Results 21 to 30 of about 36,678 (260)
Вплив похідних піразолу на ріст і розвиток рослин в умовах in vivo та in vitro
Доповiдi Нацiональної академiї наук України, 2021 Досліджено вплив синтетичних низькомолекулярних сполук — похідних піразолу — на ріст і розвиток рослин томата (Solanum lycopersicum L.) сорту Money Maker в умовах in vivo та in vitro. Встановлено, що найбільш виражену активність в умовах in vivo виявляє
I.V. Mohilnikova +5 more
doaj +1 more source
Synthesis and SAR studies of pyrazole-3-carboxamides and -3-carbonyl thioureides including chiral moiety: Novel candidates as antibacterial agents [PDF]
Journal of the Serbian Chemical Society, 2018 A series of tetrasubstituted pyrazole-3-carboxamides (3a–c) and pyrazole- 3-carbonyl thioureides (6a–c) were synthesized and their structures characterized by IR, NMR and elemental analysis.
Bildirici Ishak +3 more
doaj +1 more source
Novel Pyrazole Derivatives Having Mono/Di Chiral Centered Group as Organocatalyst for Henry Reaction
Macedonian Journal of Chemistry and Chemical Engineering, 2020 The chiral substituted pyrazole-3-carboxamides (4a-c), pyrazole-3-carboxylates (5a-c), pyrazole-3-thioureides (7a-c) and pyrazole-3,4-dicarboxamides (10a-c) were prepared via the pyrazolo-3-chlorocarbonyl 2, pyrazolo-3,4-dicarboxy methyl ester 3 with ...
Adnan Çetin +2 more
doaj +1 more source
Pyrene-linked heterocyclic pyrazoles: Synthesis, antimicrobial screening, and in silico molecular insights. [PDF]
Smart MolA series of novel pyrene‐linked heterocyclic pyrazoles were synthesized and structurally characterized. The compounds were evaluated for antimicrobial activity against selected bacterial and fungal strains, showing promising inhibitory effects. Molecular docking studies provided insights into binding interactions and structure–activity relationships ...
Kasundra DV, Patel PN.
europepmc +2 more sources
2,2′-(1-Phenyl-1H-pyrazole-3,5-diyl)diphenol [PDF]
, 2009 The title compound, C21H16N2O2, was derived from 1-(2-hydroxyphenyl)-3-(-methoxyphenyl)propane-1,3-dione. The molecular structure of the title compound is stabilized by an intramolecular O-H...N hydrogen bond. The dihedral angle between the hydroxyphenyl
Bolte, Michael +9 more
core +1 more source
Angewandte Chemie, EarlyView.Lenacapavir, the first‐in‐class drug targeting HIV‐1 capsid, is a breakthrough drug in HIV‐1 treatment and prophylaxis. However, a single M66I mutation confers complete viral resistance to lenacapavir. We report herein the design and synthesis of innovative R2 analogs demonstrating low nM potency against HIV‐1 M66I and excellent pharmacokinetics in ...
Nicolas Jamey +13 more
wiley +2 more sources
, 2021 Herein we introduce a transition-metal-free protocol that involves a commercially available, inexpensive pyrazole molecule to conduct C–C cross-coupling reactions at room temperature via a radical pathway.
Abhishek Kundu +7 more
core +1 more source
Cobalt‐Catalyzed C─N Bond Formation via Metal‐Hydride Hydrogen Atom Transfer (MHAT)
Angewandte Chemie, EarlyView.Cobalt‐catalyzed metal‐hydride hydrogen atom transfer (Co‐MHAT) converts simple alkenes into C─N bonds under mild, near‐neutral conditions. A shared Co─H‐initiated radical/organocobalt intermediate is channeled into radical trapping, radical‐polar crossover, or radical ligand transfer, unifying hydroamination, hydroazidation, hydroamidation, and remote
Arman Khosravi, Ming‐Yu Ngai
wiley +2 more sources
, 2022 Succinate dehydrogenase (SDH) inhibitor is one of the research hotspots for the development of fungicides. Herein, we describe the design and synthesis of N-methoxy-(biphenyl-ethyl)-pyrazole-carboxamide derivatives with enhanced fungicidal activity by ...
Qiang Lu (49688) +6 more
core +1 more source