Results 21 to 30 of about 35,216 (249)
, 2021 Herein we introduce a transition-metal-free protocol that involves a commercially available, inexpensive pyrazole molecule to conduct C–C cross-coupling reactions at room temperature via a radical pathway.
Abhishek Kundu +7 more
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Frontiers in Pharmacology, 2020 A series of trifluoromethylated pyrazole thiosemicarbazone, trifluromethylated pyrazole isothiosemicarbazone, and trifluoromethylated pyrazole 2-amino-1,3,4-thiadiazole hybrids were synthesized and evaluated in vitro against the promastigote form of ...
Jeniffer do Nascimento Ascencio Camargo +7 more
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Frontiers in Oncology, 2022 As pyrazole and its derivatives have a wide range of biological activities, including anticancer activity, the design of novel pyrazole derivatives has emerged as an important research field.
Minsung Kang +13 more
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Recent Applications of the Multicomponent Synthesis for Bioactive Pyrazole Derivatives
Molecules, 2022 Pyrazole and its derivatives are considered a privileged N-heterocycle with immense therapeutic potential. Over the last few decades, the pot, atom, and step economy (PASE) synthesis of pyrazole derivatives by multicomponent reactions (MCRs) has gained ...
Diana Becerra +2 more
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Beilstein Journal of Organic Chemistry, 2023 An operationally simple and metal-free approach is described for the synthesis of pyrazole-tethered thioamide and amide conjugates. The thioamides were generated by employing a three-component reaction of diverse pyrazole C-3/4/5 carbaldehydes, secondary
Shubham Sharma +8 more
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Current status of pyrazole and its biological activities
Journal of Pharmacy and Bioallied Sciences, 2016 Pyrazole are potent medicinal scaffolds and exhibit a full spectrum of biological activities. This review throws light on the detailed synthetic approaches which have been applied for the synthesis of pyrazole.
Mohd Javed Naim +4 more
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Hierarchy of Intermolecular Interactions in Highly Luminescent Pyrenyl-Pyrazole-Aldehyde
, 2022 The intricacies of the crystal structure and the hierarchy of intermolecular interactions in a highly luminescent pyrene-pyrazole-aldehyde (PPPcA) are hereby analyzed by means of experimental charge density analysis, periodic DFT calculations, and high ...
Daniel Mariusz Tchoń (14308901) +5 more
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Acta Crystallographica Section E: Crystallographic Communications, 2015 In the pyrazole molecule of the title solvate, C15H13BrN4O2·C2H6OS, the dihedral angle between the benzene ring and the mean plane of the dihydropyrano[2,3-c]pyrazole ring system [r.m.s deviation = 0.031 (2) Å] is 86.71 (14)°.
Sammer Yousuf +3 more
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, 2022 Succinate dehydrogenase (SDH) inhibitor is one of the research hotspots for the development of fungicides. Herein, we describe the design and synthesis of N-methoxy-(biphenyl-ethyl)-pyrazole-carboxamide derivatives with enhanced fungicidal activity by ...
Qiang Lu (49688) +6 more
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