Characterization of intracortical synaptic connections in the mouse anterior cingulate cortex using dual patch clamp recording [PDF]
Molecular Brain, 2009 Summary The anterior cingulate cortex (ACC) is involved in sensory, cognitive, and executive functions. Studies of synaptic transmission and plasticity in the ACC provide an understanding of basic cellular and molecular mechanisms for brain functions ...
Wu Long-Jun +4 more
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Why Neurons Have Thousands of Synapses, A Theory of Sequence Memory in Neocortex [PDF]
Frontiers in Neural Circuits, 2016 Pyramidal neurons represent the majority of excitatory neurons in the neocortex. Each pyramidal neuron receives input from thousands of excitatory synapses that are segregated onto dendritic branches.
Jeff eHawkins, Subutai eAhmad
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Thalamocortical feedback selectively controls pyramidal neuron excitability [PDF]
Nature CommunicationsThe apical dendrites of layer (L) 2/3 pyramidal neurons in the mouse somatosensory cortex integrate synaptic input from long-range projections. Among those, inputs from the higher-order thalamic posteromedial nucleus may facilitate sensory-evoked ...
Federico Brandalise +9 more
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Pyramidal neuron subtype diversity governs microglia states in the neocortex [PDF]
Nature, 2022 Kwanho Kim, Loïc Binan, Samouil L Farhi
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Action potential modulation in CA1 pyramidal neuron axons facilitates OLM interneuron activation in recurrent inhibitory microcircuits of rat hippocampus. [PDF]
PLoS ONE, 2014 Oriens-lacunosum moleculare (O-LM) interneurons in the CA1 region of the hippocampus play a key role in feedback inhibition and in the control of network activity. However, how these cells are efficiently activated in the network remains unclear.
Sooyun Kim
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Frontiers in Computational Neuroscience, 2023 Alzheimer's disease (AD) is a progressive memory loss and cognitive dysfunction brain disorder brought on by the dysfunctional amyloid precursor protein (APP) processing and clearance of APP peptides.
Justinas J. Dainauskas +7 more
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Molecular Brain, 2021 The ACC is an important brain area for the processing of pain-related information. Studies of synaptic connections within the ACC provide an understanding of basic cellular and molecular mechanisms for brain functions such as pain, emotion and related ...
Jung-Hyun Alex Lee +4 more
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Analysis of Mouse Brain Sections by Live-cell Time-lapse Confocal Microscopy
Bio-Protocol, 2023 The developing cerebral cortex of mammals is generated from nascent pyramidal neurons, which radially migrate from their birthplace in the ventral part of the neural tube to the cortical surface.
Tao Yang, Ty Hergenreder, Bing Ye
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Stereology neuron counts correlate with deep learning estimates in the human hippocampal subregions
Scientific Reports, 2023 Hippocampal subregions differ in specialization and vulnerability to cell death. Neuron death and hippocampal atrophy have been a marker for the progression of Alzheimer’s disease.
Jan Oltmer +8 more
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Occasional essay: upper motor neuron syndrome in amyotrophic lateral sclerosis [PDF]
, 2020 The diagnosis of amyotrophic lateral sclerosis (ALS) requires recognition of both lower (LMN) and upper motor neuron (UMN) dysfunction.1 However, classical UMN signs are frequently difficult to identify in ALS.2 LMN involvement is sensitively detected ...
Burke, David +6 more
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