Results 151 to 160 of about 35,216 (249)

Dynamic Control of Nucleic Acids Self‐Assembly and Expression Using Photoswitches

Chemistry – A European Journal, Volume 32, Issue 31, 18 August 2026.
We review here the recent progress made in the design of molecular photoswitches, and highlight their implementation for the dynamic control over nucleic acids self‐assembly and expression. ABSTRACT Synthetic nucleic acids have become readily available and now constitute versatile building blocks in materials science—where they can be used to engineer ...
Noemí Nogal, Hugo Laigle, Maxime Mansy, Sébastien Ulrich, Mathieu Surin   +4 more
wiley   +1 more source

Targeting CDK-2 With Novel Indole-Pyrazole Hybrids: Discovery of Potent Anticancer Agents Supported by Mechanistic and In Silico Studies. [PDF]

Drug Dev Res
Eldehna WM, Elsayed ZM, Elnagar MR, Omar YM, Abdulla MH, Saleh AM, Shalabi AR, Elimam DM, Alshamari S, Fares M, Tawfik HO.   +10 more
europepmc   +1 more source

Design Rules for Tuning Thermal Lifetimes of Arylazopyrazole Photoswitches. [PDF]

ACS Cent Sci
Tiefenbacher MX, Dietschreit JCB, Axelrod S, Gómez-Bombarelli R, González L.   +4 more
europepmc   +1 more source

Chemical tools for BAZ2A/B biology: discovery of dual and BAZ2B-selective PROTAC degraders. [PDF]

RSC Med Chem
Cheng-Sánchez I, Gosselé KA, Palaferri L, Krummhaar M, Laul E, Ciulli A, Nevado C.   +6 more
europepmc   +1 more source

Synthesis and molecular docking of novel pyrazole, pyrimidine, and pyridine derivatives as potent antimicrobial, antibiofilm, and anticancer agents. [PDF]

Sci Rep
Hassan AMA, Essam ES, Hamed S, Helal MH, El-Ziaty AK, Ali RS.   +5 more
europepmc   +1 more source

Rational design, synthesis, and antimicrobial evaluation of novel 1,2,3-triazole hybrids: structure-activity relationships, molecular docking, and DFT studies. [PDF]

Sci Rep
Sallam MN, Hassan AMA, Alzahrani AYA, El-Masry HM, El-Naggar AM, Abbass EM.   +5 more
europepmc   +1 more source

Multicomponent Selective and Efficient Synthesis of Spiro[furo[2,3-<i>d</i>]pyrimidine-6,4'-pyrazole] Scaffold Under a Column Chromatography-Free Protocol at Room Temperature. [PDF]

Molecules
Elinson MN, Ryzhkova YE, Kalashnikova VM, Egorov MP.   +3 more
europepmc   +1 more source

Investigating the Inhibitory Properties of Diazo and Pyrazole-Carboxamide-Linked Benzenesulfonamides Against Carbonic Anhydrase Isoforms I, II, IX, and XII. [PDF]

ChemMedChem
Akocak S, Lolak N, Ammara A, Gürbüz G, Bozgeyik I, Taşdemir D, Hashem H, Bräse S, Supuran CT.   +8 more
europepmc   +1 more source

Design, synthesis, biological assessment, and integrated computational analysis of new pyrazole-based antimicrobial candidates. [PDF]

Sci Rep
El-Helw EAE, Hamed S, El-Ziaty AK, Alzahrani AYA, Ramadan SK.   +4 more
europepmc   +1 more source

Synthesis, Photophysical Properties, and Primary Biological Characteristics of Meso-pyrazole-substituted BODIPY Derivatives. [PDF]

J Fluoresc
Coşkun Z, Coşar E, Aksoy BT, Kazan HH, Sengul IF, Çoşut B.   +5 more
europepmc   +1 more source