Results 171 to 180 of about 27,892 (233)

Syntheses of [1]Benzopyrano[4,3-c]pyrazoles and -[3,4-d]isoxazoles [PDF]

open access: bronze, 1981
Tomio Shimizu   +4 more
openalex   +1 more source

Peptide Backbone Editing via Post-Translational O to C Acyl Shift. [PDF]

open access: yesJ Am Chem Soc
Schissel CK   +6 more
europepmc   +1 more source

Fundamental Aspects of SPPS and Green Chemical Peptide Synthesis

open access: yesJournal of Peptide Science, Volume 31, Issue 5, May 2025.
Proposed green chemical synthesis scheme for efficient preparation of a (hypothetical) 20 residue peptide. Aqueous SPPS employing N‐carboxyanhydrides (NCAs) minimal side chain protection, sample displacement mode HPLC purification and convergent condensation of unprotected peptide segments by native chemical ligation in aqueous solution.
Stephen B. H. Kent
wiley   +1 more source

A Versatile Carbonylative Approach to Ureas and Carbamates through Light Activated Nickel Catalyzed Formation of Aliphatic Isocyanates

open access: yesAngewandte Chemie, Volume 137, Issue 17, April 17, 2025.
A versatile carbonylative approach to prepare aliphatic ureas and carbamates has been developed. The reaction functions with an earth abundant nickel catalyst to generate electrophilic isocyanates from C(sp3) halides, azide and carbon monoxide.
Cuihan Zhou   +2 more
wiley   +2 more sources

Validation of ion mobility spectrometry ‐ mass spectrometry as a screening tool to identify type II kinase inhibitors of FGFR1 kinase

open access: yesRapid Communications in Mass Spectrometry, Volume 39, Issue S1, May 2025.
Rationale The protein kinase FGFR1 regulates cellular processes in human development. As over‐activity of FGFR1 is implicated with cancer, effective inhibitors are in demand. Type I inhibitors, which bind to the active form of FGFR1, are less effective than type II inhibitors, which bind to the inactive form. Screening to distinguish between type I and
Helen S. Beeston   +6 more
wiley   +1 more source

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