Results 191 to 200 of about 932,452 (224)

Effects of nanoflubendazole and purinergic signaling modulation in overcoming neuroblastoma chemoresistance. [PDF]

open access: yesPurinergic Signal
de Mello RS   +7 more
europepmc   +1 more source

Purinergic signaling modulates CD4+ T cells with cytotoxic potential during Trypanosoma cruzi infection. [PDF]

open access: yesJ Clin Invest
Bergero G   +7 more
europepmc   +1 more source

Purinergic Signaling in the Hallmarks of Cancer

open access: yesCells, 2020
Cancer is a complex expression of an altered state of cellular differentiation associated with severe clinical repercussions. The effort to characterize this pathological entity to understand its underlying mechanisms and visualize potential therapeutic ...
Francisco G Vázquez-Cuevas   +1 more
exaly   +2 more sources
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Pain and purinergic signaling

Brain Research Reviews, 2010
A growing body of evidence indicates that extracellular nucleotides play important roles in the regulation of neuronal and glial functions in the nervous system through P2 purinoceptors. P2 purinoceptors are divided into two families, ionotropic receptors (P2X) and metabotropic receptors (P2Y).
Makoto, Tsuda   +2 more
openaire   +2 more sources

Glycogenolysis and Purinergic Signaling

2014
Both ATP and glutamate are on one hand essential metabolites in brain and on the other serve a signaling function as transmitters. However, there is the major difference that the flux in the pathway producing transmitter glutamate is comparable to the rate of glucose metabolism in brain, whereas that producing transmitter ATP is orders of magnitude ...
Leif, Hertz, Junnan, Xu, Liang, Peng
openaire   +2 more sources

Purinergic signaling in thyroid disease

Purinergic Signalling, 2022
It is known that thyroid hormones play pivotal roles in a wide variety of pathological and physiological events. Thyroid diseases, mainly including hyperthyroidism, hypothyroidism, and thyroid cancer, are highly prevalent worldwide health problems and frequently associated with severe clinical manifestations.
Ying Le, Donghui Lu, Meng Xue
openaire   +2 more sources

Purinergic Signalling in the Gut

2016
The article will begin with the discovery of purinergic inhibitory neuromuscular transmission in the 1960s/1970s, the proposal for purinergic cotransmission in 1976 and the recognition that sympathetic nerves release adenosine 5'-triphosphate (ATP), noradrenaline and neuropeptide Y, while non-adrenergic, non-cholinergic inhibitory nerve cotransmitters ...
openaire   +2 more sources

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