Results 61 to 70 of about 20,186 (218)

Dynamic Control of Nucleic Acids Self‐Assembly and Expression Using Photoswitches

open access: yesChemistry – A European Journal, EarlyView.
We review here the recent progress made in the design of molecular photoswitches, and highlight their implementation for the dynamic control over nucleic acids self‐assembly and expression. ABSTRACT Synthetic nucleic acids have become readily available and now constitute versatile building blocks in materials science—where they can be used to engineer ...
Noemí Nogal   +4 more
wiley   +1 more source

Aqua(4-nitrophthalato)bis[2-(1H-pyrazol-3-yl)pyridine]zinc(II) hemihydrate

open access: yesActa Crystallographica Section E, 2011
In the title compound, [Zn(C8H3NO6)(C8H7N3)2(H2O)]·0.5H2O, the ZnII atom shows a distorted octahedral ZnN4O2 coordination environment and is bonded to two 3-(2-pyridyl)-1H-pyrazole ligands via the N atoms, one monodentate 4-nitrophthalate ligand
Hong Wei, Ji-Li Zhao, Lei Ni
doaj   +1 more source

Synthesis and Reactivity of 3‐Aminosydnones in Cycloaddition Reactions With Alkynes

open access: yesChemistry – A European Journal, EarlyView.
The synthesis, functionalization, and reactivity as dipoles of 3‐aminosydnones have been investigated. These neglected compounds undergo smooth cycloaddition reactions with strained alkynes, leading to 1‐aminopyrazoles. ABSTRACT We present in this article the synthesis, functionalization, and properties of 3‐aminosydnones, a forgotten class of ...
Apolline Dominic   +7 more
wiley   +1 more source

Current progress in synthetic and medicinal chemistry of pyrazole hybrids as potent anticancer agents with SAR studies

open access: yesFuture Journal of Pharmaceutical Sciences
Background One of the most serious and potentially hazardous diseases that trouble the globe today is cancer. Among various cancer treatment options, chemotherapy is currently one of the most efficient ways to remove cancer.
Bhupender Nehra   +3 more
doaj   +1 more source

Adsorption of Mn2+, Co2+, and Ni2+ in MOF-808 and pyrazole-modified MOF-808: Selectivity trends assessed with microcalorimetry and spectroscopic analysis

open access: yesChemical Engineering Journal Advances
Zirconium(IV)-based metal-organic framework (MOF) MOF-808 and pyrazole-functionalized MOF-808 were investigated for the selective adsorption of Mn2+, Co2+, and Ni2+, the key components of lithium-ion battery cathodes.
Boyoung Song   +5 more
doaj   +1 more source

Mechanochemical Amidation Mediated by 1,1’‐Oxalyldiimidazole for the Synthesis of Agrochemicals

open access: yesChemistry – A European Journal, EarlyView.
Mechanochemical amidation using 1,1'‐oxalyldiimidazole (ODI) overcomes limitations of 1,1’‐carbonyl diimidazole (CDI) as coupling agent by enabling the efficient mechanochemical synthesis of three marketed agrochemicals from deactivated carboxylic acids.
Andrea Casagrande   +6 more
wiley   +1 more source

Grafting of multiwalled carbon nanotubes with pyrazole derivatives: characterization, antimicrobial activity and molecular docking study

open access: yesInternational Journal of Nanomedicine, 2019
Nadia Hanafy Metwally,1 Gamal Riad Saad,1 Esraa Azmy Abd El-Wahab21Chemistry Department, Faculty of Science, Cairo University, Giza, Egypt; 2Department of Engineering Mathematics and Physics, Faculty of Engineering Shoubra, Benha UniversityCorrespondence:
Metwally NH, Saad GR, Abd El-Wahab EA
doaj  

tert-Butyl 4-{[5-(4-chlorophenyl)-1-(4-fluorophenyl)-1H-pyrazol-3-yl]carbonyl}piperazine-1-carboxylate

open access: yesActa Crystallographica Section E, 2010
In the title pyrazole derivative, C25H26ClFN4O3, both benzene rings are twisted out of the plane through the pyrazole ring, with dihedral angles of 67.62 (10) and 27.63 (10)° for the fluoro- and chloro-substituted rings ...
Seik Weng Ng   +4 more
doaj   +1 more source

Precision Chemistry for Protein Lysine Modification

open access: yesChemistry – A European Journal, EarlyView.
Selective modification of lysine residues is challenging due to their similar intrinsic reactivity. Inspired by enzymatic recognition, ligand‐guided electrophiles enable site‐selective labeling and functionalization, while ligand‐guided catalyses achieve regioselective installation of bio‐relevant post‐translational modifications.
Mayu Onoda, Motomu Kanai
wiley   +1 more source

Fluorogenic Sydnones for Bioorthogonal Labeling of DNA

open access: yesChemistry – A European Journal, EarlyView.
Conjugates of sydnones with cyanine‐styryl dyes combine bioorthogonal reactivity with fluorogenicity. The reactivity with bicyclo[6.1.0]non‐4‐yne (BCN)‐modified DNA showed second‐order rate constants of up to k2 = 2,300 M−1s−1 and fluorescence turn‐on by one magnitude of order.
Kerstin Müller   +1 more
wiley   +1 more source

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