Results 41 to 50 of about 15,779 (274)

Recent advances in the synthesis and application of fluorescent α-amino acids [PDF]

, 2016
Fluorescence spectroscopy has become a powerful technique for probing a range of complex biological processes including enzyme mechanisms and protein-protein interactions. While the application of this technique uses a number of strategies, many of these
Harkiss, Alexander, Sutherland, Andrew
core   +1 more source

Synthesis and Chemical Characterisation of Some New Diheteroaryl Thienothiophene Derivatives

Molecules, 2011
Treatment of 1-(5-acetyl-3,4-dimethythieno[2,3-b]thiophene-2yl)ethanone (1) with dimethylformamide dimethyl acetal afforded enaminone derivative 2, which reacted with amino derivatives to give the corresponding bis-pyrimidine, bis-pyrazole, bis-triazolo ...
Abdullah S. Alamary, Abdullah Mohammad Al-Majid, Yahia Nasser Mabkhot   +2 more
doaj   +1 more source

Revisiting the structure and chemistry of 3(5)-Substituted Pyrazoles [PDF]

, 2019
Pyrazoles are known as versatile scaffolds in organic synthesis and medicinal chemistry, often used as starting materials for the preparation of more complex heterocyclic systems with relevance in the pharmaceutical field.
Alam, Alina Secrieru, Alkorta, Andes, Anwar, Behr, Brown, Castillo, Catalan, Chauhan, Clark, Elguero, Elnagdi, Favre, Fichez, Hall, Horta, Katritzky, Katritzky, Kost, Kumar, Larina, Maria Lurdes Santos Cristiano, Mert, Minkin, Minkin, Mohamed, Nagy, Nimbalkar, Paul Michael O’Neill, Schofield, Simons, Szajda, Taylor, Zerbi   +34 more
core   +2 more sources

The investigation of the reactions of some pyrazole-3-carboxylic acids with various diamines and diols

Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2012
In this study, some new derivatives were synthesized of 4-benzoyl-1-(3-nitrophenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid (1) and 4-(ethoxycarbonyl)-1-(3-nitrophenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid (2) that they were pyrazole carboxylic acid ...
Rahmi Kasımoğulları, Makbule Maden, Samet Mert   +2 more
doaj   +1 more source

3,5-Dimethyl-1-(4-nitrophenyl)-1H-pyrazole

Acta Crystallographica Section E, 2012
In the title pyrazole derivative, C11H11N3O2, the benzene ring is twisted [dihedral angle = 31.38 (12)°] with respect to the pyrazole ring (r.m.s. deviation = 0.009 Å).
Edward R. T. Tiekink, Solange M. S. V. Wardell, James L. Wardell   +2 more
doaj   +1 more source

One‐Dimensional Materials Supported in Two‐Dimensional Van der Waals Metal–Organic Frameworks with Optical Anisotropy Switching via Twist‐Engineering

Advanced Materials, EarlyView.
We introduce a molecular strategy to assemble one‐dimensional (1D) materials into two‐dimensional (2D) van der Waals metal–organic frameworks (MOFs). Crystals of [FeX(pzX)(bpy)] (X = Cl, F) form anisotropic 2D layers that can be mechanically exfoliated into thin sheets.
Eleni C. Mazarakioti, Carla Boix‐Constant, Iván Gómez‐Muñoz, Diego López‐Alcalá, Sergio Revuelta, Marco Ballabio, Vasileios Balos, José J. Baldoví, Enrique Cánovas, Josep Canet‐Ferrer, Guillermo Mínguez Espallargas, Samuel Mañas‐Valero, Eugenio Coronado   +12 more
wiley   +1 more source

Efficient Regioselective Iodination of Pyrazole Derivatives Mediated by Cadmium(II) Acetate

ChemistryOpen
The present study focuses on the iodination of pyrazoles mediated by cadmium (II) acetate. The objects of research were compounds with pyrazole rings substituted by N‐propargyl, C, N‐alkyl groups.
Dr. Nina G. Hobosyan, Dr. Kristine V. Balyan, Lusine A. Movsisyan, Dr. Varduhi S. Hovsepyan, Armen G. Ayvazyan, Dr. Henrik A. Panosyan, Prof. Dr. Hovhannes S. Attaryan, Dr. Hmayak B. Sargsyan, Haykanush R. Pogosyan   +8 more
doaj   +1 more source

Characterization of Stable Pyrazole Derivatives of Curcumin with Improved Cytotoxicity on Osteosarcoma Cell Lines

Life, 2023
Curcumin (CUR) is a natural molecule that is unstable due to the presence of a bis-ketone. To obtain more stable derivatives in biological fluids, the bis-ketone was replaced with pyrazole or O-substituted oximes.
Giordana Feriotto, Riccardo Rondanin, Paolo Marchetti, Federico Tagliati, Simone Beninati, Claudio Tabolacci, Elisa Grusi, Serena Aguzzi, Carlo Mischiati   +8 more
doaj   +1 more source

Seven coordinate molybdenum and tungsten complexes containing Tpm and Tpm derivatives and the impact of ligand substitution on NMR chemical shifts [PDF]

, 2019
A series of known and new seven coordinate molybdenum and tungsten complexes of tris(pyrazolyl)methane (Tpm) and substituted Tpm, [TpmM(CO)3X]+, have been synthesized. Depending on the identity of X, (bromo, iodo, hydrido) and the substitution of the Tpm
Seager, Cole
core   +1 more source

Inhibition of dengue virus replication by novel inhibitors of RNA-dependent RNA polymerase and protease activities [PDF]

, 2017
Dengue virus (DENV) is the leading mosquito-transmitted viral infection in the world. With more than 390 million new infections annually, and up to 1 million clinical cases with severe disease manifestations, there continues to be a need to develop new ...
Coluccia, A., Famiglini, V., Hiscott, J., La Regina, G., Lee, J. C., Masci, D., Pelliccia, S., Silvestri, R., Tseng, C. K., Wub, Y. H.   +9 more
core   +1 more source