Synthesis, characterization, docking and <i>in vitro</i> evaluation of new pyrazole-carboxylate derivatives as antibacterial, anticancer and anti-inflammatory agents. [PDF]
Menezes RA +7 more
europepmc +1 more source
Three privileged scaffolds, one pipeline: chalcones, pyrazolines and pyrazoles in drug discovery and fluorescent sensing. [PDF]
Ciupa A.
europepmc +1 more source
Photochemisch erzeugte Oxetane als Schlüssel zur endergonen Cyclopropansynthese
Eine neuartige Oxetan‐zu‐Cyclopropan‐Umlagerung eröffnet einen atomökonomischen Zugang zu dicht funktionalisierten Cyclopropanen aus Furanen und photochemisch aktivierten Aldehyden. Die erhaltenen Strukturen erschließen komplexe bioaktive Motive und fungieren als vielseitige Plattform für die asymmetrische Cyclopropansynthese.
Tim Köglmeier +2 more
wiley +1 more source
Novel benzofuran-furan-pyrano[2,3-<i>c</i>]pyrazole hybrids as potential anticancer agents: design, synthesis, <i>in silico</i> profiling, and multi-mechanistic biological evaluation. [PDF]
Hutanu ED +5 more
europepmc +1 more source
Design, synthesis and antifungal activity of pyrazole ester derivatives. [PDF]
Shen Y +4 more
europepmc +1 more source
Photogenerated Oxetanes as a Gateway to Uphill Cyclopropanation
An atom‐economical route to densely functionalized cyclopropanes from furans and photochemically activated aldehydes is enabled by a unique oxetane‐to‐cyclopropane rearrangement. These cyclopropanes can be used to access complex bioactive scaffolds and serve as a platform for asymmetric cyclopropane synthesis.
Tim Köglmeier +2 more
wiley +1 more source
Green Synthesis, In Silico Molecular Docking, and Evaluation of Pyrazole Derivatives for Their Antifungal and Antinemic Activity. [PDF]
Kumar R +11 more
europepmc +1 more source
Synthesis and Reactivity of 3‐Aminosydnones in Cycloaddition Reactions With Alkynes
The synthesis, functionalization, and reactivity as dipoles of 3‐aminosydnones have been investigated. These neglected compounds undergo smooth cycloaddition reactions with strained alkynes, leading to 1‐aminopyrazoles. ABSTRACT We present in this article the synthesis, functionalization, and properties of 3‐aminosydnones, a forgotten class of ...
Apolline Dominic +7 more
wiley +1 more source
The Stabilization of High‐Nitrogen Systems: 10 Catenated Nitrogen Chain
Improving the understanding of high‐nitrogen materials. ABSTRACT High‐nitrogen materials have attracted intense interest in recent decades due to their unique chemical, physical, and biological properties. Stabilizing high‐nitrogen materials is often challenging as they become more unstable with increasing nitrogen catenation and nitrogen mass ...
Nicholas F. Scherschel +3 more
wiley +1 more source
Synthesis and Reactions of Hydrazine Trifluoroborate Salts. [PDF]
Ballerini L +4 more
europepmc +1 more source

