Results 91 to 100 of about 6,124 (266)
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Qualitative differential games with two targets [PDF]
So-called differential games of kind (qualitative games) were considered involving two or more players each of whom possesses a target toward which he wished to steer the response of a dynamical system that was under the control of all players ...
Getz, W. M., Leitmann, G.
core +1 more source
FEBS Open Bio, EarlyView.We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley +1 more source
Game Tree Search-based Impulsive Orbital Pursuit–Evasion Game with Limited Actions
Space: Science & TechnologyThis paper focuses on the impulsive orbital pursuit–evasion game (OPEG) with limited action sets for the pursuer and evader. Initially, a mathematical model is developed by combining game theory and orbital dynamics, forming a finite-round impulsive OPEG
Wenyuan Xie, Liran Zhao, Zhaohui Dang
doaj +1 more source
An Improved Approach towards Multi-Agent Pursuit-Evasion Game Decision-Making Using Deep Reinforcement Learning. [PDF]
Entropy (Basel), 2021 Wan K, Wu D, Zhai Y, Li B, Gao X, Hu Z.
europepmc +1 more source
Pursuit-evasion in a two-dimensional domain
Ars Mathematica Contemporanea, 2017 In a pursuit-evasion game, a team of pursuers attempt to capture an evader. The players alternate turns, move with equal speed, and have full information about the state of the game. We consider the most restrictive capture condition: a pursuer must become colocated with the evader to win the game.
Beveridge, Andrew, Cai, Yiqing
openaire +3 more sources
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
Pursuer Assignment and Control Strategies in Multi-Agent Pursuit-Evasion Under Uncertainties. [PDF]
Front Robot AI, 2021 Zhang L, Prorok A, Bhattacharya S.
europepmc +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source