Results 11 to 20 of about 29,008 (251)
Purinergic Signaling in Spermatogenesis
Frontiers in Endocrinology, 2022 Adenosine triphosphate (ATP) serves as the essential source of cellular energy. Over the last two decades, however, ATP has also attracted increasing interest as an extracellular signal that activates purinergic plasma membrane receptors of the P2 family.
Nadine Mundt +5 more
doaj +4 more sources
Purinergic signaling in scarring
The FASEB Journal, 2016 Adenosine (ADO) and nucleotides such as ATP, ADP, and uridine 5′-triphosphate (UTP), among others, may serve as extracellular signaling molecules. These mediators activate specific cell-surface receptors - namely, purinergic 1 and 2 (P1 and P2) - to ...
Robson, Simon C. +10 more
core +6 more sources
Delineating Purinergic Signaling in Drosophila
International Journal of Molecular Sciences, 2022 Simplistic models can aid in discovering what is important in the context of normal and pathological behavior. First recognized as a genetic model more than 100 years ago, to date, fruit flies (Drosophila melanogaster) still remain an astonishingly good ...
Alberti, Francesca +7 more
core +3 more sources
Purinergic signaling in bone [PDF]
Frontiers in Endocrinology, 2012 Purinergic signaling in bone was first proposed in the early 1990s with the observation that extracellular ATP could modulate events crucial to the normal functioning of bone cells.
Rumney, Robin M.H. +3 more
core +7 more sources
Purinergic signaling in atherosclerosis
Trends in Molecular Medicine, 2015 Cell surface expression of specific receptors and ectonucleotidases makes extracellular nucleotides such as ATP, ADP, UTP, and adenosine suitable as signaling molecules for physiological and pathological events, including tissue stress and damage. Recent
Idzko M +3 more
core +5 more sources
Purinergic signaling in the cerebellum
, 2023 Purinergic signaling is a complex and evolutionarily conserved mechanism of extracellular communication involved in many physiological and pathological functions.
Wall, Mark J.
core +2 more sources
Purinergic signaling in kidney disease [PDF]
Kidney International, 2016 Nucleotides are key subunits for nucleic acids and provide energy for intracellular metabolism. They can also be released from cells to act physiologically as extracellular messengers or pathologically as danger signals.
Unwin, RJ +8 more
core +7 more sources
Purinergic signaling in the airways
Pharmacological Reviews, 2012 : Evidence for a significant role and impact of purinergic signaling in normal and diseased airways is now beyond dispute. The present review intends to provide the current state of knowledge of the involvement of purinergic pathways in the upper and ...
Burnstock, Geoffrey +7 more
core +4 more sources
In Memoriam Geoffrey Burnstock: Creator of Purinergic Signaling
Function, 2020 Geoff Burnstock (1929–2020) discovered purinergic signaling in a fastidious research that started in early 1960 and culminated in a concept of purinergic nerves in 1972.
Alexei Verkhratsky +4 more
doaj +3 more sources
Dissecting the Purinergic Signaling Puzzle
International Journal of Molecular Sciences, 2021 Purinergic signaling regulates a plethora of physiological processes and is an expanding research field [...
Raquel Pérez-Sen +3 more
core +4 more sources