Results 61 to 70 of about 40,394 (295)

An Example of Polynomial Expansion: The Reaction of 3(5)-Methyl-1H-Pyrazole with Chloroform and Characterization of the Four Isomers

Molecules, 2019
The reaction in phase-transfer catalyzed conditions of 3(5)-methyl-1H-pyrazole with chloroform affords four isomers 333, 335, 355 and 555 in proportions corresponding to the polynomial expansion (a + b)3, with a = 0.6 and b = 0.4, a and b being 3-methyl ...
Vera L. M. Silva, Artur M. S. Silva, Rosa M. Claramunt, Dionisia Sanz, Lourdes Infantes, Ángela Martínez-López, Felipe Reviriego, Ibon Alkorta, José Elguero   +8 more
doaj   +1 more source

Metal Acetylides in Cycloaddition Reactions [PDF]

, 2017
This review highlights recent advances in the synthesis of (hetero)aromatic systems via cycloaddition reactions of alkynylmetals with dienes and dipoles.
Comas-Barceló, J., Harrity, J.P.A.
core   +1 more source

The Relationship Between Aldose Reductase and Isoxazole Derivatives: An In Vitro and In Silico Approach to Its Correlation With Diabetic Conditions

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Diabetes mellitus (DM), which can result in a number of problems such as cataracts, neuropathy, retinopathy, nephropathy, and several cardiovascular illnesses, continues to be a growing issue despite major advancements in treatment approaches.
Ahmet Esat Göner, Hatice Esra Duran
wiley   +1 more source

(E)-5-(4-Methoxyphenyl)-N′-(2-oxoindolin-3-ylidene)-1-phenyl-1H-pyrazole-3-carbohydrazide

IUCrData, 2023
The asymmetric unit of the title compound, C25H19N5O3, is composed of two independent molecules with slightly different conformations. The extended structure features N—H...O hydrogen bonds as well as π–π interactions.
Bakr F. Abdel-Wahab, Abdelbasset A. Farahat, Mohamed S. Bekheit, Emad Yousif, Benson M. Kariuki, Gamal A. El-Hiti   +5 more
doaj   +1 more source

Hydrazones as Singular Reagents in Asymmetric Organocatalysis [PDF]

, 2016
This Minireview summarizes strategies and developments regarding the use of hydrazones as reagents in asymmetric organocatalysis, their distinct roles in nucleophile–electrophile, cycloaddition, and cyclization reactions.
Fernández Fernández, Rosario Fátima, Lassaletta, José M., Matador Martínez, Esteban, Monge Fernández, David, Retamosa Hernández, María Gracia   +4 more
core   +1 more source

Engineering of 2‐ketoacid Decarboxylases for Production of Isobutanol and Other Fusel Alcohols in Saccharomyces cerevisiae

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Isobutanol is a fusel alcohol that can be produced microbially for use as a biofuel or upgraded into sustainable aviation fuel (SAF). A key enzyme in the isobutanol biosynthetic pathway is 2‐ketoacid decarboxylase (KDC), which irreversibly decarboxylates 2‐ketoisovalerate (KIV) to yield isobutyraldehyde.
Joshua J. Dietrich, Maelia Dziedzic, Jia Sun, Sri Harsha Adusumilli, Carla Gonçalves, Chris Todd Hittinger, Brian F. Pfleger   +6 more
wiley   +1 more source

Introducing the Cis‐2,3‐Bis(trifluoromethyl)cyclopropyl Chemotype: Late‐Stage Installation and Stereoelectronic Properties

ChemistryEurope, EarlyView.
The cis‐2,3‐bis(trifluoromethyl)cyclopropyl chemotype is introduced. The steric demand of this motif is intermediate between that of the heptafluoroisopropyl and prefluorotertbutyl groups; yet, it induces significantly less lipophilicity than these due to its facial polarity.
Daniel Gaviña, Zeyu Feng, David Herrero, Martin Simon, Christopher Golz, Manuel Alcarazo   +5 more
wiley   +1 more source

Synthesis of 4-functionalized pyrazoles via oxidative thio- or selenocyanation mediated by PhICl2 and NH4SCN/KSeCN

Beilstein Journal of Organic Chemistry
A series of 4-thio/seleno-cyanated pyrazoles was conveniently synthesized from 4-unsubstituted pyrazoles using NH4SCN/KSeCN as thio/selenocyanogen sources and PhICl2 as the hypervalent iodine oxidant.
Jialiang Wu, Haofeng Shi, Xuemin Li, Jiaxin He, Chen Zhang, Fengxia Sun, Yunfei Du   +6 more
doaj   +1 more source

N\u3csup\u3e1\u3c/sup\u3e-Acetyl-3\u27-methylandrosta-4,16-dieno[16,17-\u3cem\u3ed\u3c/em\u3e]pyrazole-3-one [PDF]

, 1994
In an attempt to find the structural features promoting the thermal isomerization of the N-acylated steroid [16,17-d]pyrazoles into [17,16-c]pyrazole derivatives,the X-ray structure analysis of the title compound, C23H30N2O3, (1), has been carried out ...
Kamernitzky, Alexey V., Lindeman, Sergey V., Nava, Ezequiel Huipe, Skorova, Alina V., Vesela, Irina V., Yanovsky, Alexandr I.   +5 more
core   +1 more source

Cu-catalysed pyrazole synthesis in continuous flow [PDF]

, 2016
The synthesis of 1,4-disubstituted pyrazoles via the cycloaddition reaction of sydnones and terminal alkynes has been achieved employing silica-supported copper catalysts. Furthermore, this methodology has been successfully implemented in continuous flow
Arbaciauskiené, Bao, Baxendale, Bogdan, Browne, Browne, Browne, Comas-Barceló, Decuypere, Foster, Foster, Fuchs, Fustero, Girard, Ishibuchi, King, King, Kolodych, Lamberth, Mao, Miao, Miao, Normant, Opalka, Specklin, Theunissen, Wu   +26 more
core   +3 more sources