Results 161 to 170 of about 36,678 (260)

Computational, In Vitro, and In Vivo Evaluation of Benzimidazole-Pyrazole Hybrid Scaffolds as Multi-Target Anti-Ulcer Agents. [PDF]

Chem Biodivers
Kharl HAA, Malik A, Nadeem H, Ola MS, Aiman S, Khan AU, Farooq MA, Muzaffar H, Masaud SM.   +8 more
europepmc   +1 more source

Exploring Novel Indazole and Pyrazole Nucleoside Analogues: Enzymatic Synthesis, Characterization, and Biological Evaluation. [PDF]

Int J Mol Sci
Mironov AF, Eletskaya BZ, Antonov KV, Paramonov AS, Esipov RS, Konstantinova ID, Andreevskaya SN, Smirnova TG, Karpenko IL, Sokhraneva VA, Zhivotova IS, Kochetkov SN, Khandazhinskaya AL, Matyugina ES.   +13 more
europepmc   +1 more source

Biological Evaluation, Molecular Docking, MD Simulation Study and Synthesis of (Z)‐N’‐(3‐phenoxybenzylidene)‐2‐(substituted‐amino aryl) Acetohydrazid

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 10, October 2026.
Synthesis and biological evaluation (antibacterial, antifungal, anti‐tuberculosis, antiprotozoal) and in silico molecular docking of biphenyl ether based Schiff's base analogues. ABSTRACT In order to investigate their possible biological activity, a number of new Schiff base compounds based on diaryl ether, specifically 2‐(substituted‐arylamino)‐N′‐(3 ...
Navin B. Patel, Deepti S. Ghaisas, Vatsal M. Patel, Faiyazalam M. Shaikh, Mohit Agrawal, Mohd Imran, Gildardo Rivera, Hetal I. Soni   +7 more
wiley   +1 more source

Green Synthesis, In Silico Molecular Docking, and Evaluation of Pyrazole Derivatives for Their Antifungal and Antinemic Activity. [PDF]

Chem Biodivers
Kumar R, Tripathi K, Kaushik P, Kumar V, Godara R, Mondal PC, Misra SR, Pankaj, Rana VS, Shanmugam V, Khatri D, Shakil NA.   +11 more
europepmc   +1 more source

Iron and Other Metal Ions in Human Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley   +1 more source

Synthesis and Reactions of Hydrazine Trifluoroborate Salts. [PDF]

Org Lett
Ballerini L, Zhao W, Tarasewicz A, Méndez M, Harrity JPA.   +4 more
europepmc   +1 more source

2‐Chloro‐5‐(trifluoromethyl)aniline‐Derived Schiff Base Palladium(II) Complexes: From Molecular Design to Acute Toxicity Assessment

ChemistryOpen, Volume 15, Issue 10, October 2026.
Four new Schiff bases derived from 2‐chloro‐5‐(trifluoromethyl)aniline and their corresponding palladium(II) complexes were obtained and analyzed by multiple spectroscopic techniques. Single‐crystal X‐ray diffraction elucidated the structures of all the ligands and complexes 2 and 4. Their toxicity was assessed on Triticum aestivum L.
Andreea Elena Ştefan, Cristina Elena Dinu‐Pîrvu, Sergiu Shova, Ştefania Felicia Bărbuceanu, Teodora Venera Apostol, Diana Carolina Ilieş, Mihaela Badea, Mihaela Dinu, Robert Viorel Ancuceanu, Doina Drăgănescu, Elena Pahonţu   +10 more
wiley   +1 more source

Store-Operated Calcium Entry Inhibitors: Structural Diversity, Mechanisms of Action, and Optimization Strategies. [PDF]

Int J Mol Sci
Zakharova AA, Grekhnev DA, Kaznacheyeva EV, Vigont VA.   +3 more
europepmc   +1 more source

Targeting CDK-2 With Novel Indole-Pyrazole Hybrids: Discovery of Potent Anticancer Agents Supported by Mechanistic and In Silico Studies. [PDF]

Drug Dev Res
Eldehna WM, Elsayed ZM, Elnagar MR, Omar YM, Abdulla MH, Saleh AM, Shalabi AR, Elimam DM, Alshamari S, Fares M, Tawfik HO.   +10 more
europepmc   +1 more source

Estradiol—PGC‐1 signaling in mitochondrial health: Implications for perimenopause and cardiovascular disease

Physiological Reports, Volume 14, Issue 20, October 2026.
Abstract Cardiovascular disease (CVD) is the leading cause of death in aging women. While CVD etiology is multifactorial, mitochondrial dysfunction, characterized by reduced content, impaired energy production, and increased oxidative stress, is an underlying contributor.
Alyssa L. Parten, Glenn C. Rowe
wiley   +1 more source