Results 41 to 50 of about 36,678 (260)

Origin of Enhanced Efficiency and Reduced Roll‐Off in Organic Light‐Emitting Diodes Based on Pt(II) Complexes

Advanced Science, EarlyView.
Controlled Pt–Pt fine structure in square‐planar Pt(II) complexes governs metal–metal‐to‐ligand charge‐transfer (MMLCT) state formation, exciton dynamics, and organic light‐emitting diode performance. Short Pt–Pt contacts in Pt(fppz)2 enable coherent metal–metal coupling, sub‐microsecond emission and an external quantum efficiency of 29%, whereas ...
Atul Shukla, Sarah K. M. McGregor, Julian A. Steele, Innes K. Gale, Kiyoshi Miyata, Monirul Hassan, Christian McDonald, Romain J. Lepage, Eduardo Solano, Pilankatta K. Ramya, Cherumuttathu H. Suresh, Takumi Ehara, Chihaya Adachi, Ken Onda, Shih‐Chun Lo, Ebinazar B. Namdas   +15 more
wiley   +1 more source

Synthesis, Structure and Antileishmanial Evaluation of Endoperoxide–Pyrazole Hybrids

Molecules, 2022
Leishmaniases are among the most impacting neglected tropical diseases. In attempts to repurpose antimalarial drugs or candidates, it was found that selected 1,2,4-trioxanes, 1,2,4,5-tetraoxanes, and pyrazole-containing chemotypes demonstrated activity ...
Patrícia S. M. Amado, Inês C. C. Costa, José A. Paixão, Ricardo F. Mendes, Sofia Cortes, Maria L. S. Cristiano   +5 more
doaj   +1 more source

Lewis Acid‐Catalyzed Strain‐Enabled (3+3) Annulation of Bicyclo[1.1.0]Butanes With Indolylalcohols: Synthesis of Indole‐Fused Aza‐Bicyclo[3.1.1]Heptanes

Advanced Science, EarlyView.
Bicyclo[1.1.0]butanes undergo a Lewis acid‐catalyzed formal (3 + 3) annulation with indolyl alcohols to furnish indole‐fused aza‐bicyclo[3.1.1]heptanes. Strain‐release‐driven C‐C bond formation, followed by C‐N bond formation via ring expansion, enables the rapid assembly of rigid, sp3‐rich bicyclic architectures under mild reaction conditions ...
Mainak Dey, Tuhin Subhra Das Mahapatra, Pragya Sharma, Manoj V. Mane, Chinmoy Kumar Hazra   +4 more
wiley   +1 more source

Quantum-chemistry informed Bayesian optimization for the accelerated discovery of novel pyrazole-based energetic materials

Artificial Intelligence Chemistry
Developing high-performance Energetic Materials (EMs) with small environmental footprint remains a critical challenge for both civilian and military applications.
Muktar Musa Ibrahim, Adamu Uzairu, Gideon Adamu Shallangwa, Muhammad Tukur Ibrahim   +3 more
doaj   +1 more source

Styrylpyrazoles: Properties, Synthesis and Transformations

Molecules, 2020
The pyrazole nucleus and its reduced forms, pyrazolines and pyrazolidine, are privileged scaffolds in medicinal chemistry due to their remarkable biological activities. A huge number of pyrazole derivatives have been studied and reported over time.
Pedro M. O. Gomes, Pedro M. S. Ouro, Artur M. S. Silva, Vera L. M. Silva   +3 more
doaj   +1 more source

DataSheet1_Synthesis of Novel Azo-Linked 5-Amino-Pyrazole-4-Carbonitrile Derivatives Using Tannic Acid–Functionalized Silica-Coated Fe3O4 Nanoparticles as a Novel, Green, and Magnetically Separable Catalyst.PDF

, 2021
Tannic acid–linked silica-coated Fe3O4 nanoparticles (Fe3O4@SiO2@Tannic acid) were prepared and characterized by transmission electron microscope (TEM), field emission scanning electron microscope (FE-SEM), X-ray powder diffraction (XRD), X-ray ...
Mohammad Nikpassand (805441), Farhad Sedighi Pashaki (11685868)   +1 more
core   +1 more source

Über die Bindungsstelle hinausgedacht: Ein sich selbsteinkapselnder Kinase‐Inhibitor modelliert seine Bindetasche und erzielt so Selektivität

Angewandte Chemie, EarlyView.
Um außergewöhnlich wirksame Wirkstoffe zu entwickeln, ist es erforderlich, über die Bindungsstelle hinaus zu denken. Diese Arbeit zeigt, dass die auf den ersten Blick kontraintuitive Adressierung einer konservierten Region der Kinase zu einer hochselektiven Bindung führen kann.
Nico J. Seidler, Monica R. MacDonald, Athina A. Moschopoulou, Sahba Cunningham, Tess M. Weber, Nader N. Nasief, Lorenz Mayer, Frederik W. Hacker, Ekaterina Hermann, Mareike B. Möllers, Yuliia Skliarenko, Tahereh Damghani, Abid N. Manzar, Kaly S. Lin, Ramona Rudalska, Marcia I. Goettert, Lars Zender, Daniel Dauch, Michael Forster, Stefan A. Laufer, David E. Heppner   +20 more
wiley   +1 more source

1,2-Bis(boronate) Arenes by Borylation Directed Borylation. [PDF]

Angew Chem Int Ed Engl
Boron electrophiles derived from tetrabromo‐pyrazaboles and AlCl3 affect the regioselective vicinal double C–H borylation of a range of arenes and polycyclic aromatic hydrocarbons (PAHs). A subsequent pinacol installation step then affords the vicinal bis‐boronate ester‐substituted arene/PAH.
Schellbach AV, Cross MJ, Noone E, Anstöter CS, Ingleson MJ.   +4 more
europepmc   +3 more sources

A new polyazomethine-based pyrazole moiety and its reinforced nanocomposites @ ZnO for antimicrobial applications

Designed Monomers and Polymers
A new class of biologically active polyazomethine/pyrazole and their related nanocomposites, polyazomethine/pyrazole/zinc oxide nanoparticles, have been successfully synthesized through the polycondensation technique in the form of polyazomethine ...
Aqilah A. Hakami, Hajar S. Alorfi, Thoraya A. Farghaly, Mahmoud A. Hussein   +3 more
doaj   +1 more source

Facile synthesis of novel α-methylene-pyrazole-carboxylate substituted imines and trans-β-lactams: Versatile synthons for diverse heterocyclic molecules

, 2018
A simple, facile, and high yielding stereoselective approach for the integration of α-methylene-pyrazole-carboxylates at the β-lactam nucleus is described.
Aman Bhalla (3832465), Shiwani Berry (4404241), Shamsher S. Bari (3832459), Qudrat Hundal (5008523), Dipika Narula (5008526)   +4 more
core   +1 more source