Results 11 to 20 of about 932,452 (224)
Purinergic signaling in schistosomal infection
Human schistosomiasis is a chronic inflammatory disease caused by blood fluke worms belonging to the genus Schistosoma. Health metrics indicate that the disease is related to an elevated number of years lost-to-disability and years lost-to-life ...
Claudia Lucia Martins Silva
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Dissecting the Purinergic Signaling Puzzle [PDF]
Purinergic signaling regulates a plethora of physiological processes and is an expanding research field [...
Raquel Pérez-Sen +5 more
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Purinergic signaling in bone [PDF]
Purinergic signaling in bone was first proposed in the early 1990s with the observation that extracellular ATP could modulate events crucial to the normal functioning of bone cells.
Rumney, Robin M.H. +3 more
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Purinergic signaling in infection and autoimmune disease
Purinergic signaling plays a key role in inflammatory processes and modulates immune responses against a variety of bacterial and eukaryotic parasites.
Luiz Eduardo Baggio Savio +1 more
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Purinergic Signaling in Spermatogenesis
Adenosine triphosphate (ATP) serves as the essential source of cellular energy. Over the last two decades, however, ATP has also attracted increasing interest as an extracellular signal that activates purinergic plasma membrane receptors of the P2 family.
Nadine Mundt +5 more
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Purinergic signaling in the cerebellum
Purinergic signaling is a complex and evolutionarily conserved mechanism of extracellular communication involved in many physiological and pathological functions.
Wall, Mark J., Mark J. Wall
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Delineating Purinergic Signaling in Drosophila
Simplistic models can aid in discovering what is important in the context of normal and pathological behavior. First recognized as a genetic model more than 100 years ago, to date, fruit flies (Drosophila melanogaster) still remain an astonishingly good ...
Alberti, Francesca +8 more
core +3 more sources
Purinergic signaling: Diverse effects and therapeutic potential in cancer [PDF]
Regardless of improved biological insights and therapeutic advances, cancer is consuming multiple lives worldwide. Cancer is a complex disease with diverse cellular, metabolic, and physiological parameters as its hallmarks.
Jasmeet Kaur, Sanchit Dora
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Purinergic signaling in kidney disease [PDF]
Nucleotides are key subunits for nucleic acids and provide energy for intracellular metabolism. They can also be released from cells to act physiologically as extracellular messengers or pathologically as danger signals.
Unwin, RJ +8 more
core +6 more sources
In addition to its universally known role in transferring genetic material, DNA nucleotides and nucleosides are regarded as the most ancient form of extracellular signaling molecules. This unique signaling pathway was first reported by Dr.
Delaney K. Geitgey +4 more
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