Results 221 to 230 of about 4,754,967 (333)

Signal transduction mechanism of P2-purinergic receptors in thyroid cells.

, 1991
Fumikazu Okajima, Hideaki Tomura, Kōichi Sato, Martina Nazarea, Kimie Sho, Yoichi Kondo   +5 more
openalex   +1 more source

Purinergic signalling in the immune system. A brief update [PDF]

, 2007
Francesco Di Virgilio
openalex   +1 more source

Activation of Adenosine Phosphate Signaling Promotes Antitumor Immunity in Tumor Microenvironment and Facilitate Immunotherapy

MedComm – Oncology, Volume 4, Issue 2, June 2025.
A comprehensive analysis of the purinergic signaling mediated by P2 receptors (P2Rs) was conducted at both bulk, single‐cell, and spatial transcriptomic levels, evaluating the prognostic and predictive value of the adenosine signaling pathway in cancer immunotherapy.
Yantao Xu, Ying Wang, Zixi Jiang, Yi He, Guowei Zhou, Benliang Wei, Jiachen Liu, Xiang Chen   +7 more
wiley   +1 more source

CNMa–CNMa receptor at microbiome–gut–brain axis: novel target to regulate feeding decision

Signal Transduction and Targeted Therapy, 2021
Liyuan Peng, Hai-Yan Yin, Canhua Huang
doaj   +1 more source

Inositol Triphosphate-Mediated Ca²⁺Signals Direct Purinergic P2Y Receptor Regulation of Neuronal Ion Channels [PDF]

, 2007
Oleg Zaika, Gleb P. Tolstykh, David B. Jaffe, Mark S. Shapiro   +3 more
openalex   +1 more source

Astaxanthin Alleviates Lung Injury by Regulating Oxidative Stress, Inflammatory Response, P2X7 Receptor, NF‐κB, Bcl‐2, and Caspase‐3 in LPS‐Induced Endotoxemia

Environmental Toxicology, Volume 40, Issue 6, Page 924-934, June 2025.
ABSTRACT Sepsis remains the leading cause of multiple‐organ injury due to endotoxemia. Astaxanthin (ASTA), widely used in marine aquaculture, has an extraordinary potential for antioxidant and anti‐inflammatory activity. Purinergic receptor (e.g., P2X7R) activation is a powerful signaling in the modulation of inflammation.
Seckin Ozkanlar, Yunusemre Ozkanlar, Adem Kara, Elif Dalkilinc   +3 more
wiley   +1 more source

SorCS2 Is Important for Astrocytic Function in Neurovascular Signaling

Acta Physiologica, Volume 241, Issue 6, June 2025.
ABSTRACT Introduction The receptor SorCS2 is involved in the trafficking of membrane receptors and transporters. It has been implicated in brain disorders and has previously been reported to be indispensable for ionotropic glutamatergic neurotransmission in the hippocampus.
Christian Staehr, Hande Login, Elizaveta V. Melnikova, Magdalena Bakun, Ewelina Ziemlinska, Lilian Kisiswa, Simin Berenji Ardestani, Stella Solveig Nolte, Hans Christian Beck, Line Mathilde Brostrup Hansen, Dmitry Postnov, Alexei Verkhratsky, Anna R. Malik, Anders Nykjaer, Vladimir V. Matchkov   +14 more
wiley   +1 more source

Blockade of P2X7 receptors preserves blood retinal barrier integrity by modulating the plasmalemma vesicle‐associated protein: Implications for diabetic retinopathy

British Journal of Pharmacology, Volume 182, Issue 12, Page 2603-2620, June 2025.
Background and Purpose Plasmalemma vesicle‐associated protein (PLVAP) regulates transcytosis in vascular endothelial cells. PLVAP expression is increased in pathological conditions, such as diabetic retinopathy. P2X7 receptor antagonists have been shown to preserve blood‐retinal barrier (BRB) integrity.
Chiara Bianca Maria Platania, Francesca Lazzara, Kenneth Mitton, Naomi Haque, Wendelin Dailey, Federica Conti, Erika Giuffrida, Filippo Drago, Anca Hermenean, Cornel Balta, Hildegard Herman, Alina Ciceu, Maria Consiglia Trotta, Michele D'Amico, Giuseppe Nicosia, Settimio Rossi, Claudio Bucolo   +16 more
wiley   +1 more source

Purinergic signalling in liver diseases: Pathological functions and therapeutic opportunitiesKey points

JHEP Reports, 2020
Summary: Extracellular nucleotides, including ATP, are essential regulators of liver function and serve as danger signals that trigger inflammation upon injury.
Ping Wang, Jidong Jia, Dong Zhang
doaj  

Membrane compartments and purinergic signalling: the purinome, a complex interplay among ligands, degrading enzymes, receptors and transporters [PDF]

, 2008
Cinzia Volonté, Nadia D’Ambrosi
openalex   +1 more source