Results 11 to 20 of about 7,294 (164)
In the title pyrazole derivative, C25H26ClFN4O3, both benzene rings are twisted out of the plane through the pyrazole ring, with dihedral angles of 67.62 (10) and 27.63 (10)° for the fluoro- and chloro-substituted rings ...
Seik Weng Ng +4 more
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Tricyclic Pyrazole-Based Compounds as Useful Scaffolds for Cannabinoid CB1/CB2 Receptor Interaction
Cannabinoids comprise different classes of compounds, which aroused interest in recent years because of their several pharmacological properties. Such properties include analgesic activity, bodyweight reduction, the antiemetic effect, the reduction of ...
Battistina Asproni +3 more
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The Electrochemical Behavior of Al Alloys in NaCl Solution in the Presence of Pyrazole Derivative [PDF]
This paper studies the corrosion inhibition of Al-Mg alloy system in 0.5 mol/dm3 NaCl solution in the presence of pyrazole derivative using potentiodynamic polarization and linear polarization method.
Veselinka Grudic +4 more
doaj
On the Interactions of Fused Pyrazole Derivative with Selected Amino Acids: DFT Calculations
Due to the increasing prevalence of neoplasms, there is a permanent need for new selective cytostatic compounds. Anticancer drugs can act in different ways, affecting protein expression and synthesis, including disruption of signaling pathways within ...
Kornelia Czaja +7 more
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The reaction of prazolobenzothienopyrimidine-3-carbaldehyde 1 with thiocarbohydrazide afforded the Schiff’s base 3. The latter compound reacted with some electrophilic reagents to give 1,2,4-triazoles 4–6 and 1,2,4-triazines 7–9.
Kamelia El-mahdy +4 more
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SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL HETEROCYCLIC DERIVATIVES OF FLURBIPROFEN
The synthesis of some novel non- carboxylic heterocyclic derivatives of flurbiprofen such as pyrazole , pyrrole , oxadiazole, oxadiazines, and triazoles, is described. Structure of the new compounds was elucidated by spectroscopic data and microanalysis.
Mohamed El-Sadek +3 more
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(4Z)-4-[(2E)-1-Hydroxy-3-(4-methoxyphenyl)prop-2-enylidene]-3-methyl-1-phenyl-1H-pyrazol-5(4H)-one
The title compound, C20H18N2O4, is a chalcone derivative of pyrazole. The pyrazole ring is inclined at a dihedral angle of 19.29 (12)° to the methoxyphenyl ring mean plane, and by 1.19 (13)° to the phenyl ring.
Mukhtar-ul-Hassan +4 more
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Flavin Catalysts in Organic Synthesis
Flavins and their congeners are potent catalysts for organic synthesis inspired by enzymatic transformations. In addition to catalysis in the flavin ground state via covalent intermediates, the excited singlet and triplet states unlock applications including photooxidation, photoreduction, and energy transfer via sensitization.
Jan Freudenberg, Golo Storch
wiley +2 more sources
N‐Alkoxysulfurdiimide Reagents for the One‐Step Modular Synthesis of Primary Sulfonimidamides
N‐Alkoxysulfurdiimide reagents when combined with organometallic reagents lead directly to primary sulfonimidamide products. The reactions are broad in scope, encompassing aryl, heteroaryl, and alkyl carbon substituents. The reactivity of the N‐alkoxysulfurdiimide reagents can be correlated with the electron‐withdrawing ability of the N‐substituent ...
Suzanne E. Davison +6 more
wiley +2 more sources
A novel di-Mannich derivative of curcumin pyrazole, 2-[(2,6-dimethyl morpholin-4-yl)methyl]-4-[(E)-2-{3-[(E)-2-{3-[(2,6-dimethylmorpholin-4-yl)methyl]-4-hydroxy-5-methoxyphenyl}ethenyl]-1H-pyrazol-5-yl}ethenyl]-6-methoxyphenol (2), has been synthesized ...
Joko Untung +2 more
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