Results 131 to 140 of about 4,460,775 (261)

Spontaneous postsynaptic currents in Purkinje cells.

, 2014
(A) Representative traces of spontaneous EPSCs and IPSCs in control and Cstb−/− Purkinje cells. EPSCs are seen as inward currents (downward deflections) and IPSCs are seen as outward currents (upward deflections). Insets show single IPSCs and EPSCs taken
Saara Tegelberg (528575), Heidi Pehkonen (528578), Mikael Segerstråle (528576), Iiris Hovatta (45487), Eva Reinmaa (102391), Esa R. Korpi (121902), Outi Kopra (7927), Tarja Joensuu (528574), Paula Hakala (528577), Tomi Taira (528579), Jaana Tyynelä (245651), Anna-Elina Lehesjoki (7931)   +11 more
core   +1 more source

Longer action potential duration in the Purkinje network than in the ventricular myocardium delays retrograde activation of the human His‐Purkinje system

The Journal of Physiology, EarlyView.
Abstract figure legend Activation time (AT) maps from right ventricular apical pacing in a human ventricles model with longer action potential duration in the His‐Purkinje system (HPS) than in the myocardium (MYO). For pacing with a long S1S2 coupling interval (CI), the AT from the myocardial pacing site to the first AT of the HPS (ATMYO) is longer ...
Jason D. Bayer, Edward J. Vigmond, Ruben Coronel, Chantal E. Conrath   +3 more
wiley   +1 more source

Dysregulated TIE‐2 expression in Alzheimer's disease: Further considerations on regional specificity and shedding evidence

Brain Pathology, EarlyView.
Shi‐qi Zhang, Meichen Liu
wiley   +1 more source

The ultrarapid delayed rectifier potassium current has important functional role in the repolarization reserve of canine and human ventricular muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The ultrarapid delayed rectifier potassium current (IKur) has long been considered an atrial‐specific current with no functional role in the ventricles, despite evidence of its expression in ventricular myocytes. In the present study we challenged this prevailing concept and investigated the potential role of IKur in ventricular ...
Alaa Amin E. Abdelmagid, Aiman Saleh A. Mohammed, Gábor Mohácsi, Benjámin Paskuj, Gergő Bitay, Jakub Tomek, Sahil Dalal, Tamás Árpádffy‐Lovas, Vivien Demeter‐Haludka, István Koncz, Muhammad Naveed, László Virág, Norbert Nagy, András Varró, István Baczkó, Norbert Jost, Zsófia Kohajda, Leila Topal   +17 more
wiley   +1 more source

Müller Glia Subtypes Define Neuro‐Glial Associations and Spatial Morphogen Axes in the Zebrafish Retina

Glia, Volume 74, Issue 11, November 2026.
Zebrafish Müller glia are heterogeneous in the early larval retina. Zebrafish Müller glia subtypes define a spatial axis of retinoic acid metabolism. Neuron‐associated glial programs identified in Zebrafish Müller glia are evolutionarily conserved in mammals. ABSTRACT Müller glia are instrumental macroglia of the vertebrate retina, once thought to be a
Samuel S. Storey, Carrie L. Hehr, Shaelene Standing, Sarah McFarlane   +3 more
wiley   +1 more source

Synaptic inhibition of cerebellar Purkinje cells

, 2002
The axons of Purkinje cells are the only efferent projections of the cerebellar cortex. Synaptic inhibition exerts critical control over Purkinje cell firing activity, and thereby immediately influences cerebellar cortical output. Two inhibitory synaptic
Dean, Isabel
core  

Purkinje cells in KI mice.

, 2013
(A) A representative Purkinje cell trace (left). A representative Purkinje cell from CT and KI mice at 40× magnification (right). (B) There was no significant difference in size of the Purkinje cell soma between CT and KI mice.
David G. Standaert (177034), Yuan-Hu Jin (354041), Mark P. DeAndrade (170871), Fumiaki Yokoi (170876), Lin Zhang (8926), Kenji Hashimoto (36400), Yuqing Li (28192)   +6 more
core   +1 more source

The Role of Dendritic Spines in Water Exchange Measurements With Diffusion MRI: Time‐Dependent Single Diffusion Encoding MRI

NMR in Biomedicine, Volume 39, Issue 10, October 2026.
Geometric exchange between dendritic spines and shafts is often neglected, yet it exhibits the same signature as permeative exchange, biasing NEXI/SMEX measurements. We propose two models: an extended three‐compartment Kärger model that resolves spine–shaft exchange explicitly, and a coarse‐grained Kärger model that absorbs spines into an effective ...
Kadir Şimşek, Arthur Chakwizira, Markus Nilsson, Marco Palombo   +3 more
wiley   +1 more source

Repeated Moderate and Severe Heat Exposure Has Divergent Effects on Skeletal Muscle Mitochondrial, Proteostatic and Neuromuscular Outcomes in Mice

Acta Physiologica, Volume 242, Issue 10, October 2026.
ABSTRACT Aim Repeated heat exposure may promote adaptive remodeling or cumulative tissue burden depending on thermal dose, but its graded molecular and functional consequences during recovery remain unclear. We examined whether repeated moderate (39°C) and severe (41°C) whole‐body hyperthermia produce distinct skeletal muscle trajectories involving ...
Cansu Yakin, Cihan Suleyman Erdogan, Fatma Ozge Tuncel, Yunus Kosif, Bayram Yilmaz   +4 more
wiley   +1 more source

Death and survival of heterozygous Lurcher Purkinje cells In vitro.

, 2009
International audienceThe differentiation and survival of heterozygous Lurcher (+/Lc) Purkinje cells in vitro was examined as a model system for studying how chronic ionic stress affects neuronal differentiation and survival.
Zanjani, Hadi S, Mcfarland, Rebecca, Mariani, Jean, Cavelier, Pauline, Levenes, Carole, Bambrick, Linda L, Gautheron, Vanessa, Vogel, Michael W, Blokhin, Andrei   +8 more
core   +1 more source