Results 61 to 70 of about 275,165 (298)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Pursuit-Evasion in Minimal Time with Varying Observation Constraints

Journal of Mathematical Sciences and Modelling
Optimal control problems under incomplete information, particularly in pursuit-evasion scenarios, present significant mathematical challenges. This study extends a basic time-optimal pursuit-evasion game by introducing a time-dependent observer parameter,
Özkan Değer
doaj   +1 more source

A VISIBILITY-BASED PURSUIT-EVASION PROBLEM [PDF]

International Journal of Computational Geometry & Applications, 1999
This paper addresses the problem of planning the motion of one or more pursuers in a polygonal environment to eventually "see" an evader that is unpredictable, has unknown initial position, and is capable of moving arbitrarily fast. This problem was first introduced by Suzuki and Yamashita.
Leonidas J. Guibas, Jean-Claude Latombe, Steven M. LaValle, David Lin, Rajeev Motwani 0001   +4 more
openaire   +2 more sources

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Complementarity-based reformulation and numerical method for solving pursuit-evasion differential games

SICE Journal of Control, Measurement, and System Integration
Pursuit-evasion differential games are challenging to solve both analytically and numerically, particularly as the problem dimensionality increases. These games involve bounded control inputs for each player, reflecting the limitations commonly present ...
Feni Isdaryani, Kangyu Lin, Toshiyuki Ohtsuka   +2 more
doaj   +1 more source

Pursuit–Evasion Strategies in Multi-Agent Robotic Systems: Analytical, Learning-Based, and Evolutionary Perspectives

Robotics
In studies of intelligent agents, the pursuit–evasion problem, commonly related to the predator–prey paradigm, has been used as a reference setting for examining decision-making, coordination, and adaptation in multi-agent systems. In this paper, pursuit
Alejandro Moreno-Martinez, Victor Landassuri-Moreno, Asdrúbal López-Chau, Saul Lazcano-Salas, Heriberto Casarrubias-Vargas   +4 more
doaj   +1 more source

Thompson Sampling for Pursuit-Evasion Problems

CoRR, 2018
Pursuit-evasion is a multi-agent sequential decision problem wherein a group of agents known as pursuers coordinate their traversal of a spatial domain to locate an agent trying to evade them. Pursuit evasion problems arise in a number of import application domains including defense and route planning. Learning to optimally coordinate pursuer behaviors
Zhen Li, Nicholas J. Meyer, Eric B. Laber, Robert T. Brigantic   +3 more
openaire   +2 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Collaborative Control of UAV Swarms for Target Capture Based on Intelligent Control Theory

Mathematics
Real-time dynamic capture of a single moving target is one of the most crucial and representative tasks in UAV capture problems. This paper proposes a multi-UAV real-time dynamic capture strategy based on a differential game model to address this ...
Yuan Chi, Yijie Dong, Lei Zhang, Zhenyue Qiu, Xiaoyuan Zheng, Zequn Li   +5 more
doaj   +1 more source