The biosynthesis of pyoverdines [PDF]
Pyoverdines are fluorescent siderophores of pseudomonads that play important roles for growth under iron-limiting conditions. The production of pyoverdines by fluorescent pseudomonads permits their colonization of hosts ranging from humans to plants.
Michael T. Ringel, Thomas Brüser
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Pyoverdine aus Pseudomonas putida / Pyoverdins from Pseudomonas putida
The structures of two pyoverdins (Pp 1 and Pp 2) and one dihydropyoverdin (dihydro-Pp 2) from a strain of Pseudomonas putida have been elucidated by spectroscopic methods and degradation studies. The pyoverdins Pp 1 and Pp2 consist of a chromophore which was identified as (1 S)-5-amino-2,3-dihydro-8,9-dihydroxy-1 H-pyrimido[1,2-a]quinoline-1-carboxylic
I. Gwose, K. Taraz
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Presence of a loner strain maintains cooperation and diversity in well-mixed bacterial communities [PDF]
Cooperation and diversity abound in nature despite cooperators risking exploitation from defectors and superior competitors displacing weaker ones. Understanding the persistence of cooperation and diversity is therefore a major problem for evolutionary ...
Biernaskie, Jay +3 more
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PvdN Enzyme Catalyzes a Periplasmic Pyoverdine Modification [PDF]
Pyoverdines are high affinity siderophores produced by a broad range of pseudomonads to enhance growth under iron deficiency. They are especially relevant for pathogenic and mutualistic strains that inhabit iron-limited environments. Pyoverdines are generated from non-ribosomally synthesized highly modified peptides.
Michael T, Ringel +2 more
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Maintenance of Microbial Cooperation Mediated by Public Goods in Single- and Multiple-Trait Scenarios [PDF]
Microbes often form densely populated communities, which favor competitive and cooperative interactions. Cooperation among bacteria often occurs through the production of metabolically costly molecules produced by certain individuals that become ...
Balbontín, Roberto +3 more
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A Shift in Central Metabolism Accompanies Virulence Activation in Pseudomonas aeruginosa. [PDF]
The availability of energy has significant impact on cell physiology. However, the role of cellular metabolism in bacterial pathogenesis is not understood.
Chacko, Jenu V +4 more
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Pyoverdine-Dependent Virulence of Pseudomonas aeruginosa Isolates From Cystic Fibrosis Patients
The development of therapies that modulate or prevent pathogen virulence may be a key strategy for circumventing antimicrobial resistance. Toward that end, we examined the production of pyoverdine, a key virulence determinant, in ∼70 Pseudomonas ...
Donghoon Kang +5 more
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Total Synthesis of Pyoverdin D
Pyoverdin D is an important siderophore that is used by the human pathogen Pseudomonas aeruginosa to import iron and gain a competitive advantage. This unique partially cyclic octapeptide bears four nonproteinogenic amino acids, including (δ)N-formyl-(δ)N-hydroxy-l-ornithine, and a catechol containing chiral chromophore. Here, we report the first total
Roi Mashiach, Michael M. Meijler
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Pyoverdine and proteases affect the response of pseudomonas aeruginosa to gallium in human serum [PDF]
Gallium is an iron mimetic which has recently been repurposed as an antibacterial agent due to its capability to disrupt bacterial iron metabolism. In this study, the antibacterial activity of gallium nitrate [Ga(NO3)3] was investigated in complement ...
Bonchi, Carlo +3 more
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Diastereomeric Pyoverdin-Chromium(III) Complexes
Coordination isomeric diastereomeric Cr3+ complexes of the pyoverdin of Pseudomonas aeruginosa ATCC 15692 could be separated by chromatography and characterized by spectroscopic methods.
Herbert, Budzikiewicz +2 more
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