Results 101 to 110 of about 13,268 (174)

TNFAIP1 suppresses hepatocellular carcinoma progression via the PXR/CYP3A4 signaling axis. [PDF]

Am J Cancer Res
Nie Q, Guo Y, Xiao H, Zhang D, Li H, Wang L.   +5 more
europepmc   +1 more source

IDENTIFICATION OF RESIDUES IN HUMAN PXR CRITICAL FOR THE ACTIVATION BY PXR LIGANDS

Abstracts of Annual meeting of Japanese Society for the Study of Xenobiotics, 2004
Yamagami, Saeko, Kobayashi, Kaoru, Hata, Masayuki, Hosokawa, Masakiyo, Chiba, Kan   +4 more
openaire   +1 more source

Pregnane X Receptor Regulates Human Endocrine System by Inducing Sex Hormone-Binding Globulin Expression. [PDF]

Basic Clin Pharmacol Toxicol
Ahonen MH, Konzack A, Smutny T, Pavek P, Hakkola J, Hukkanen J.   +5 more
europepmc   +1 more source

Hide and seek: targeting nuclear receptor PXR with inhibitors and PROTACs to improve drug efficacy and safety. [PDF]

Expert Opin Ther Targets
Huber AD, Chen T.
europepmc   +1 more source

In Silico Comparison of Rifampicin and 25-desacetyl Rifampicin-Induced PXR-Mediated CYP450 Transcriptional Response in 3D Primary Human Hepatocytes. [PDF]

Bull Math Biol
Kahiya ET, Smutný T, Smutná L, Duintjer Tebbens J, Pávek P, Bernhauerová V.   +5 more
europepmc   +1 more source

Artificial Intelligence in Pelvic Fracture Diagnosis and Outcome Prediction: A Systematic Review and Meta-analysis. [PDF]

Mayo Clin Proc Digit Health
Wang KJ, Abbas A, Schemitsch GW, Raleigh M, Lex JR, Felice H, Nousiainen M, Whyne C, Ravi B, Koucheki R.   +9 more
europepmc   +1 more source

Indole-acetaldehyde from Rothia mucilaginosa activates the PXR/NRF2 axis to enhance alveolar macrophage phagocytosis and protect against ARDS. [PDF]

Respir Res
Fan W, Tan T, Yang C, Cao Y, Jin C, Liu X, Shang K, Wang J, Xu J, Li Y.   +9 more
europepmc   +1 more source

[Role of PXR and CAR in cholestasis].

The Korean journal of hepatology, 2006
Cholestatic liver diseases are characterized by impairments of bile flows and accumulations of biliary constituents such as bile acids and bilirubin. The changes of phase I and II metabolism and the hepatobiliary transport system minimize cholestatic liver injury.
openaire   +1 more source

Indole-3-propionic acid links gut dysfunction to diabetic retinopathy: a biomarker and novel therapeutic approach. [PDF]

Gut
Prasad R, Adu-Rutledge Y, Ziani B, Floyd JL, Ready EL, Paul S, Sheini F, Sharma R, Rosencrans RF, Li Calzi S, Sielski MS, Medawar NG, Dutta R, Johnson EB, Qi X, Bansal M, Lamendella R, Wright JR, Verma SK, Boulton ME, Stevens BR, Vander Kooi CW, Sun RC, Oudit GY, Li Q, Grant MB.   +25 more
europepmc   +1 more source

Differential gene regulation by SR12813 and rifampicin: Insights into PXR and PPARγ activation and metabolic pathway modulation in LS180 colon cancer cells. [PDF]

Drug Metab Dispos
Brobst D, Hemsath J, Niewchas A, Pham C, Lamboglia B, Sawalha Y, Ballard C, Bodily R, Dye W, Nguyen V, Youssef A, Elliott C, Staudinger JL, Creamer BA.   +13 more
europepmc   +1 more source