Results 21 to 30 of about 108,821 (298)
Hyperexcitable Parvalbumin Interneurons Render Hippocampal Circuitry Vulnerable to Amyloid Beta
iScience, 2020 Summary: Parvalbumin (PV) interneuron dysfunction is associated with various brain disorders, including Alzheimer disease (AD). Here, we asked whether early PV neuron hyperexcitability primes the hippocampus for amyloid beta-induced functional impairment.
Sara Hijazi +5 more
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Weak electric fields promote resonance in neuronal spiking activity: Analytical results from two-compartment cell and network models. [PDF]
PLoS Computational Biology, 2019 Transcranial brain stimulation and evidence of ephaptic coupling have sparked strong interests in understanding the effects of weak electric fields on the dynamics of neuronal populations. While their influence on the subthreshold membrane voltage can be
Josef Ladenbauer, Klaus Obermayer
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Neuroscience Jokes. Pyramidal Neurons
, 2023 Short book with educative jokes, to make us think and remember aspects of pyramidal function and connectivity we still dont fully understand.
delgado ruz, isabel, chadderton, Paul
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Gephyrin-Lacking PV Synapses on Neocortical Pyramidal Neurons [PDF]
International Journal of Molecular Sciences, 2021 Gephyrin has long been thought of as a master regulator for inhibitory synapses, acting as a scaffold to organize γ-aminobutyric acid type A receptors (GABAARs) at the post-synaptic density. Accordingly, gephyrin immunostaining has been used as an indicator of inhibitory synapses; despite this, the pan-synaptic localization of gephyrin to specific ...
Dika A. Kuljis +7 more
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Frontiers in Neuroanatomy, 2016 This work presents PyramidalExplorer, a new tool to interactively explore and reveal the detailed organization of the microanatomy of pyramidal neurons with functionally related models. It consists of a set of functionalities that allow possible regional
Pablo eToharia +15 more
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Frontiers in Neuroanatomy, 2020 Cognitive functions such as attention and working memory are modulated by noradrenaline receptors in the prefrontal cortex (PFC). The frontal eye field (FEF) has been shown to play an important role in visual spatial attention.
Max Lee +3 more
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The enigmatic function of chandelier cells
Frontiers in Neuroscience, 2010 Chandelier (or axo-axonic) cells are one of the most distinctive GABAergic interneurons in the brain. Their exquisite target specificity for the axon initial segment of pyramidal neurons, together with their GABAergic nature, long suggested the ...
Alan R Woodruff +2 more
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Size of hippocampal pyramidal neurons in schizophrenia [PDF]
British Journal of Psychiatry, 2003 BackgroundMeta-analyses of hippocampal size have indicated that this structure is smaller in schizophrenia. This could reflect a reduction in the size of constituent neurons or a reduced number of neurons.AimsTo measure the size of hippocampal pyramidal neurons in the brains of people with and without schizophrenia.MethodPyramidal neuron size in ...
Highley, JR +4 more
openaire +4 more sources
A realistic computational model for the formation of a Place Cell
Scientific Reports, 2023 Hippocampal Place Cells (PCs) are pyramidal neurons showing spatially localized firing when an animal gets into a specific area within an environment. Because of their obvious and clear relation with specific cognitive functions, Place Cells operations ...
Camille Mazzara, Michele Migliore
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The Spatial Structure of Stimuli Shapes the Timescale of Correlations in Population Spiking Activity [PDF]
, 2012 Throughout the central nervous system, the timescale over which pairs of neural spike trains are correlated is shaped by stimulus structure and behavioral context.
Abigail Morrison +3 more
core +4 more sources