Results 101 to 110 of about 12,669 (162)

In Silico Hazard Assessment of Ototoxicants Through Machine Learning and Computational Systems Biology. [PDF]

Toxics
Luan S, Ji C, Zarus GM, Reh CM, Ruiz P.
europepmc   +1 more source

Berberine and berberrubine promote the expression of CYP3A4 via enhancing the binding of nuclear receptor PXR. [PDF]

BMC Pharmacol Toxicol
Xiao GM, Lu T, Zhu D, Liu MY.
europepmc   +1 more source

Pregnane X receptor (PXR) as a prognostic marker and therapeutic target in kidney renal clear cell carcinoma (KIRC) via AMPK pathway regulation. [PDF]

Sci Rep
Hu WJ, Liu M, Bao YN, Su BW, Sui X, Cui XH, Wang GY, Wen L, Wen RK, Wang WH, Yang HX, Luan ZL.   +11 more
europepmc   +1 more source

Subtle changes in ligand-receptor interactions dramatically alter transcriptional outcomes of pregnane X receptor modulators. [PDF]

Structure
Huber AD, Garcia-Maldonado E, Lin W, Poudel S, Wu J, Miller DJ, Chen T.   +6 more
europepmc   +1 more source

Molecular Signature of Cisplatin Resistance in Ovarian Cancer Identifies Therapeutic Opportunities for Re-sensitization. [PDF]

J Cancer
Mansour M, van Ginkel S, Alata M, Bani I, Elhussin I.   +4 more
europepmc   +1 more source

Gut Microbiota in the Regulation of Intestinal Drug Transporters: Molecular Mechanisms and Pharmacokinetic Implications. [PDF]

Int J Mol Sci
Rzeczycki P, Pęciak O, Plust M, Droździk M.   +3 more
europepmc   +1 more source

Cardioprotective Chinese herbs and antiretroviral drug metabolism: a systematic review of in vitro evidence. [PDF]

Front Pharmacol
Cheng WJ, Jaworowski A, Trevillyan JM, Hearps AC, Xue CC, Zhang AL.   +5 more
europepmc   +1 more source

Integrated single-cell transcriptomics and proteomics elucidate the molecular mechanisms and detoxification strategy of rifampicin-induced hepatotoxicity. [PDF]

Int J Biol Sci
Chen J, Zhang Q, Huang J, He H, Bai Y, An Y, Hao M, Zhao W, Li W, Feng S, Yang S, Liao J, Wong YK, Dai L, Du Q, Luo P, Wang J.   +16 more
europepmc   +1 more source

Gut microbial-derived indole-3-propionate improves cognitive function in Alzheimer's disease. [PDF]

Sci Adv
Li L, Jia M, Yang C, Zhao Y, Hu J, Zhao Y, Hu X, Ning F, Ding C, Li Q, Gong J, Jia X, Xu K, Wang Y, Zhou S, Deng L, Shi L, Chen X, Liu X, Liu Z.   +19 more
europepmc   +1 more source

Mechanisms and Therapeutic Advances of PXR in Metabolic Diseases and Cancer. [PDF]

Int J Mol Sci
Bi Y, Liu S, Wang L, Peng D, Chen W, Zhang Y, Wang Y.   +6 more
europepmc   +1 more source