Crystal structure of [1-(3-chlorophenyl)- 5-hydroxy-3-methyl-1H-pyrazol-4-yl](p-tolyl) methanone [PDF]
, 2015 RK acknowledges the Department of Science & Technology for the single-crystal X-ray diffractometer sanctioned as a National Facility under Project No.
Gupta, V.K. +4 more
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Advanced Science, EarlyView.An electrochemical Hofmann rearrangement of amide involving amine or other amide nucleophiles has been developed. The use of NaI guarantees the feasibility and compatibility of the electrosynthesis protocol, which enables highly chemoselective synthesis of unsymmetrical N‐acylureas from two different amides, as well as the production of unsymmetrical ...
Xue‐Qing Mou +9 more
wiley +1 more source
Discovery of a Potent Fluorescence Polarization Probe for Identifying USP1 Allosteric Inhibitors
Advanced Science, EarlyView.This study presents the first ubiquitin‐specific protease 1 (USP1) allosteric fluoroprobe and fluorescence polarization assay, enabling the differentiation of allosteric and catalytic site inhibitors. Further, a novel class of tetrahydroisoquinoline‐based USP1 inhibitors is designed, with compound 14a (USP1 IC50 = 29.9 nM) showing strong selectivity ...
Jiawei Cheng +12 more
wiley +1 more source
Designed Monomers and PolymersA new class of biologically active polyazomethine/pyrazole and their related nanocomposites, polyazomethine/pyrazole/zinc oxide nanoparticles, have been successfully synthesized through the polycondensation technique in the form of polyazomethine ...
Aqilah A. Hakami +3 more
doaj +1 more source
Synthesis of an arginine mimic for an antifungal octapeptide library : this thesis is presented in partial fulfilment of the requirements for the degree of Master of Science in Chemistry at Massey University, Palmerston North, New Zealand [PDF]
, 2008 A family of bioactive antifungal octapeptides has been established¹⁻³. The template for this library is based on peptides composed of two predefined amino acids, three arginines, and three unknown components. The arginine contains a guanidino group (pKa =
Sun, Hao
core
Effect of ligand methylation on the spin-switching properties of surface-supported spin-crossover molecules [PDF]
, 2019 X-ray absorption spectroscopy investigations of the spin-state switching of spin-crossover (SCO) complexes adsorbed on a highly-oriented pyrolytic graphite (HOPG) surface have shown so far that HOPG is a promising candidate to realize applications such ...
Arruda, Lucas M. +9 more
core +1 more source
Preparation of multiblock copolymers via step-wise addition of l-lactide and trimethylene carbonate. [PDF]
, 2018 Poly(l-lactide) (PLA) is a bioderived and biodegradable polymer that has limited applications due to its hard and brittle nature. Incorporation of 1,3-trimethylene carbonate into PLA, in a block copolymer fashion, improves the mechanical properties ...
Abubekerov, Mark +5 more
core +1 more source
Crystal structure and molecular docking studies of new pyrazole-4-carboxamides
Heterocyclic Communications, 2019 Two pyrazol-4-carboxamides, 3-(difluoromethyl)-N-(mesitylcarbamoyl)-1-methyl-1H-pyrazole-4-carboxa-mide (7a) and 3-(difluoromethyl)-N-((3,5-dimethylphenyl) carbamoyl)-1-methyl-1H-pyrazole-4-carboxamide (7b) were synthesized and their structures were ...
Qiao Li +6 more
doaj +1 more source
Seven coordinate molybdenum and tungsten complexes containing Tpm and Tpm derivatives and the impact of ligand substitution on NMR chemical shifts [PDF]
, 2019 A series of known and new seven coordinate molybdenum and tungsten complexes of tris(pyrazolyl)methane (Tpm) and substituted Tpm, [TpmM(CO)3X]+, have been synthesized. Depending on the identity of X, (bromo, iodo, hydrido) and the substitution of the Tpm
Seager, Cole
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Predicting Solid-State Heats of Formation of Newly Synthesized Polynitrogen Materials by Using Quantum Mechanical Calculations [PDF]
, 2008 We present density functional theory level predictions and analysis of the basic properties of newly synthesized high-nitrogen compounds together with 3,6-bis(2H-tetrazol-5-yl)-1,2,4,5-tetrazine (BTT) and 3,3′-azobis(6-amino-1,2,4,5-tetrazine) (DAAT ...
Abou-Rachid, H. +5 more
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