Wang +10 more
wiley +1 more source
Lifelong Exercise as a Modulator of CD4+ T Cell Immunometabolism
European Journal of Clinical Investigation, Volume 56, Issue 5, May 2026.Hypothetical framework illustrating how physical exercise initiated early in life acts as a critical immunomodulatory factor by promoting optimal immune function from childhood and establishing a better “immunometabolic functional peak”. This early advantage may confer sustained benefits to CD4+ T cell metabolism and immune competence across aging ...
Bruna Spolador de Alencar Silva +9 more
wiley +1 more source
Pathophysiology and Molecular Signalling in Osteoporosis: Linking Risk Factors to Bone Loss
Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.ABSTRACT Osteoporosis is a prevalent skeletal disorder characterised by progressive reduction in bone mass, microarchitectural deterioration, and increased fracture susceptibility. In India, approximately one‐third of the elderly population is affected by bone‐related disorders, and the global burden of osteoporosis continues to rise.
Pramoda G. +5 more
wiley +1 more source
Corrigendum to "New paradigms in purinergic receptor ligand discovery" [Neuropharmacology 230 (2023) 109503]. [PDF]
Neuropharmacology, 2023 Jacobson KA +3 more
europepmc +1 more source
Chromaffin Versus Platelet Granules: What We Have Learned From Chromaffin Cells for Human Studies
Journal of Neurochemistry, Volume 170, Issue 5, May 2026.Chromaffin cells and platelets both utilize exocytosis to release biogenic amines stored within large dense‐core vesicles—specifically chromaffin granules (epinephrine) and δ‐granules (serotonin). While the chromaffin cell is the foundational model for studying the secretory pathway, platelets offer a highly accessible human cell source for clinical ...
Ricardo Borges
wiley +1 more source
Journal of Cosmetic Dermatology, Volume 25, Issue 5, May 2026.ABSTRACT Background Scarring is a common dermatologic concern with both aesthetic and functional implications. Polynucleotide (PN)‐based injectables have emerged as medical devices in dermatologic practice; however, real‐world evidence on their use in scar management remains limited.
Nark Kyoung Rho +3 more
wiley +1 more source