Results 11 to 20 of about 932,452 (224)

Purinergic signaling in schistosomal infection

open access: yesBiomedical Journal, 2016
Human schistosomiasis is a chronic inflammatory disease caused by blood fluke worms belonging to the genus Schistosoma. Health metrics indicate that the disease is related to an elevated number of years lost-to-disability and years lost-to-life ...
Claudia Lucia Martins Silva
doaj   +4 more sources

Dissecting the Purinergic Signaling Puzzle [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
Purinergic signaling regulates a plethora of physiological processes and is an expanding research field [...
Raquel Pérez-Sen   +5 more
core   +5 more sources

Purinergic signaling in bone [PDF]

open access: yesFrontiers in Endocrinology, 2012
Purinergic signaling in bone was first proposed in the early 1990s with the observation that extracellular ATP could modulate events crucial to the normal functioning of bone cells.
Rumney, Robin M.H.   +3 more
core   +7 more sources

Purinergic signaling in infection and autoimmune disease

open access: yesBiomedical Journal, 2016
Purinergic signaling plays a key role in inflammatory processes and modulates immune responses against a variety of bacterial and eukaryotic parasites.
Luiz Eduardo Baggio Savio   +1 more
doaj   +2 more sources

Purinergic Signaling in Spermatogenesis

open access: yesFrontiers in Endocrinology, 2022
Adenosine triphosphate (ATP) serves as the essential source of cellular energy. Over the last two decades, however, ATP has also attracted increasing interest as an extracellular signal that activates purinergic plasma membrane receptors of the P2 family.
Nadine Mundt   +5 more
doaj   +4 more sources

Purinergic signaling in the cerebellum

open access: yes, 2023
Purinergic signaling is a complex and evolutionarily conserved mechanism of extracellular communication involved in many physiological and pathological functions.
Wall, Mark J., Mark J. Wall
core   +2 more sources

Delineating Purinergic Signaling in Drosophila

open access: yesInternational Journal of Molecular Sciences, 2022
Simplistic models can aid in discovering what is important in the context of normal and pathological behavior. First recognized as a genetic model more than 100 years ago, to date, fruit flies (Drosophila melanogaster) still remain an astonishingly good ...
Alberti, Francesca   +8 more
core   +3 more sources

Purinergic signaling: Diverse effects and therapeutic potential in cancer [PDF]

open access: yesFrontiers in Oncology, 2023
Regardless of improved biological insights and therapeutic advances, cancer is consuming multiple lives worldwide. Cancer is a complex disease with diverse cellular, metabolic, and physiological parameters as its hallmarks.
Jasmeet Kaur, Sanchit Dora
doaj   +2 more sources

Purinergic signaling in kidney disease [PDF]

open access: yesKidney International, 2016
Nucleotides are key subunits for nucleic acids and provide energy for intracellular metabolism. They can also be released from cells to act physiologically as extracellular messengers or pathologically as danger signals.
Unwin, RJ   +8 more
core   +6 more sources

Purinergic signaling and purine base metabolism at the crossroads between immunity, metabolism, and cancer: A review

open access: yesImmunoMedicine, 2023
In addition to its universally known role in transferring genetic material, DNA nucleotides and nucleosides are regarded as the most ancient form of extracellular signaling molecules. This unique signaling pathway was first reported by Dr.
Delaney K. Geitgey   +4 more
doaj   +2 more sources

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