Results 171 to 180 of about 26,356 (209)

Mitigation of checkpoint inhibitor-induced autoimmune hemolytic anemia through modulation of purinergic signaling.

Blood
Dei Zotti F, Qiu A, D'Agati VD, Jagnarine S, Kyritsis E, Miller A, Tredicine M, Fliginger D, Stone EF, Panch S, Hudson KE.   +10 more
europepmc   +1 more source

Norepinephrine changes behavioral state via astroglial purinergic signaling

Chen AB, Duque M, Wang VM, Dhanasekar M, Mi X, Rymbek A, Tocquer L, Narayan S, Prober D, Yu G, Wyart C, Engert F, Ahrens MB.   +12 more
europepmc   +1 more source

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Purinergic Signaling in the Airways

Pharmacological Reviews, 2012
Evidence for a significant role and impact of purinergic signaling in normal and diseased airways is now beyond dispute. The present review intends to provide the current state of knowledge of the involvement of purinergic pathways in the upper and lower airways and lungs, thereby differentiating the involvement of different tissues, such as the ...
Burnstock, Geoffrey, Brouns, Inge, Adriaensen, Dirk, Timmermans, Jean-Pierre   +3 more
openaire   +3 more sources

Purinergic signaling and microglia

Pflügers Archiv - European Journal of Physiology, 2006
Microglial cells are considered as the pathologic sensors of the brain. In this paper, we review mechanisms of purinergic signaling in microglia. As ATP is not only considered as a physiological signaling substance but is also elevated in pathology, it is not surprising that microglia express a variety of P2X, P2Y and adenosin receptors.
Katrin, Färber, Helmut, Kettenmann
openaire   +2 more sources

Purinergic signaling in atherosclerosis

Trends in Molecular Medicine, 2015
Cell surface expression of specific receptors and ecto-nucleotidases makes extracellular nucleotides such as ATP, ADP, UTP, and adenosine suitable as signaling molecules for physiological and pathological events, including tissue stress and damage.
FERRARI, Davide, Vitiello L, Idzko M, la Sala A.   +3 more
openaire   +4 more sources

Pain and purinergic signaling

Brain Research Reviews, 2010
A growing body of evidence indicates that extracellular nucleotides play important roles in the regulation of neuronal and glial functions in the nervous system through P2 purinoceptors. P2 purinoceptors are divided into two families, ionotropic receptors (P2X) and metabotropic receptors (P2Y).
Makoto, Tsuda, Hidetoshi, Tozaki-Saitoh, Kazuhide, Inoue   +2 more
openaire   +2 more sources

Glycogenolysis and Purinergic Signaling

2014
Both ATP and glutamate are on one hand essential metabolites in brain and on the other serve a signaling function as transmitters. However, there is the major difference that the flux in the pathway producing transmitter glutamate is comparable to the rate of glucose metabolism in brain, whereas that producing transmitter ATP is orders of magnitude ...
Leif, Hertz, Junnan, Xu, Liang, Peng
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Purinergic signaling in thyroid disease

Purinergic Signalling, 2022
It is known that thyroid hormones play pivotal roles in a wide variety of pathological and physiological events. Thyroid diseases, mainly including hyperthyroidism, hypothyroidism, and thyroid cancer, are highly prevalent worldwide health problems and frequently associated with severe clinical manifestations.
Ying Le, Donghui Lu, Meng Xue
openaire   +2 more sources