Results 21 to 30 of about 340,649 (242)

Inhibition of diacylglycerol–sensitive TRPC channels by synthetic and natural steroids [PDF]

, 2012
TRPC channels are a family of nonselective cation channels that regulate ion homeostasis and intracellular Ca2+ signaling in numerous cell types. Important physiological functions such as vasoregulation, neuronal growth, and pheromone recognition have ...
Kleemann, Heinz-Werner, Rütten, Hartmut, Hartmut Rütten (171202), Löhn Matthias, Thorsten Schmidt (5598), Thomas Licher (171199), Löhn, Matthias, Miehe Susanne, Dittrich Werner, Peter Crause, Carsten Strübing (171204), Schmidt, Thorsten, Miehe, Susanne, Susanne Miehe, Schmidt Thorsten, Carsten Strübing, Heinz-Werner Kleemann (171197), Peter Crause (171193), Dittrich, Werner, Licher, Thomas, Hartmut Rütten, Matthias Löhn, Strübing, Carsten, Rütten Hartmut, Matthias Löhn (171195), Strübing Carsten, Werner Dittrich, Licher Thomas, Thomas Licher, Heinz-Werner Kleemann, Werner Dittrich (171200), Kleemann Heinz-Werner, Crause, Peter, Susanne Miehe (171189), Crause Peter, Thorsten Schmidt   +35 more
core   +2 more sources

Image_2_PCW-1001, a Novel Pyrazole Derivative, Exerts Antitumor and Radio-Sensitizing Activities in Breast Cancer.tif

, 2022
As pyrazole and its derivatives have a wide range of biological activities, including anticancer activity, the design of novel pyrazole derivatives has emerged as an important research field.
Kwan-Young Jung (1621513), Jiyeon Ahn (624498), Ah-Young Kim (531209), Kyu Myung Lee (6185675), Sangwook Wu (8352264), Suk Joon Cho (12314645), Young-Ju Kwon (3445073), Jae-Sung Kim (605888), Navin Pandit (12314642), Jeong Su Oh (2802904), Minsung Kang (6458120)   +10 more
core   +1 more source

tert-Butyl 4-{[5-(4-chlorophenyl)-1-(4-fluorophenyl)-1H-pyrazol-3-yl]carbonyl}piperazine-1-carboxylate

Acta Crystallographica Section E, 2010
In the title pyrazole derivative, C25H26ClFN4O3, both benzene rings are twisted out of the plane through the pyrazole ring, with dihedral angles of 67.62 (10) and 27.63 (10)° for the fluoro- and chloro-substituted rings ...
Seik Weng Ng, S. Sarveswari, V. Vijayakumar, R. Venkat Ragavan, Edward R. T. Tiekink   +4 more
doaj   +1 more source

Tricyclic Pyrazole-Based Compounds as Useful Scaffolds for Cannabinoid CB₁/CB₂ Receptor Interaction

Molecules, 2021
Cannabinoids comprise different classes of compounds, which aroused interest in recent years because of their several pharmacological properties. Such properties include analgesic activity, bodyweight reduction, the antiemetic effect, the reduction of ...
Battistina Asproni, Gabriele Murineddu, Paola Corona, Gérard A. Pinna   +3 more
doaj   +1 more source

Table_1_PCW-1001, a Novel Pyrazole Derivative, Exerts Antitumor and Radio-Sensitizing Activities in Breast Cancer.docx

, 2022
As pyrazole and its derivatives have a wide range of biological activities, including anticancer activity, the design of novel pyrazole derivatives has emerged as an important research field.
Kwan-Young Jung (1621513), Jiyeon Ahn (624498), Ah-Young Kim (531209), Kyu Myung Lee (6185675), Sangwook Wu (8352264), Suk Joon Cho (12314645), Young-Ju Kwon (3445073), Jae-Sung Kim (605888), Navin Pandit (12314642), Jeong Su Oh (2802904), Minsung Kang (6458120)   +10 more
core   +1 more source

The Electrochemical Behavior of Al Alloys in NaCl Solution in the Presence of Pyrazole Derivative [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2019
This paper studies the corrosion inhibition of Al-Mg alloy system in 0.5 mol/dm3 NaCl solution in the presence of pyrazole derivative using potentiodynamic polarization and linear polarization method.
Veselinka Grudic, Ivana Boskovic, Dragan Radonjic, Zeljko Jacimovic, Bojana Knezevic   +4 more
doaj  

Labelling of a pyrazole derivative substance with I-131 and investigation of its radiopharmaceutical potantial [PDF]

, 2010
Tıpta, pirazol türevi bileşikler değişik amaçlar için kullanılmaktadır.4-benzoil-1-(4-karboksifenil)-5-fenil-1H-pirazol-3-karboksilik asit'in (pirazol türevi) 131I ile işaretlenerek radyofarmasötik potansiyelini incelemektir. İyodo pirazol türevi bileşik
Kurtdede, Esra
core   +1 more source

Synthesis, Characterization and ِAntimicrobial Activities of Some New Heterocyclic Schiff Bases Derived from Thiocarbohydrazide

Acta Chimica Slovenica, 2016
The reaction of prazolobenzothienopyrimidine-3-carbaldehyde 1 with thiocarbohydrazide afforded the Schiff’s base 3. The latter compound reacted with some electrophilic reagents to give 1,2,4-triazoles 4–6 and 1,2,4-triazines 7–9.
Kamelia El-mahdy, Azza El-Kazak, Mohamed Abdel-Megid, Magdy Seada, Osama Farouk   +4 more
doaj   +1 more source

Image_1_PCW-1001, a Novel Pyrazole Derivative, Exerts Antitumor and Radio-Sensitizing Activities in Breast Cancer.tif

, 2022
As pyrazole and its derivatives have a wide range of biological activities, including anticancer activity, the design of novel pyrazole derivatives has emerged as an important research field.
Kwan-Young Jung (1621513), Jiyeon Ahn (624498), Ah-Young Kim (531209), Kyu Myung Lee (6185675), Sangwook Wu (8352264), Suk Joon Cho (12314645), Young-Ju Kwon (3445073), Jae-Sung Kim (605888), Navin Pandit (12314642), Jeong Su Oh (2802904), Minsung Kang (6458120)   +10 more
core   +1 more source

SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL HETEROCYCLIC DERIVATIVES OF FLURBIPROFEN

Zagazig Journal of Pharmaceutical Sciences, 1998
The synthesis of some novel non- carboxylic heterocyclic derivatives of flurbiprofen such as pyrazole , pyrrole , oxadiazole, oxadiazines, and triazoles, is described. Structure of the new compounds was elucidated by spectroscopic data and microanalysis.
Mohamed El-Sadek , Lobna Abdel-Aziz , Mansour Abou-Kull , Kamel Metwally   +3 more
doaj   +1 more source