Indole-Acetic Acid Impairs Pseudomonas aeruginosa Virulence and Alters Lung Infection in Mice. [PDF]
Screening for anti‐virulence activity exerted by tryptophan catabolites on laboratory and clinical strains of Pseudomonas aeruginosa showed that Indoleacetic acid (IAA) inhibits motility and pigment production, downregulates PQS gene expression, while increases oxidative stress sensitivity.
Igídio CED +13 more
europepmc +2 more sources
The Burden of Antimicrobial-Resistant Pseudomonas aeruginosa Isolates in Children With Cystic Fibrosis: Molecular Characterization and Genotyping Analysis. [PDF]
This study highlights the prevalence of multidrug‐ and carbapenem‐resistant Pseudomonas aeruginosa in pediatric cystic fibrosis patients, along with the presence of carbapenemase‐encoding genes and genetic profiles, suggesting clonal spread. These findings underscore the urgent need for surveillance and strategies to combat resistant strains and ...
Jafari E +5 more
europepmc +2 more sources
Understanding the environmental factors that affect the production of virulence factors has major implications in evolution and medicine. While spatial structure is important in virulence factor production, observations of this relationship have occurred
Rebecca J. Quinn +10 more
doaj +1 more source
A Review of Pseudomonas aeruginosa Metallophores: Pyoverdine, Pyochelin and Pseudopaline
Simple Summary The human pathogen Pseudomonas aeruginosa (P. aeruginosa) causes several infections, both acute and chronic, mainly in hosts with compromised immunity and in patients suffering from cystic fibrosis.
Ghassan Ghssein, Zeinab Ezzeddine
semanticscholar +1 more source
The biosynthesis of pyoverdines [PDF]
Pyoverdines are fluorescent siderophores of pseudomonads that play important roles for growth under iron-limiting conditions. The production of pyoverdines by fluorescent pseudomonads permits their colonization of hosts ranging from humans to plants.
Michael T. Ringel, Thomas Brüser
openaire +3 more sources
Comparative genomics of isolates of a pseudomonas aeruginosa epidemic strain associated with chronic lung infections of cystic fibrosis patients [PDF]
Pseudomonas aeruginosa is the main cause of fatal chronic lung infections among individuals suffering from cystic fibrosis (CF). During the past 15 years, particularly aggressive strains transmitted among CF patients have been identified, initially in ...
A Ashish +60 more
core +12 more sources
Pyoverdine aus Pseudomonas putida / Pyoverdins from Pseudomonas putida
The structures of two pyoverdins (Pp 1 and Pp 2) and one dihydropyoverdin (dihydro-Pp 2) from a strain of Pseudomonas putida have been elucidated by spectroscopic methods and degradation studies. The pyoverdins Pp 1 and Pp2 consist of a chromophore which was identified as (1 S)-5-amino-2,3-dihydro-8,9-dihydroxy-1 H-pyrimido[1,2-a]quinoline-1-carboxylic
I. Gwose, K. Taraz
openaire +2 more sources
The pyoverdine siderophore is produced by Pseudomonas aeruginosa to access iron. Its synthesis involves the complex co-ordination of four nonribosomal peptide synthetases (NRPSs), responsible for assembling the pyoverdine peptide backbone.
Hanna Manko +5 more
semanticscholar +1 more source
Presence of a loner strain maintains cooperation and diversity in well-mixed bacterial communities [PDF]
Cooperation and diversity abound in nature despite cooperators risking exploitation from defectors and superior competitors displacing weaker ones. Understanding the persistence of cooperation and diversity is therefore a major problem for evolutionary ...
Biernaskie, Jay +3 more
core +2 more sources
Pyoverdine use for the control of passion fruit bacterial blight [PDF]
: The objective of this work was to evaluate the effect of a bacterial filtrate containing pyoverdine on the population dynamics of Xanthomonas axonopodis pv. passiflorae, and the severity of passion fruit bacterial blight.
Carla Maria Cavalcanti Ribeiro +3 more
doaj +1 more source

