Results 91 to 100 of about 22,737 (199)

Mechanisms of enteric neuropathy in diverse contexts of gastrointestinal dysfunction

Neurogastroenterology &Motility, Volume 37, Issue 8, August 2025.
Abstract The enteric nervous system (ENS) commands moment‐to‐moment gut functions through integrative neurocircuitry housed in the gut wall. The functional continuity of ENS networks is disrupted in enteric neuropathies and contributes to major disturbances in normal gut activities including abnormal gut motility, secretions, pain, immune dysregulation,
Julia R. Jamka, Brian D. Gulbransen
wiley   +1 more source

The role of reactive enteric glia‐macrophage interactions in acute and chronic inflammation

Neurogastroenterology &Motility, Volume 37, Issue 8, August 2025.
Abstract Enteric glia are a heterogeneous population of peripheral glia within the enteric nervous system and play pivotal roles in gut homeostasis, tissue integrity, coordination of motility, and intestinal immune responses. Under physiological conditions, they communicate with enteric neurons to control intestinal motility.
Schneider Reiner, Schneider Linda, Hamza Ebrahim, Leven Patrick, Wehner Sven   +4 more
wiley   +1 more source

Participation of the Lys313-Ile333 Sequence of the Purinergic P2X4 Receptor in Agonist Binding and Transduction of Signals to the Channel Gate [PDF]

, 2006
Zonghe Yan, Zhaodong Liang, Tomáš Obšil, Stanko S. Stojilković   +3 more
openalex   +1 more source

Use of Human In Vitro Gut Specimens for Translational Neurogastroenterology and Motility in the 21st Century

Neurogastroenterology &Motility, Volume 37, Issue 8, August 2025.
In vitro studies with GI surgical specimens or biopsy are a critical step in translating preclinical studies in animals to humans before testing potential therapeutic interventions in expensive clinical trials. Routine availability of human gut specimens, in combination with technological advances and powerful new in vitro models of the human ENS from ...
Dmitrii Pavlov, Fievos L. Christofi
wiley   +1 more source

Characterization of an alternative splice variant of human nucleoside triphosphate diphosphohydrolase 3 (NTPDase3): A possible modulator of nucleotidase activity and purinergic signaling [PDF]

, 2006
Patrick A. Crawford, Keith J. Gaddie, Thomas M. Smith, Terence L. Kirley   +3 more
openalex   +1 more source

Transcriptomic profiling of dorsal root ganglia in atopic and healthy dogs: A comparative RNA sequencing study with implications in cutaneous itch research

Veterinary Dermatology, Volume 36, Issue 4, Page 401-411, August 2025.
Background – Itch is a common symptom in skin disorders. While the neural pathways of itch transmission from the skin to the brain are well‐understood in rodents, the same pathways in dogs remain unclear. The knowledge gap hinders the development of effective treatments for canine itch‐related disorders.
Chie Tamamoto‐Mochizuki, Santosh K. Mishra   +1 more
wiley   +1 more source

Purinergic signaling during Porphyromonas gingivalis infection

Biomedical Journal, 2016
Despite recent advances unraveling mechanisms of host–pathogen interactions in innate immunity, the participation of purinergic signaling in infection-driven inflammation remains an emerging research field with many unanswered questions.
Cássio Luiz Coutinho Almeida-da-Silva, Ana Carolina Morandini, Henning Ulrich, David M. Ojcius, Robson Coutinho-Silva   +4 more
doaj  

Signal transduction mechanism of P2-purinergic receptors in thyroid cells.

, 1991
Fumikazu Okajima, Hideaki Tomura, Kōichi Sato, Martina Nazarea, Kimie Sho, Yoichi Kondo   +5 more
openalex   +1 more source

Purinergic signalling in the immune system. A brief update [PDF]

, 2007
Francesco Di Virgilio
openalex   +1 more source

Inositol Triphosphate-Mediated Ca²⁺Signals Direct Purinergic P2Y Receptor Regulation of Neuronal Ion Channels [PDF]

, 2007
Oleg Zaika, Gleb P. Tolstykh, David B. Jaffe, Mark S. Shapiro   +3 more
openalex   +1 more source